Fully synthetic human combinatorial antibody libraries (HuCAL) based on modular consensus frameworks and CDRs randomized with trinucleotides.
Achim Knappik;Liming Ge;Annemarie Honegger;Peter Pack.
Journal of Molecular Biology (2000)
Reliable cloning of functional antibody variable domains from hybridomas and spleen cell repertoires employing a reengineered phage display system
Anke Krebber;Susanne Bornhauser;Jörg Burmester;Annemarie Honegger.
Journal of Immunological Methods (1997)
Point mutation at the ATP binding site of EGF receptor abolishes protein-tyrosine kinase activity and alters cellular routing.
A.M. Honegger;T.J. Dull;S. Felder;E. Van Obberghen.
Point mutation in FGF receptor eliminates phosphatidylinositol hydrolysis without affecting mitogenesis
M. Mohammadi;C. A. Dionne;W. Li;N. Li.
Yet Another Numbering Scheme for Immunoglobulin Variable Domains: An Automatic Modeling and Analysis Tool
Annemarie Honegger;Andreas Plückthun.
Journal of Molecular Biology (2001)
A tyrosine-phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (Flg) is a binding site for the SH2 domain of phospholipase C-gamma 1.
M Mohammadi;A M Honegger;D Rotin;R Fischer.
Molecular and Cellular Biology (1991)
Stability improvement of antibodies for extracellular and intracellular applications: CDR grafting to stable frameworks and structure-based framework engineering.
Stefan Ewert;Annemarie Honegger;Andreas Plückthun.
Disrupting the hydrophobic patches at the antibody variable/constant domain interface: improved in vivo folding and physical characterization of an engineered scFv fragment.
L Nieba;A Honegger;C Krebber;A Plückthun.
Protein Engineering (1997)
Biophysical properties of human antibody variable domains
Stefan Ewert;Thomas Huber;Annemarie Honegger;Andreas Plückthun.
Journal of Molecular Biology (2003)
Domain interactions in the Fab fragment: a comparative evaluation of the single-chain Fv and Fab format engineered with variable domains of different stability
Daniela Röthlisberger;Annemarie Honegger;Andreas Plückthun.
Journal of Molecular Biology (2005)
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