World's Best Scientists 2026 revealed!
Uwe Zangemeister-Wittke

Uwe Zangemeister-Wittke

D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
9378
World Ranking
14613
National Ranking
268

Uwe Zangemeister-Wittke publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Uwe Zangemeister-Wittke sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 131 publications — 17th percentile

17% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Uwe Zangemeister-Wittke D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Uwe Zangemeister-Wittke sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 56 D-Index — 28th percentile

28% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Uwe Zangemeister-Wittke is affiliated with the University of Bern in Switzerland. Their research spans the fields of biochemistry, genetics, and molecular biology, with a particular focus also on medicine. Within these fields, their work covers several subfields including molecular biology, radiology, nuclear medicine and imaging, and oncology.

The scientist's main research topics include:

  • Monoclonal and Polyclonal Antibodies Research
  • PI3K/AKT/mTOR signaling in cancer
  • HER2/EGFR in Cancer Research
  • Radiopharmaceutical Chemistry and Applications
  • Sphingolipid Metabolism and Signaling
  • Protein Kinase Regulation and GTPase Signaling
  • Protein purification and stability

Zangemeister-Wittke has published papers in several scientific journals, including:

  • Journal of Controlled Release
  • International Journal of Molecular Sciences
  • European Journal of Pharmaceutics and Biopharmaceutics
  • Clinical Cancer Research

Notable recent publications include:

  • Optimizing the anti-tumor efficacy of protein-drug conjugates by engineering the molecular size and half-life (2020), Journal of Controlled Release
  • Ceramide Kinase Is Upregulated in Metastatic Breast Cancer Cells and Contributes to Migration and Invasion by Activation of PI 3-Kinase and Akt (2020), International Journal of Molecular Sciences
  • Half-life extension of efficiently produced DARPin serum albumin fusions as a function of FcRn affinity and recycling (2021), European Journal of Pharmaceutics and Biopharmaceutics
  • Correction: Targeting the Phosphoinositide 3-Kinase p110-α Isoform Impairs Cell Proliferation, Survival, and Tumor Growth in Small Cell Lung Cancer (2025), Clinical Cancer Research

Frequent co-authors collaborating with Zangemeister-Wittke include:

  • Fabian Brandl
  • Andreas Plückthun
  • Sarah D. Busslinger
  • Stephanie Schwalm
  • Martin Erhardt

Best Publications

  • A Novel Antisense Oligonucleotide Targeting Survivin Expression Induces Apoptosis and Sensitizes Lung Cancer Cells to Chemotherapy

    R A Olie;A P Simões-Wüst;B Baumann;S H Leech

  • Silencing of death receptor and caspase-8 expression in small cell lung carcinoma cell lines and tumors by DNA methylation

    Sally Hopkins-Donaldson;Annmarie Ziegler;S. Kurtz;C. Bigosch

  • Induction of Apoptosis in Small-Cell Lung Cancer Cells by an Antisense Oligodeoxynucleotide Targeting the Bcl-2 Coding Sequence

    Annemarie Ziegler;Gerd H. Luedke;Doriano Fabbro;Karl Heinz Altmann

  • High thermal stability is essential for tumor targeting of antibody fragments: engineering of a humanized anti-epithelial glycoprotein-2 (epithelial cell adhesion molecule) single-chain Fv fragment.

    J Willuda;A Honegger;R Waibel;P A Schubiger

  • Circulating DNA: a new diagnostic gold mine?

    Annemarie Ziegler;Uwe Zangemeister-Wittke;Rolf A Stahel

  • Antisense therapy for cancer—the time of truth

    Burkhard Jansen;Uwe Zangemeister-Wittke

  • Inflammation-associated Cell Cycle–independent Block of Apoptosis by Survivin in Terminally Differentiated Neutrophils

    Frank Altznauer;Sibylla Martinelli;Shida Yousefi;Christine Thürig

  • Activity of a Novel bcl-2/bcl-xL-Bispecific Antisense Oligonucleotide Against Tumors of Diverse Histologic Origins

    Oliver Gautschi;Stefan Tschopp;Robert A. Olie;Siân H. Leech

  • The sphingosine 1-phosphate receptor modulator fingolimod as a therapeutic agent: Recent findings and new perspectives.

    Andrea Huwiler;Uwe Zangemeister-Wittke

  • A Novel Bispecific Antisense Oligonucleotide Inhibiting Both bcl-2 and bcl-xL Expression Efficiently Induces Apoptosis in Tumor Cells

    U Zangemeister-Wittke;S H Leech;R A Olie;A P Simões-Wüst

  • Synergistic cytotoxicity of bcl-2 antisense oligodeoxynucleotides and etoposide, doxorubicin and cisplatin on small-cell lung cancer cell lines.

    U Zangemeister-Wittke;T Schenker;GH Luedke;RA Stahel

  • Role for Bcl-xL in Delayed Eosinophil Apoptosis Mediated by Granulocyte-Macrophage Colony-Stimulating Factor and Interleukin-5

    Birgit Dibbert;Isabelle Daigle;Doris Braun;Corinna Schranz

  • A recombinant immunotoxin derived from a humanized epithelial cell adhesion molecule-specific single-chain antibody fragment has potent and selective antitumor activity.

    Claudio Di Paolo;Jörg Willuda;Susanne Kubetzko;Ikar Lauffer

  • PEGylation and multimerization of the anti-p185HER-2 single chain Fv fragment 4D5: effects on tumor targeting.

    Susanne Kubetzko;Ela Balic;Robert Waibel;Uwe Zangemeister-Wittke

  • Involvement of hTERT in apoptosis induced by interference with Bcl-2 expression and function.

    D Del Bufalo;A Rizzo;D Trisciuoglio;G Cardinali

  • DARPins recognizing the tumor-associated antigen EpCAM selected by phage and ribosome display and engineered for multivalency.

    Nikolas Stefan;Patricia Martin-Killias;Sascha Wyss-Stoeckle;Annemarie Honegger

  • Induction of apoptosis in lung-cancer cells following bcl-xL anti-sense treatment.

    Siân H. Leech;Robert A. Olie;Oliver Gautschi;A. Paula Simões‐Wüst

  • Tumor Targeting of Mono-, Di-, and Tetravalent Anti-p185HER-2 Miniantibodies Multimerized by Self-associating Peptides

    Jörg Willuda;Susanne Kubetzko;Robert Waibel;P. August Schubiger

  • Cisplatin activates Akt in small cell lung cancer cells and attenuates apoptosis by survivin upregulation

    Larisa L. Belyanskaya;Sally Hopkins-Donaldson;Stefanie Kurtz;Ana Paula Simões-Wüst

  • Antitumor activity of an epithelial cell adhesion molecule targeted nanovesicular drug delivery system.

    Sajid Hussain;Andreas Plückthun;Theresa M. Allen;Uwe Zangemeister-Wittke

Frequent Co-Authors

Rolf A. Stahel
Rolf A. Stahel University of Zurich
Andreas Plückthun
Andreas Plückthun University of Zurich
Andrea Huwiler
Andrea Huwiler University of Bern
Hans-Uwe Simon
Hans-Uwe Simon University of Bern
Doriano Fabbro
Doriano Fabbro Novartis (Switzerland)
Gabriella Zupi
Gabriella Zupi École Normale Supérieure de Lyon
Martin E. Gleave
Martin E. Gleave University of British Columbia
Josef Pfeilschifter
Josef Pfeilschifter Goethe University Frankfurt
Robert Häner
Robert Häner University of Bern
Burkhard Jansen
Burkhard Jansen University of British Columbia

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