World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
52
Citations
8797
World Ranking
16781
National Ranking
592

Overview

Burkhard Jansen is affiliated with the University of British Columbia in Canada. Their research primarily focuses on medical and biochemistry fields, with particular emphasis on oncology, molecular biology, epidemiology, and dermatology. The scientist's work spans across multiple disciplines such as molecular biology techniques, skin cancer studies, and infectious diseases.

Jansen has contributed to the study and management of cutaneous melanoma detection and associated topics, with a significant number of publications addressing this area. Their research topics include:

  • Cutaneous Melanoma Detection and Management
  • Nonmelanoma Skin Cancer Studies
  • Molecular Biology Techniques and Applications
  • Infectious Diseases and Mycology
  • Cell Image Analysis Techniques
  • Skin Protection and Aging
  • Melanin and Skin Pigmentation

The scientist has published numerous papers in notable venues, including:

  • SKIN The Journal of Cutaneous Medicine
  • Journal of Investigative Dermatology
  • Journal of the American Academy of Dermatology
  • Journal of Drugs in Dermatology
  • Breast Cancer Research and Treatment

Among the recent papers authored or coauthored by Jansen are:

  • "Real-World Utility of a Non-Invasive Gene Expression Test to Rule Out Primary Cutaneous Melanoma: A Large US Registry Study" (2020), Journal of Drugs in Dermatology
  • "Non-Invasive Detection of Genomic Atypia Increases Real-World NPV and PPV of the Melanoma Diagnostic Pathway and Reduces Biopsy Burden" (2021), SKIN The Journal of Cutaneous Medicine
  • "Risk Stratification of Severely Dysplastic Nevi by Non-Invasively Obtained Gene Expression and Mutation Analyses" (2020), SKIN The Journal of Cutaneous Medicine
  • "Genomic Atypia to Enrich Melanoma Positivity in Biopsied Lesions: Gene Expression and Pathology Findings From a Large U.S. Registry Study" (2021), SKIN The Journal of Cutaneous Medicine
  • "Non-invasive Gene Expression Analysis Rules Out Melanoma with High Negative Predictive Value Regardless of Skin Phototype" (2024), SKIN The Journal of Cutaneous Medicine

Jansen frequently collaborates with several researchers in the field, including:

  • Maral Skelsey
  • Michael Howell
  • Zuxu Yao
  • Gary L. Peck
  • Loren E. Clarke

Best Publications

  • Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c

    Thierry Rossé;Reynald Olivier;Laurent Monney;Monika Rager

  • Chemosensitisation of malignant melanoma by BCL2 antisense therapy

    B Jansen;V Wacheck;E Heere-Ress;H Schlagbauer-Wadl

  • bcl-2 antisense therapy chemosensitizes human melanoma in SCID mice.

    Burkhard Jansen;Hermine Schlagbauer-Wadl;Bob D. Brown;Robert N. Bryan

  • Silencing expression of the clusterin/apolipoprotein j gene in human cancer cells using small interfering RNA induces spontaneous apoptosis, reduced growth ability, and cell sensitization to genotoxic and oxidative stress.

    Ioannis P. Trougakos;Alan So;Burkhard Jansen;Martin E. Gleave

  • Hepatocytes convert to a fibroblastoid phenotype through the cooperation of TGF-β1 and Ha-Ras: steps towards invasiveness

    Josef Gotzmann;Heidemarie Huber;Christiane Thallinger;Markus Wolschek

  • Antisense therapy for cancer—the time of truth

    Burkhard Jansen;Uwe Zangemeister-Wittke

  • Effects of Betulinic Acid Alone and in Combination with Irradiation in Human Melanoma Cells

    Edgar Selzer;Emilio Pimentel;Volker Wacheck;Werner Schlegel

  • An Endogenous Retrovirus Derived from Human Melanoma Cells

    Thomas Muster;Andrea Waltenberger;Andreas Grassauer;Sonja Hirschl

  • Expression of Bcl-2 family members in human melanocytes, in melanoma metastases and in melanoma cell lines.

    E Selzer;H Schlagbauer-Wadl;I Okamoto;H Pehamberger

  • The ETV6-NTRK3 gene fusion encodes a chimeric protein tyrosine kinase that transforms NIH3T3 cells.

    Daniel H. Wai;Stevan R. Knezevich;Trevor Lucas;Burkhard Jansen

  • Role of an acidic compartment in tumor-necrosis-factor-alpha-induced production of ceramide, activation of caspase-3 and apoptosis.

    Laurent Monney;Reynald Olivier;Isabelle Otter;Burkhard Jansen

  • Development and validation of a noninvasive 2-gene molecular assay for cutaneous melanoma

    Pedram Gerami;Zuxu Yao;David Polsky;Burkhard Jansen

  • Mcl-1 Antisense Therapy Chemosensitizes Human Melanoma in a SCID Mouse Xenotransplantation Model

    Christiane Thallinger;Markus F. Wolschek;Volker Wacheck;Helmut Maierhofer

  • Specific systemic nonviral gene delivery to human hepatocellular carcinoma xenografts in SCID mice

    Markus F. Wolschek;Christiane Thallinger;Malgorzata Kursa;Vanessa Rössler

  • Novel Ras antagonist blocks human melanoma growth

    B. Jansen;H. Schlagbauer-Wadl;H. Kahr;E. Heere-Ress

  • Characterization of peripheral-compartment kinetics of antibiotics by in vivo microdialysis in humans.

    M Müller;O Haag;T Burgdorff;A Georgopoulos

  • Melanoma progression–associated glycoprotein MUC18/MCAM mediates homotypic cell adhesion through interaction with a heterophilic ligand

    Judith P. Johnson;Menashe Bar-Eli;Burkhard Jansen;Edith Markhof

  • 5-Fluorouracil Kinetics in the Interstitial Tumor Space: Clinical Response in Breast Cancer Patients

    Markus Müller;Robert M. Mader;Birgit Steiner;Günther G. Steger

  • Bcl-2 antisense oligonucleotides (G3139) inhibit Merkel cell carcinoma growth in SCID mice.

    Hermine Schlagbauer-Wadl;Gabriele Klosner;Elisabeth Heere-Ress;Stefan Waltering

  • Adrenoceptor Hyporeactivity Is Responsible for Escherichia coli Endotoxin–Induced Acute Vascular Dysfunction in Humans

    Johannes Pleiner;Elisabeth Heere-Ress;Herbert Langenberger;Anna E. Sieder

Frequent Co-Authors

Klaus Wolff
Klaus Wolff Medical University of Vienna
Martin E. Gleave
Martin E. Gleave University of British Columbia
Hans-Georg Eichler
Hans-Georg Eichler European Medicines Agency
Markus Müller
Markus Müller Medical University of Vienna
Yoel Kloog
Yoel Kloog Tel Aviv University
Brett P. Monia
Brett P. Monia Ionis Pharmaceuticals (United States)
John H. Kersey
John H. Kersey University of Minnesota
Christoph Borner
Christoph Borner University of Freiburg
Uwe Zangemeister-Wittke
Uwe Zangemeister-Wittke University of Bern
Poul H. Sorensen
Poul H. Sorensen University of British Columbia

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