2017 - Member of the European Academy of Sciences
His primary areas of investigation include Transfection, Gene delivery, Molecular biology, DNA and Biochemistry. His Transfection research is multidisciplinary, incorporating elements of Endocytosis, Reporter gene and Genetic transfer. His work carried out in the field of Gene delivery brings together such families of science as Lipid bilayer fusion, Gene expression and Endosome.
His Molecular biology research is multidisciplinary, incorporating perspectives in Transcription factor, HeLa, Adenoviridae, Genetic enhancement and Cell biology. His research integrates issues of Polylysine and Recombinant DNA in his study of DNA. Ernst Wagner has researched Biochemistry in several fields, including Biophysics and In vivo.
Ernst Wagner spends much of his time researching Transfection, Biochemistry, Gene delivery, Molecular biology and Nucleic acid. His Transfection research focuses on subjects like DNA, which are linked to Polylysine. The Biochemistry study combines topics in areas such as Biophysics and In vivo.
His research in Gene delivery tackles topics such as Nanotechnology which are related to areas like Polymer. His Molecular biology research is multidisciplinary, relying on both Transferrin, Gene expression, Gene, Endocytosis and Cell biology. The concepts of his Nucleic acid study are interwoven with issues in RNA, Cell, Cationic polymerization and Combinatorial chemistry.
Ernst Wagner focuses on Biochemistry, Nucleic acid, Biophysics, Gene delivery and Cell biology. His studies examine the connections between Biochemistry and genetics, as well as such issues in Oligomer, with regards to Ligand. His Nucleic acid study combines topics in areas such as Nanotechnology, DNA, Intracellular, Cationic polymerization and Computational biology.
Endocytosis is closely connected to Endosome in his research, which is encompassed under the umbrella topic of Biophysics. Ernst Wagner usually deals with Gene delivery and limits it to topics linked to Molecular biology and Luciferase. His Transfection research is mostly focused on the topic Polyethylenimine.
The scientist’s investigation covers issues in Gene silencing, Biochemistry, Nucleic acid, Gene delivery and Cell biology. His works in Transfection and Cytotoxicity are all subjects of inquiry into Biochemistry. In his research, Ernst Wagner undertakes multidisciplinary study on Transfection and Redox homeostasis.
His Nucleic acid study combines topics from a wide range of disciplines, such as Cationic polymerization, Tyrosine, Nanotechnology and DNA. His Gene delivery study contributes to a more complete understanding of Genetic enhancement. Ernst Wagner interconnects Molecular biology and Cancer chemotherapy in the investigation of issues within Genetic enhancement.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Transferrin-polycation conjugates as carriers for DNA uptake into cells
Ernst Wagner;Martin Zenke;Matt Cotten;Hartmut Beug.
Proceedings of the National Academy of Sciences of the United States of America (1990)
The influence of endosome-disruptive peptides on gene transfer using synthetic virus-like gene transfer systems.
Christian Plank;Berndt Oberhauser;Karl Mechtler;Christian Koch.
Journal of Biological Chemistry (1994)
Influenza virus hemagglutinin HA-2 N-terminal fusogenic peptides augment gene transfer by transferrin-polylysine-DNA complexes: toward a synthetic virus-like gene-transfer vehicle.
Ernst Wagner;Christian Plank;Kurt Zatloukal;Matt Cotten.
Proceedings of the National Academy of Sciences of the United States of America (1992)
Adenovirus enhancement of transferrin-polylysine-mediated gene delivery.
David T. Curiel;Santosh Agarwal;Ernst Wagner;Matt Cotten.
Proceedings of the National Academy of Sciences of the United States of America (1991)
Different behavior of branched and linear polyethylenimine for gene delivery in vitro and in vivo.
Lionel Wightman;Ralf Kircheis;Vanessa Rössler;Sebastian Carotta.
Journal of Gene Medicine (2001)
Design and gene delivery activity of modified polyethylenimines
Ralf Kircheis;Lionel Wightman;Ernst Wagner.
Advanced Drug Delivery Reviews (2001)
Activation of the Complement System by Synthetic DNA Complexes: A Potential Barrier for Intravenous Gene Delivery
Christian Plank;Karl Mechtler;Francis C. Szoka;Ernst Wagner.
Human Gene Therapy (1996)
Transferrin-polycation-DNA complexes: the effect of polycations on the structure of the complex and DNA delivery to cells.
Ernst Wagner;Matt Cotten;Roland Foisner;Max L. Birnstiel.
Proceedings of the National Academy of Sciences of the United States of America (1991)
Coupling of adenovirus to transferrin-polylysine/DNA complexes greatly enhances receptor-mediated gene delivery and expression of transfected genes.
Ernst Wagner;Kurt Zatloukal;Matt Cotten;Helen Kirlappos.
Proceedings of the National Academy of Sciences of the United States of America (1992)
Polylysine-based transfection systems utilizing receptor-mediated delivery.
Wolfgang Zauner;Manfred Ogris;Ernst Wagner.
Advanced Drug Delivery Reviews (1998)
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