What is he best known for?
The fields of study he is best known for:
Karl Mechtler mostly deals with Cell biology, Genetics, Biochemistry, Cohesin and Molecular biology.
His Mitosis study in the realm of Cell biology connects with subjects such as Neuroblast.
His work on Biochemistry deals in particular with Histone code, Histone methyltransferase, Histone lysine methylation, Peptide and Peptide sequence.
Karl Mechtler interconnects EZH2 and Histone H1 in the investigation of issues within Histone code.
His work deals with themes such as Histone H2A, Chromatin remodeling and Histone H3, which intersect with Histone H1.
His studies in Molecular biology integrate themes in fields like DNA and Cell culture, Transfection.
His most cited work include:
- Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins. (2353 citations)
- Regulation of chromatin structure by site-specific histone H3 methyltransferases (2262 citations)
- Loss of the Suv39h Histone Methyltransferases Impairs Mammalian Heterochromatin and Genome Stability (1393 citations)
What are the main themes of his work throughout his whole career to date?
Karl Mechtler mainly focuses on Cell biology, Mass spectrometry, Biochemistry, Proteomics and Chromatography.
Karl Mechtler has researched Cell biology in several fields, including Chromatin, Cohesin and Chromosome segregation.
His Mass spectrometry research is multidisciplinary, incorporating perspectives in Combinatorial chemistry and Search engine.
His study in Biochemistry focuses on Histone methyltransferase and Histone code.
His research integrates issues of Proteome and Computational biology in his study of Proteomics.
His work investigates the relationship between Chromatography and topics such as Peptide that intersect with problems in Peptide sequence.
He most often published in these fields:
- Cell biology (47.44%)
- Mass spectrometry (22.44%)
- Biochemistry (20.83%)
What were the highlights of his more recent work (between 2018-2021)?
- Cell biology (47.44%)
- Mass spectrometry (22.44%)
- Proteomics (19.55%)
In recent papers he was focusing on the following fields of study:
Karl Mechtler focuses on Cell biology, Mass spectrometry, Proteomics, Chromatin and CTCF.
His Cell biology research is multidisciplinary, incorporating elements of Gene expression, Transcription factor, Mutant, Gene and Regulation of gene expression.
The study incorporates disciplines such as False discovery rate, Search engine and Identification in addition to Mass spectrometry.
His Proteomics research is within the category of Biochemistry.
In his research, Karl Mechtler performs multidisciplinary study on Biochemistry and Exonuclease.
His work in Chromatin addresses issues such as Histone, which are connected to fields such as Centromere, NASP and Chaperone.
Between 2018 and 2021, his most popular works were:
- Absolute quantification of cohesin, CTCF and their regulators in human cells. (40 citations)
- Absolute quantification of cohesin, CTCF and their regulators in human cells. (40 citations)
- First Community-Wide, Comparative Cross-Linking Mass Spectrometry Study. (38 citations)
In his most recent research, the most cited papers focused on:
Cell biology, Mass spectrometry, Chromatin, Transcription factor and Computational biology are his primary areas of study.
The concepts of his Cell biology study are interwoven with issues in Autophagy, ATG8, Quantitative proteomics, Ribosome and Kinetochore.
His work in the fields of Mass spectrometry, such as Fragmentation, intersects with other areas such as Reagent, White paper and Reliability.
In general Chromatin study, his work on Cohesin often relates to the realm of CTCF, thereby connecting several areas of interest.
His Transcription factor study integrates concerns from other disciplines, such as Kinase, Protein kinase A, Phosphorylation, Immune system and Induced pluripotent stem cell.
His study with Phosphatase involves better knowledge in Biochemistry.
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