2023 - Research.com Genetics in Germany Leader Award
2019 - Fellow of the American Academy of Arts and Sciences
2013 - Member of Academia Europaea
Member of the European Molecular Biology Organization (EMBO)
Thomas Jenuwein spends much of his time researching Histone methyltransferase, Histone lysine methylation, Histone code, Genetics and Histone methylation. His Histone methyltransferase study integrates concerns from other disciplines, such as Carcinogenesis, Histone H3 and EZH2. His Histone code study combines topics from a wide range of disciplines, such as Histone H2A and Histone H1.
Thomas Jenuwein mostly deals with Pericentric heterochromatin in his studies of Genetics. As a part of the same scientific study, Thomas Jenuwein usually deals with the Histone methylation, concentrating on Epigenomics and frequently concerns with Tandem repeat. He interconnects Chromatin, Epigenetics and Constitutive heterochromatin in the investigation of issues within Histone.
His primary areas of investigation include Histone methyltransferase, Genetics, Chromatin, Heterochromatin and Histone methylation. His Histone methyltransferase research is multidisciplinary, incorporating elements of Histone H2A, EZH2, Histone H3 and Histone code. His Histone H2A study incorporates themes from Histone H4 and Histone deacetylase 2.
Thomas Jenuwein focuses mostly in the field of Histone code, narrowing it down to topics relating to Histone H1 and, in certain cases, Chromatin remodeling. His research integrates issues of Histone, Epigenetics, DNA methylation and Cell biology in his study of Chromatin. His work deals with themes such as Molecular biology, Epigenomics and Chromatin immunoprecipitation, which intersect with Histone methylation.
The scientist’s investigation covers issues in Chromatin, Cell biology, Heterochromatin, Histone and Epigenetics. His Chromatin study is concerned with the field of Genetics as a whole. Thomas Jenuwein has researched Heterochromatin in several fields, including RNA and Gene expression.
His work on Histone methyltransferase as part of general Histone research is frequently linked to Midblastula, bridging the gap between disciplines. Thomas Jenuwein focuses mostly in the field of Epigenetics, narrowing it down to matters related to Regulation of gene expression and, in some cases, Cellular differentiation, Embryonic stem cell, Gene silencing and Human genome. He has included themes like Biophysics, Chromatin binding, ChIA-PET and Histone code in his Molecular biology study.
Thomas Jenuwein mainly investigates Chromatin, Genetics, Epigenetics, Epigenesis and Molecular biology. Histone H1 and Pericentric heterochromatin are subfields of Chromatin in which his conducts study. His research combines Computational biology and Genetics.
His Epigenetics research is multidisciplinary, incorporating perspectives in DNA methylation, Genomic imprinting and Computational epigenetics. His Epigenesis research includes elements of Transcriptome, Neuroscience and Mutant. His Molecular biology research integrates issues from Chromatin remodeling, Chromatin binding, Intron and Non-histone protein.
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Translating the Histone Code
Thomas Jenuwein;C. David Allis.
Regulation of chromatin structure by site-specific histone H3 methyltransferases
S Rea;F Eisenhaber;D O'Carroll;B D Strahl.
Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins.
Monika Lachner;Dónal O'Carroll;Stephen Rea;Karl Mechtler.
Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer
Mario F Fraga;Esteban Ballestar;Ana Villar-Garea;Manuel Boix-Chornet.
Nature Genetics (2005)
The molecular hallmarks of epigenetic control
C. David Allis;Thomas Jenuwein.
Nature Reviews Genetics (2016)
Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability.
Antoine H.F.M. Peters;Dónal O'Carroll;Harry Scherthan;Karl Mechtler.
Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing
Chryssa Kanellopoulou;Stefan A. Muljo;Andrew L. Kung;Shridar Ganesan.
Genes & Development (2005)
Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin
Bernhard Lehnertz;Yoshihide Ueda;Alwin A.H.A. Derijck;Ulrich Braunschweig.
Current Biology (2003)
Oncogene-induced senescence as an initial barrier in lymphoma development
Melanie Braig;Soyoung Lee;Christoph Loddenkemper;Cornelia Rudolph.
Partitioning and Plasticity of Repressive Histone Methylation States in Mammalian Chromatin
Antoine H.F.M. Peters;Stefan Kubicek;Karl Mechtler;Roderick J. O'Sullivan.
Molecular Cell (2003)
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