D-Index & Metrics Best Publications
Genetics
Germany
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics D-index 93 Citations 67,770 125 World Ranking 612 National Ranking 51

Research.com Recognitions

Awards & Achievements

2023 - Research.com Genetics in Germany Leader Award

2019 - Fellow of the American Academy of Arts and Sciences

2013 - Member of Academia Europaea

Member of the European Molecular Biology Organization (EMBO)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Epigenetics

Thomas Jenuwein spends much of his time researching Histone methyltransferase, Histone lysine methylation, Histone code, Genetics and Histone methylation. His Histone methyltransferase study integrates concerns from other disciplines, such as Carcinogenesis, Histone H3 and EZH2. His Histone code study combines topics from a wide range of disciplines, such as Histone H2A and Histone H1.

Thomas Jenuwein mostly deals with Pericentric heterochromatin in his studies of Genetics. As a part of the same scientific study, Thomas Jenuwein usually deals with the Histone methylation, concentrating on Epigenomics and frequently concerns with Tandem repeat. He interconnects Chromatin, Epigenetics and Constitutive heterochromatin in the investigation of issues within Histone.

His most cited work include:

  • Translating the Histone Code (7847 citations)
  • Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins. (2353 citations)
  • Regulation of chromatin structure by site-specific histone H3 methyltransferases (2262 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Histone methyltransferase, Genetics, Chromatin, Heterochromatin and Histone methylation. His Histone methyltransferase research is multidisciplinary, incorporating elements of Histone H2A, EZH2, Histone H3 and Histone code. His Histone H2A study incorporates themes from Histone H4 and Histone deacetylase 2.

Thomas Jenuwein focuses mostly in the field of Histone code, narrowing it down to topics relating to Histone H1 and, in certain cases, Chromatin remodeling. His research integrates issues of Histone, Epigenetics, DNA methylation and Cell biology in his study of Chromatin. His work deals with themes such as Molecular biology, Epigenomics and Chromatin immunoprecipitation, which intersect with Histone methylation.

He most often published in these fields:

  • Histone methyltransferase (49.23%)
  • Genetics (43.08%)
  • Chromatin (34.62%)

What were the highlights of his more recent work (between 2015-2021)?

  • Chromatin (34.62%)
  • Cell biology (23.08%)
  • Heterochromatin (33.08%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in Chromatin, Cell biology, Heterochromatin, Histone and Epigenetics. His Chromatin study is concerned with the field of Genetics as a whole. Thomas Jenuwein has researched Heterochromatin in several fields, including RNA and Gene expression.

His work on Histone methyltransferase as part of general Histone research is frequently linked to Midblastula, bridging the gap between disciplines. Thomas Jenuwein focuses mostly in the field of Epigenetics, narrowing it down to matters related to Regulation of gene expression and, in some cases, Cellular differentiation, Embryonic stem cell, Gene silencing and Human genome. He has included themes like Biophysics, Chromatin binding, ChIA-PET and Histone code in his Molecular biology study.

Between 2015 and 2021, his most popular works were:

  • The molecular hallmarks of epigenetic control (994 citations)
  • Trim28 Haploinsufficiency Triggers Bi-stable Epigenetic Obesity (107 citations)
  • Nuclear Architecture Organized by Rif1 Underpins the Replication-Timing Program (104 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Epigenetics

Thomas Jenuwein mainly investigates Chromatin, Genetics, Epigenetics, Epigenesis and Molecular biology. Histone H1 and Pericentric heterochromatin are subfields of Chromatin in which his conducts study. His research combines Computational biology and Genetics.

His Epigenetics research is multidisciplinary, incorporating perspectives in DNA methylation, Genomic imprinting and Computational epigenetics. His Epigenesis research includes elements of Transcriptome, Neuroscience and Mutant. His Molecular biology research integrates issues from Chromatin remodeling, Chromatin binding, Intron and Non-histone protein.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Translating the Histone Code

Thomas Jenuwein;C. David Allis.
Science (2001)

15708 Citations

Regulation of chromatin structure by site-specific histone H3 methyltransferases

S Rea;F Eisenhaber;D O'Carroll;B D Strahl.
Nature (2000)

3318 Citations

Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins.

Monika Lachner;Dónal O'Carroll;Stephen Rea;Karl Mechtler.
Nature (2001)

3271 Citations

Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer

Mario F Fraga;Esteban Ballestar;Ana Villar-Garea;Manuel Boix-Chornet.
Nature Genetics (2005)

2167 Citations

The molecular hallmarks of epigenetic control

C. David Allis;Thomas Jenuwein.
Nature Reviews Genetics (2016)

2153 Citations

Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability.

Antoine H.F.M. Peters;Dónal O'Carroll;Harry Scherthan;Karl Mechtler.
Cell (2001)

1862 Citations

Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing

Chryssa Kanellopoulou;Stefan A. Muljo;Andrew L. Kung;Shridar Ganesan.
Genes & Development (2005)

1566 Citations

Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin

Bernhard Lehnertz;Yoshihide Ueda;Alwin A.H.A. Derijck;Ulrich Braunschweig.
Current Biology (2003)

1401 Citations

Oncogene-induced senescence as an initial barrier in lymphoma development

Melanie Braig;Soyoung Lee;Christoph Loddenkemper;Cornelia Rudolph.
Nature (2005)

1349 Citations

Partitioning and Plasticity of Repressive Histone Methylation States in Mammalian Chromatin

Antoine H.F.M. Peters;Stefan Kubicek;Karl Mechtler;Roderick J. O'Sullivan.
Molecular Cell (2003)

1249 Citations

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