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Molecular Biology

D-Index
80
Citations
24696
World Ranking
995
National Ranking
81

Overview

Axel Imhof is affiliated with Ludwig-Maximilians-Universität München in Germany. Their research primarily focuses on the field of Biochemistry, Genetics, and Molecular Biology, with a notable concentration in Molecular Biology, Spectroscopy, Immunology, Physiology, and Plant Science as key subfields.

Their body of work extensively covers a range of topics including:

  • Genomics and Chromatin Dynamics
  • Epigenetics and DNA Methylation
  • RNA modifications and cancer
  • Advanced Proteomics Techniques and Applications
  • RNA and protein synthesis mechanisms
  • RNA Research and Splicing
  • Metabolomics and Mass Spectrometry Studies

Some of their recent significant papers include:

  • Systematic functional analysis of SARS-CoV-2 proteins uncovers viral innate immune antagonists and remaining vulnerabilities, 2021, Cell Reports
  • Endotoxinemia Accelerates Atherosclerosis Through Electrostatic Charge-Mediated Monocyte Adhesion, 2020, Circulation
  • Mechanisms governing the pioneering and redistribution capabilities of the non-classical pioneer PU.1, 2020, Nature Communications
  • Proteome dynamics at broken replication forks reveal a distinct ATM-directed repair response suppressing DNA double-strand break ubiquitination, 2021, Molecular Cell
  • Chromosome organization by a conserved condensin-ParB system in the actinobacterium Corynebacterium glutamicum, 2020, Nature Communications

Imhof's frequent collaborators include Ignasi Forné, Tobias Straub, Anuroop Venkateswaran Venkatasubramani, Wasim Aftab, and Andreas Schmidt. These collaborations indicate ongoing partnerships spanning various projects and publications.

Publication venues where they have frequently contributed are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Nucleic Acids Research
  • Cell Reports
  • Pancreatology

Best Publications

  • Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer

    Mario F Fraga;Esteban Ballestar;Ana Villar-Garea;Manuel Boix-Chornet

  • Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites.

    Birgit Czermin;Raffaella Melfi;Donna McCabe;Volker Seitz

  • Acetylation of general transcription factors by histone acetyltransferases

    Axel Imhof;Xiang-Jiao Yang;Vasily V Ogryzko;Yoshihiro Nakatani

  • Identification of a specific inhibitor of the histone methyltransferase SU(VAR)3-9

    Dorothea Greiner;Tiziana Bonaldi;Ragnhild Eskeland;Ernst Roemer;Ernst Roemer

  • Retraction: Histone methylation by the Drosophila epigenetic transcriptional regulator Ash1

    Christian Beisel;Axel Imhof;Jaime Greene;Elisabeth Kremmer

  • PTMs on H3 Variants before Chromatin Assembly Potentiate Their Final Epigenetic State

    Alejandra Loyola;Tiziana Bonaldi;Danièle Roche;Axel Imhof

  • Synergy between CD26/DPP-IV inhibition and G-CSF improves cardiac function after acute myocardial infarction

    Marc-Michael Zaruba;Hans Diogenes Theiss;Markus Vallaster;Ursula Mehl

  • Fast signals and slow marks: the dynamics of histone modifications

    Teresa K. Barth;Axel Imhof

  • Two distinct modes for propagation of histone PTMs across the cell cycle

    Constance Alabert;Teresa K. Barth;Nazaret Reverón-Gómez;Simone Sidoli

  • Connecting Threads: Epigenetics and Metabolism

    Sayako Katada;Axel Imhof;Axel Imhof;Paolo Sassone-Corsi

  • hMOF Histone Acetyltransferase Is Required for Histone H4 Lysine 16 Acetylation in Mammalian Cells

    Mikko Taipale;Stephen Rea;Karsten Richter;Ana Vilar

  • Secretome protein enrichment identifies physiological BACE1 protease substrates in neurons

    Peer-Hendrik Kuhn;Peer-Hendrik Kuhn;Katarzyna Koroniak;Sebastian Hogl;Alessio Colombo

  • PRMT6-mediated methylation of R2 in histone H3 antagonizes H3 K4 trimethylation.

    Dawin Hyllus;Claudia Stein;Kristin Schnabel;Emile Schiltz

  • Replication stress interferes with histone recycling and predeposition marking of new histones.

    Zuzana Jasencakova;Annette N.D. Scharf;Katrine Ask;Armelle Corpet

  • Toll-like Receptor Signaling Rewires Macrophage Metabolism and Promotes Histone Acetylation via ATP-Citrate Lyase.

    Mario A. Lauterbach;Jasmin E. Hanke;Magdalini Serefidou;Matthew S.J. Mangan;Matthew S.J. Mangan

  • Phosphorylation of histone H3T6 by PKCβ I controls demethylation at histone H3K4

    Eric Metzger;Axel Imhof;Dharmeshkumar Patel;Philip Kahl

  • Cloning and characterization of a second AP-2 transcription factor: AP-2 beta

    Markus Moser;Axel Imhof;Armin Pscherer;Reinhard Bauer

  • Transcriptional activation by Myc is under negative control by the transcription factor AP-2.

    Stefan Gaubatz;Axel Imhof;Roland Dosch;Oliver Werner

  • Physical and functional association of SU(VAR)3-9 and HDAC1 in Drosophila.

    Birgit Czermin;Gunnar Schotta;Bastian B Hülsmann;Alexander Brehm

  • The HP1α–CAF1–SetDB1-containing complex provides H3K9me1 for Suv39-mediated K9me3 in pericentric heterochromatin

    Alejandra Loyola;Alejandra Loyola;Alejandra Loyola;Hideaki Tagami;Tiziana Bonaldi;Danièle Roche

Frequent Co-Authors

Peter B. Becker
Peter B. Becker Ludwig-Maximilians-Universität München
Tiziana Bonaldi
Tiziana Bonaldi European Institute of Oncology
Tobias Straub
Tobias Straub Ludwig-Maximilians-Universität München
Jesper Tegnér
Jesper Tegnér King Abdullah University of Science and Technology
Elisabeth Kremmer
Elisabeth Kremmer Max Planck Society
Geneviève Almouzni
Geneviève Almouzni Institute Curie
Roland Schüle
Roland Schüle University of Freiburg
Gernot Längst
Gernot Längst University of Regensburg
Johan A. Westerhuis
Johan A. Westerhuis University of Amsterdam
Paolo Sassone-Corsi
Paolo Sassone-Corsi University of California, Irvine

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