2026 Stefan F. Lichtenthaler: Biology and Biochemistry Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Biology and Biochemistry	67	8251	7612	603	571	231	15316

Overview

Stefan F. Lichtenthaler is affiliated with the German Center for Neurodegenerative Diseases in Germany. Their research contributions primarily focus on the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with notable work in subfields such as Molecular Biology, Neurology, Physiology, Oncology, and Cell Biology.

Their main topics of research include:

Alzheimer's disease research and treatments
Neuroinflammation and Neurodegeneration Mechanisms
Cell Adhesion Molecules Research
Cellular transport and secretion
Peptidase Inhibition and Analysis
Advanced Proteomics Techniques and Applications
Neuroscience and Neuropharmacology Research

Stefan F. Lichtenthaler has published extensively in several prestigious scientific venues. Their most frequent publication outlets include:

bioRxiv (Cold Spring Harbor Laboratory), with 23 publications
Nature Communications, 9 publications
Journal of Biological Chemistry, 8 publications
Molecular Neurodegeneration, 5 publications
International Journal of Molecular Sciences, 4 publications

Some recent papers authored or co-authored by them include:

The substrate repertoire of γ-secretase/presenilin (2020), Seminars in Cell and Developmental Biology
Pro-inflammatory activation following demyelination is required for myelin clearance and oligodendrogenesis (2020), The Journal of Experimental Medicine
Fibrillar Aβ triggers microglial proteome alterations and dysfunction in Alzheimer mouse models (2020), eLife
The case for low-level BACE1 inhibition for the prevention of Alzheimer disease (2021), Nature Reviews Neurology
ADAM10 and ADAM17 promote SARS-CoV-2 cell entry and spike protein-mediated lung cell fusion (2022), EMBO Reports

Stefan F. Lichtenthaler has collaborated frequently with several researchers, including:

Stephan A. Müller
Christian Haass
Johanna Tüshaus
Sabina Tahirović
Carl Blobel

Best Publications

ADAM10 is the physiologically relevant, constitutive α-secretase of the amyloid precursor protein in primary neurons

Peer‐Hendrik Kuhn;Huanhuan Wang;Bastian Dislich;Bastian Dislich;Alessio Colombo;Alessio Colombo

788
Citations
Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE.

Samira Parhizkar;Thomas Arzberger;Matthias Brendel;Gernot Kleinberger

555
Citations
Phosphorylation of the Translation Initiation Factor eIF2α Increases BACE1 Levels and Promotes Amyloidogenesis

Tracy O'Connor;Katherine Rose Sadleir;Erika Maus;Rodney A. Velliquette

474
Citations
Function, therapeutic potential and cell biology of BACE proteases: current status and future prospects.

Robert Vassar;Peer Hendrik Kuhn;Peer Hendrik Kuhn;Christian Haass;Christian Haass;Matthew E. Kennedy;Matthew E. Kennedy

374
Citations
γ-secretase directly sheds the survival receptor BCMA from plasma cells

Sarah A. Laurent;Franziska S. Hoffmann;Peer-Hendrik Kuhn;Qingyu Cheng

367
Citations
The Cell Adhesion Protein P-selectin Glycoprotein Ligand-1 Is a Substrate for the Aspartyl Protease BACE1

Stefan F Lichtenthaler;Diana Ines Dominguez;Gil G Westmeyer;Karina Reiss

353
Citations
Secretome protein enrichment identifies physiological BACE1 protease substrates in neurons

Peer-Hendrik Kuhn;Peer-Hendrik Kuhn;Katarzyna Koroniak;Sebastian Hogl;Alessio Colombo

347
Citations
Regulated intramembrane proteolysis – lessons from amyloid precursor protein processing

Stefan F. Lichtenthaler;Christian Haass;Harald Steiner

323
Citations
Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity

Caroline Fecher;Caroline Fecher;Caroline Fecher;Laura Trovò;Laura Trovò;Stephan A. Müller;Stephan A. Müller;Nicolas Snaidero;Nicolas Snaidero

322
Citations
Mechanism of the cleavage specificity of Alzheimer’s disease γ-secretase identified by phenylalanine-scanning mutagenesis of the transmembrane domain of the amyloid precursor protein

Stefan F. Lichtenthaler;Rong Wang;Heike Grimm;Sacha N. Uljon

322
Citations
An Alzheimer‐associated TREM2 variant occurs at the ADAM cleavage site and affects shedding and phagocytic function

Kai Schlepckow;Gernot Kleinberger;Akio Fukumori;Regina Feederle

308
Citations
Transcriptional and translational regulation of BACE1 expression--implications for Alzheimer's disease.

Steffen Rossner;Magdalena Sastre;Krystyn Bourne;Stefan F Lichtenthaler

266
Citations
Proteolytic ectodomain shedding of membrane proteins in mammals—hardware, concepts, and recent developments

Stefan F Lichtenthaler;Stefan F Lichtenthaler;Marius K Lemberg;Regina Fluhrer;Regina Fluhrer

257
Citations
The alpha secretase ADAM10: A metalloprotease with multiple functions in the brain.

Paul Saftig;Stefan F. Lichtenthaler;Stefan F. Lichtenthaler

249
Citations
Regulated intramembrane proteolysis of the interleukin-1 receptor II by alpha-, beta-, and gamma-secretase.

Peer-Hendrik Kuhn;Els Marjaux;Axel Imhof;Bart De Strooper

241
Citations
Alpha-secretase in Alzheimer's disease: molecular identity, regulation and therapeutic potential

Stefan F. Lichtenthaler

241
Citations
The E3 Ligase Parkin Maintains Mitochondrial Integrity by Increasing Linear Ubiquitination of NEMO

Anne Kathrin Müller-Rischart;Anna Pilsl;Patrick Beaudette;Maria Patra

233
Citations
The FTLD risk factor TMEM106B and MAP6 control dendritic trafficking of lysosomes

Benjamin M Schwenk;Christina M Lang;Sebastian Hogl;Sabina Tahirovic

206
Citations
Expression of the Alzheimer protease BACE1 is suppressed via its 5'-untranslated region

Sven Lammich;Susanne Schöbel;Ann-Katrin Zimmer;Stefan F Lichtenthaler

172
Citations
BACE1 Physiological Functions May Limit Its Use as Therapeutic Target for Alzheimer's Disease.

Soraia Barão Lourenco Barao;Diederik Moechars;Stefan F Lichtenthaler;Stefan F Lichtenthaler;Bart De Strooper;Bart De Strooper

169
Citations