Stefan F. Lichtenthaler focuses on Amyloid precursor protein secretase, Amyloid precursor protein, Proteases, Cell biology and Neuroscience. His study looks at the relationship between Amyloid precursor protein secretase and topics such as Protease, which overlap with Pathogenesis, Transmembrane protein, Untranslated region and Messenger RNA. The Alpha secretase research Stefan F. Lichtenthaler does as part of his general Amyloid precursor protein study is frequently linked to other disciplines of science, such as Cognitive decline, therefore creating a link between diverse domains of science.
His Proteases study combines topics in areas such as Cell signaling, Neuregulin 1 and Ectodomain. His Cell biology study combines topics from a wide range of disciplines, such as Motor neuron, Proteomics, Neurodegeneration and Zebrafish. His studies deal with areas such as Mutation and Amyotrophic lateral sclerosis as well as Neuroscience.
Stefan F. Lichtenthaler mainly focuses on Cell biology, Amyloid precursor protein, Biochemistry, Ectodomain and Amyloid precursor protein secretase. His study in Cell biology is interdisciplinary in nature, drawing from both Cell, Proteomics, Neurodegeneration, Transmembrane protein and Disintegrin. His Amyloid precursor protein research is multidisciplinary, incorporating perspectives in Amyloid beta, ADAM10 and Neuroscience.
His Ectodomain research is multidisciplinary, relying on both Paracrine signalling, Homeostasis, Proteases, Signal transduction and Presenilin. His work focuses on many connections between Proteases and other disciplines, such as Protease, that overlap with his field of interest in Pathogenesis and Disease. His Amyloid precursor protein secretase research includes themes of Beta and Alpha secretase.
His primary areas of investigation include Cell biology, Ectodomain, Cell, Microglia and Neuroscience. His research integrates issues of Receptor and Proteomics, Quantitative proteomics in his study of Cell biology. His Ectodomain research incorporates themes from Amino acid, Cleavage, Proteases and Disintegrin, ADAM10.
The Cell study combines topics in areas such as Secretory protein and Neuroinflammation. The study incorporates disciplines such as Synaptic plasticity and Proteome in addition to Neuroscience. His Amyloid beta research includes elements of Gamma secretase, Amyloid precursor protein secretase and In vivo.
Cell biology, Neuroinflammation, Cleavage, Microglia and Ectodomain are his primary areas of study. The study incorporates disciplines such as Cell, Zebrafish, Innate immune system, Macrophage and Spinal cord in addition to Cell biology. His biological study spans a wide range of topics, including Secretory protein, Proteomics, Quantitative proteomics, Secretomics and Cell type.
Cleavage is the subject of his research, which falls under Biochemistry. His Microglia research includes elements of Phagocytosis, Potential biomarkers, Phenotype, Aβ deposition and Functional studies. The Ectodomain study combines topics in areas such as Protein degradation, Protein subunit, Presenilin, Intramembrane protease and Transmembrane domain.
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Function, therapeutic potential and cell biology of BACE proteases: current status and future prospects.
Robert Vassar;Peer Hendrik Kuhn;Peer Hendrik Kuhn;Christian Haass;Christian Haass;Matthew E. Kennedy;Matthew E. Kennedy.
Journal of Neurochemistry (2014)
Regulated intramembrane proteolysis – lessons from amyloid precursor protein processing
Stefan F. Lichtenthaler;Christian Haass;Harald Steiner.
Journal of Neurochemistry (2011)
Transcriptional and translational regulation of BACE1 expression--implications for Alzheimer's disease.
Steffen Rossner;Magdalena Sastre;Krystyn Bourne;Stefan F Lichtenthaler.
Progress in Neurobiology (2006)
Regulated Intramembrane Proteolysis of the Interleukin-1 Receptor II by α-, β-, and γ-Secretase
Peer-Hendrik Kuhn;Els Marjaux;Axel Imhof;Bart De Strooper.
Journal of Biological Chemistry (2007)
Alpha-secretase in Alzheimer's disease: molecular identity, regulation and therapeutic potential
Stefan F. Lichtenthaler.
Journal of Neurochemistry (2011)
The alpha secretase ADAM10: A metalloprotease with multiple functions in the brain.
Paul Saftig;Stefan F. Lichtenthaler;Stefan F. Lichtenthaler.
Progress in Neurobiology (2015)
Expression of the Alzheimer protease BACE1 is suppressed via its 5'-untranslated region
Sven Lammich;Susanne Schöbel;Ann-Katrin Zimmer;Stefan F Lichtenthaler.
EMBO Reports (2004)
Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE.
Samira Parhizkar;Thomas Arzberger;Matthias Brendel;Gernot Kleinberger.
Nature Neuroscience (2019)
γ-secretase directly sheds the survival receptor BCMA from plasma cells
Sarah A. Laurent;Franziska S. Hoffmann;Peer-Hendrik Kuhn;Qingyu Cheng.
Nature Communications (2015)
Dimerization of β-Site β-Amyloid Precursor Protein-cleaving Enzyme
Gil G. Westmeyer;Michael Willem;Stefan F. Lichtenthaler;Glenn Lurman.
Journal of Biological Chemistry (2004)
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Publications: 21
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