Tobias Hartmann

Overview

Best Publications

• Simvastatin strongly reduces levels of Alzheimer's disease β-amyloid peptides Aβ42 and Aβ40 in vitro and in vivo

  K. Fassbender;M. Simons;C. Bergmann;M. Stroick

  1497
  Citations

• Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides.

  Tobias Hartmann;Sophie C. Bieger;Babara Brühl;Pentti J. Tienari

  959
  Citations

• Analysis of Heterogeneous βA4 Peptides in Human Cerebrospinal Fluid and Blood by a Newly Developed Sensitive Western Blot Assay

  Nobuo Ida;Tobias Hartmann;Johannes Pantel;Johannes Schröder

  621
  Citations

• Treatment with simvastatin in normocholesterolemic patients with Alzheimer's disease: A 26-week randomized, placebo-controlled, double-blind trial.

  Mikael Simons;Frank Schwärzler;Dieter Lütjohann;Klaus Von Bergmann

  578
  Citations

• Aggregation promoting C-terminal truncation of α-synuclein is a normal cellular process and is enhanced by the familial Parkinson's disease-linked mutations

  Wenxue Li;Neva West;Emanuela Colla;Olga Pletnikova

  565
  Citations

• Regulation of cholesterol and sphingomyelin metabolism by amyloid-beta and presenilin.

  Marcus O W Grimm;Heike S Grimm;Andreas J Pätzold;Eva G Zinser

  527
  Citations

• Amyloidogenicity of beta A4 and beta A4-bearing amyloid protein precursor fragments by metal-catalyzed oxidation.

  T Dyrks;E Dyrks;T Hartmann;C Masters

  487
  Citations

• TLR2 Is a Primary Receptor for Alzheimer’s Amyloid β Peptide To Trigger Neuroinflammatory Activation

  Shirong Liu;Yang Liu;Wenlin Hao;Lisa Wolf

  484
  Citations

• The LPS receptor (CD14) links innate immunity with Alzheimer's disease.

  K. Fassbender;S. Walter;S. Kühl;S. Kühl;R. Landmann

  421
  Citations

• TNFα plus IFNγ induce the production of Alzheimer β-amyloid peptides and decrease the secretion of APPs

  I. Blasko;F. Marx;E. Steiner;T. Hartmann

  404
  Citations

• Impact of different saturated fatty acid, polyunsaturated fatty acid and cholesterol containing diets on beta-amyloid accumulation in APP/PS1 transgenic mice

  M. Oksman;H. Iivonen;E. Hogyes;Z. Amtul

  376
  Citations

• Inhibition of Intracellular Cholesterol Transport Alters Presenilin Localization and Amyloid Precursor Protein Processing in Neuronal Cells

  Heiko Runz;Jens Rietdorf;Inge Tomic;Marina de Bernard

  294
  Citations

• Cerebrospinal fluid Aβ42 is increased early in sporadic Alzheimer's disease and declines with disease progression

  Malene Jensen;Johannes Schröder;Mari Blomberg;Benita Engvall

  292
  Citations

• Alzheimer's disease: the lipid connection.

  Tobias Hartmann;Johannna Kuchenbecker;Marcus O. W. Grimm

  272
  Citations

• Altered Gut Microbiome Composition and Tryptic Activity of the 5xFAD Alzheimer's Mouse Model.

  Carolin Brandscheid;Florian Schuck;Sven Reinhardt;Karl-Herbert Schäfer

  264
  Citations

• Key Factors in Alzheimer's Disease: β‐amyloid Precursor Protein Processing, Metabolism and Intraneuronal Transport

  Thomas A. Bayer;Oliver Wirths;Katalin Majtényi;Tobias Hartmann

  254
  Citations

• Docosahexaenoic Acid Reduces Amyloid β Production via Multiple Pleiotropic Mechanisms

  Marcus O.W. Grimm;Johanna Kuchenbecker;Sven Grösgen;Verena K. Burg

  240
  Citations

• Innate immune receptor expression in normal brain aging

  M. Letiembre;W. Hao;Y. Liu;S. Walter

  228
  Citations

• Cerebrospinal fluid 24S-hydroxycholesterol is increased in patients with Alzheimer's disease compared to healthy controls

  Peter Schönknecht;Dieter Lütjohann;Johannes Pantel;Habertus Bardenheuer

  207
  Citations

• Non-Aβ Component of Alzheimer's Disease Amyloid (NAC) Revisited: NAC and α-Synuclein Are Not Associated with Aβ Amyloid

  Janetta G. Culvenor;Catriona A. McLean;Sally Cutt;Bruce C.V. Campbell

  203
  Citations