H-Index & Metrics Best Publications

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Immunology D-index 95 Citations 31,919 218 World Ranking 341 National Ranking 213
Medicine D-index 105 Citations 37,942 264 World Ranking 3024 National Ranking 1741

Research.com Recognitions

Awards & Achievements

2004 - National Institutes of Health Director's Pioneer Award

Member of the Association of American Physicians

Overview

What is he best known for?

The fields of study he is best known for:

  • Immune system
  • Gene
  • Internal medicine

His scientific interests lie mostly in Immunology, T cell, Virology, CD8 and Immune system. He combines subjects such as Internal medicine, Acquired immunodeficiency syndrome and CD38 with his study of Immunology. The T cell study combines topics in areas such as Cytotoxic T cell, Interleukin 17, Molecular biology and Antigen.

His Lymphatic system research extends to Virology, which is thematically connected. His studies deal with areas such as Severe combined immunodeficiency, In vivo, Endogeny and Thymic Tissue as well as CD8. His Immune system study combines topics in areas such as Inflammation and Disease.

His most cited work include:

  • The American College of Rheumatology nomenclature and case definitions for neuropsychiatric lupus syndromes (1362 citations)
  • The SCID-hu mouse: murine model for the analysis of human hematolymphoid differentiation and function. (1323 citations)
  • Maternal alloantigens promote the development of tolerogenic fetal regulatory T cells in utero. (612 citations)

What are the main themes of his work throughout his whole career to date?

Joseph M. McCune mainly focuses on Immunology, Virology, T cell, Immune system and CD8. Joseph M. McCune interconnects Cytotoxic T cell and Haematopoiesis in the investigation of issues within Immunology. Joseph M. McCune has researched Virology in several fields, including Acquired immunodeficiency syndrome and In vivo.

His work carried out in the field of T cell brings together such families of science as Molecular biology and Antigen. His Immune system research incorporates themes from Fetus and Immunopathology. His CD8 study incorporates themes from Cell biology, Flow cytometry and CD38.

He most often published in these fields:

  • Immunology (64.98%)
  • Virology (34.07%)
  • T cell (24.92%)

What were the highlights of his more recent work (between 2012-2021)?

  • Immunology (64.98%)
  • T cell (24.92%)
  • Cytotoxic T cell (14.83%)

In recent papers he was focusing on the following fields of study:

Joseph M. McCune mostly deals with Immunology, T cell, Cytotoxic T cell, Immune system and Virology. Immunology and Fetus are commonly linked in his work. His T cell course of study focuses on Peripheral blood mononuclear cell and Programmed cell death.

His Cytotoxic T cell research incorporates elements of Senescence and Flow cytometry. His research integrates issues of Kynurenine pathway, Immunophenotyping and Microbiology in his study of Immune system. His study in the field of Viral replication also crosses realms of Persistence.

Between 2012 and 2021, his most popular works were:

  • Dysbiosis of the Gut Microbiota Is Associated with HIV Disease Progression and Tryptophan Catabolism (403 citations)
  • HIV-infected individuals with low CD4/CD8 ratio despite effective antiretroviral therapy exhibit altered T cell subsets, heightened CD8+ T cell activation, and increased risk of non-AIDS morbidity and mortality. (326 citations)
  • International AIDS Society global scientific strategy: towards an HIV cure 2016 (268 citations)

In his most recent research, the most cited papers focused on:

  • Immune system
  • Gene
  • Internal medicine

Joseph M. McCune spends much of his time researching Immunology, Virology, T cell, Immune system and CD8. His Immunology research includes themes of Cytotoxic T cell and Disease. Joseph M. McCune does research in Virology, focusing on Virus specifically.

His T cell research is multidisciplinary, relying on both Phenotype, Viremia, In situ hybridization and B cell. His study in Immune system is interdisciplinary in nature, drawing from both Kynurenine pathway, Cellular differentiation, Tryptophan, Microbiology and Immunophenotyping. His biological study spans a wide range of topics, including Internal medicine, Cohort study and CD38.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The SCID-hu mouse: murine model for the analysis of human hematolymphoid differentiation and function.

JM McCune;R Namikawa;H Kaneshima;LD Shultz.
Science (1988)

1656 Citations

The American College of Rheumatology nomenclature and case definitions for neuropsychiatric lupus syndromes

Matthew H. Liang;Michael Corzillius;Sang Cheol Bae;Robert A. Lew.
Arthritis & Rheumatism (1999)

1243 Citations

Virologic and immunologic consequences of discontinuing combination antiretroviral-drug therapy in HIV-infected patients with detectable viremia.

Steven G. Deeks;Terri Wrin;Teri Liegler;Rebecca Hoh.
The New England Journal of Medicine (2001)

833 Citations

Endoproteolytic cleavage of gp160 is required for the activation of human immunodeficiency virus

Joseph M. McCune;Linda B. Rabin;Mark B. Feinberg;Miriam Lieberman.
Cell (1988)

750 Citations

Directly measured kinetics of circulating T lymphocytes in normal and HIV-1-infected humans

M Hellerstein;M B Hanley;D Cesar;S Siler.
Nature Medicine (1999)

726 Citations

The dynamics of CD4 + T-cell depletion in HIV disease

Joseph M. McCune.
Nature (2001)

722 Citations

Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection

R. Brad Jones;Lishomwa C Ndhlovu;Jason D. Barbour;Prameet M. Sheth.
Journal of Experimental Medicine (2008)

722 Citations

Maternal alloantigens promote the development of tolerogenic fetal regulatory T cells in utero.

Jeff E. Mold;Jakob Michaëlsson;Trevor D. Burt;Marcus O. Muench.
Science (2008)

706 Citations

Relationship between T Cell Activation and CD4+ T Cell Count in HIV-Seropositive Individuals with Undetectable Plasma HIV RNA Levels in the Absence of Therapy

Peter W. Hunt;Jason Brenchley;Elizabeth Sinclair;Joseph M. McCune.
The Journal of Infectious Diseases (2008)

686 Citations

Increased Production of IL-7 Accompanies HIV-1-mediated T-cell Depletion: Implications for T-cell Homeostasis

Laura A. Napolitano;Robert M. Grant;Steven G. Deeks;Diane Schmidt.
Nature Medicine (2001)

617 Citations

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