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Immunology

D-Index
57
Citations
12717
World Ranking
3612
National Ranking
1671

Overview

Mirko Paiardini is affiliated with Emory University in the United States and works primarily in the fields of immunology, microbiology, and medicine. Their research focuses extensively on immunology, infectious diseases, and virology, with additional work in epidemiology and molecular biology.

Their research topics cover various aspects of HIV and COVID-19, including HIV research and treatment, immune cell function and interaction, T-cell and B-cell immunology, HIV/AIDS interventions, cytomegalovirus and herpesvirus research, and SARS-CoV-2 and COVID-19 studies.

Mirko Paiardini has published in numerous scientific venues, frequently contributing to the Journal of Virology, PLoS Pathogens, bioRxiv (Cold Spring Harbor Laboratory), UNC Libraries, and Nature Communications.

Recent publications include:

  • "Research priorities for an HIV cure: International AIDS Society Global Scientific Strategy 2021" (2021, Nature Medicine)
  • "Baricitinib treatment resolves lower-airway macrophage inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques" (2020, Cell)
  • "Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8+ cells" (2020, Nature)
  • "Recommendations for measuring HIV reservoir size in cure-directed clinical trials" (2020, Nature Medicine)
  • "CTLA-4 and PD-1 dual blockade induces SIV reactivation without control of rebound after antiretroviral therapy interruption" (2020, Nature Medicine)

Mirko Paiardini frequently collaborates with several researchers, including Guido Silvestri, Justin Harper, Steven E. Bosinger, Deanna A. Kulpa, and Jacob D. Estes.

Best Publications

  • Nonpathogenic SIV infection of sooty mangabeys is characterized by limited bystander immunopathology despite chronic high-level viremia.

    Guido Silvestri;Donald L. Sodora;Richard A. Koup;Richard A. Koup;Mirko Paiardini

  • Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections

    Jason M. Brenchley;Mirko Paiardini;Kenneth S. Knox;Kenneth S. Knox;Ava I. Asher

  • Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections

    Jacob D. Estes;Levelle D. Harris;Nichole R. Klatt;Brian Tabb

  • HIV-associated chronic immune activation

    Mirko Paiardini;Michaela Müller-Trutwin

  • Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeys

    Steven E. Bosinger;Qingsheng Li;Shari N. Gordon;Nichole R. Klatt

  • Research priorities for an HIV cure: International AIDS Society Global Scientific Strategy 2021.

    Steven G. Deeks;Nancie Archin;Paula Cannon;Simon Collins

  • Natural SIV Hosts: Showing AIDS the Door

    Ann Chahroudi;Ann Chahroudi;Steven Bosinger;Thomas Howerton Vanderford;Mirko Paiardini;Mirko Paiardini

  • Severe Depletion of Mucosal CD4+ T Cells in AIDS-Free Simian Immunodeficiency Virus-Infected Sooty Mangabeys

    Shari N. Gordon;Nichole R. Klatt;Nichole R. Klatt;Steven E. Bosinger;Jason M. Brenchley

  • Downregulation of Robust Acute Type I Interferon Responses Distinguishes Nonpathogenic Simian Immunodeficiency Virus (SIV) Infection of Natural Hosts from Pathogenic SIV Infection of Rhesus Macaques

    Levelle D. Harris;Brian Tabb;Donald L. Sodora;Mirko Paiardini

  • Understanding the benign nature of SIV infection in natural hosts

    Guido Silvestri;Mirko Paiardini;Ivona Pandrea;Michael M. Lederman

  • Loss of CD127 Expression Defines an Expansion of Effector CD8+ T Cells in HIV-Infected Individuals

    Mirko Paiardini;Barbara Cervasi;Barbara Cervasi;Helmut Albrecht;Alagarraju Muthukumar

  • Loss of mucosal CD103+ DCs and IL-17+ and IL-22+ lymphocytes is associated with mucosal damage in SIV infection.

    Nichole R. Klatt;Jacob D. Estes;Xiaoyong Sun;Alexandra M. Ortiz;Alexandra M. Ortiz

  • Low levels of SIV infection in sooty mangabey central memory CD4 + T cells are associated with limited CCR5 expression

    Mirko Paiardini;Barbara Cervasi;Barbara Cervasi;Elane Reyes-Aviles;Luca Micci;Luca Micci

  • CD8+ Lymphocytes Are Required for Maintaining Viral Suppression in SIV-Infected Macaques Treated with Short-Term Antiretroviral Therapy

    Emily K. Cartwright;Lori Spicer;S. Abigail Smith;David Lee

  • Baricitinib treatment resolves lower-airway macrophage inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques.

    Timothy N. Hoang;Maria Pino;Arun K. Boddapati;Elise G. Viox

  • Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8+ cells.

    Julia Bergild McBrien;Maud Mavigner;Lavinia Franchitti;S. Abigail Smith

  • CD8+ Lymphocytes Control Viral Replication in SIVmac239-Infected Rhesus Macaques without Decreasing the Lifespan of Productively Infected Cells

    Nichole R. Klatt;Nichole R. Klatt;Emi Shudo;Alex M. Ortiz;Jessica C. Engram

  • Mucosal immune dysfunction in AIDS pathogenesis.

    Mirko Paiardini;Ian Frank;Ivona Pandrea;Cristian Apetrei

  • CTLA-4+PD-1− Memory CD4+ T Cells Critically Contribute to Viral Persistence in Antiretroviral Therapy-Suppressed, SIV-Infected Rhesus Macaques

    Colleen S. McGary;Claire Deleage;Justin Harper;Luca Micci

  • CD127 and CD25 Expression Defines CD4+ T Cell Subsets That Are Differentially Depleted during HIV Infection

    Richard M. Dunham;Barbara Cervasi;Jason M. Brenchley;Helmut Albrecht

  • Disruption of Intestinal CD4+ T Cell Homeostasis Is a Key Marker of Systemic CD4+ T Cell Activation in HIV-Infected Individuals

    Shari N. Gordon;Barbara Cervasi;Barbara Cervasi;Pamela Odorizzi;Randee Silverman

Frequent Co-Authors

Guido Silvestri
Guido Silvestri Emory University
Jacob D. Estes
Jacob D. Estes Oregon Health & Science University
Ann Chahroudi
Ann Chahroudi Emory University
Steven E. Bosinger
Steven E. Bosinger Emory University
Donald L. Sodora
Donald L. Sodora Seattle Children's Hospital
Mauro Magnani
Mauro Magnani University of Urbino
Jason M. Brenchley
Jason M. Brenchley National Institute of Allergy and Infectious Diseases
Cristian Apetrei
Cristian Apetrei University of Pittsburgh
Cynthia A. Derdeyn
Cynthia A. Derdeyn University of Washington
Ronald G. Collman
Ronald G. Collman University of Pennsylvania

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