World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
70
Citations
17189
World Ranking
2422
National Ranking
1161

Medicine

D-Index
70
Citations
17189
World Ranking
20105
National Ranking
10008

Overview

Jason M. Brenchley is affiliated with the National Institute of Allergy and Infectious Diseases in the United States. Their research primarily focuses onMedicine and Immunology and Microbiology, with particular emphasis on several subfields including Infectious Diseases, Immunology, Epidemiology, Virology, and Molecular Biology.

The scientist's work covers a range of topics centered on HIV Research and Treatment, Immune Cell Function and Interaction, Gut microbiota and health, HIV/AIDS Research and Interventions, Cytomegalovirus and herpesvirus research, Pneumocystis jirovecii pneumonia detection and treatment, as well as T-cell and B-cell Immunology.

Jason M. Brenchley has contributed to numerous publications in various academic venues. The most frequent publication platforms include bioRxiv (Cold Spring Harbor Laboratory) with 9 publications, PLoS Pathogens with 8, Nature Communications and JCI Insight each with 3, and Journal of Virology also with 3 papers.

  • HIV-associated gut dysbiosis is independent of sexual practice and correlates with noncommunicable diseases, 2020, Nature Communications
  • Discovery of several thousand highly diverse circular DNA viruses, 2020, eLife
  • HIV-1-induced cytokines deplete homeostatic innate lymphoid cells and expand TCF7-dependent memory NK cells, 2020, Nature Immunology
  • Translocated microbiome composition determines immunological outcome in treated HIV infection, 2021, Cell
  • TCF-1 regulates HIV-specific CD8+ T cell expansion capacity, 2020, JCI Insight

Frequent collaborators in their research include Alexandra M. Ortiz, Andrew R. Rahmberg, Jacob K. Flynn, Kelsie Brooks, and Vanessa M. Hirsch.

Best Publications

  • Impaired T H 17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome

    Joshua D. Milner;Jason M. Brenchley;Jason M. Brenchley;Arian Laurence;Alexandra F. Freeman

  • Microbial translocation across the GI tract.

    Jason M. Brenchley;Daniel C. Douek

  • T Cell Responses to Whole SARS Coronavirus in Humans

    Chris Ka Fai Li;Hao Wu;Huiping Yan;Shiwu Ma

  • Non-classical Immunity Controls Microbiota Impact on Skin Immunity and Tissue Repair.

    Jonathan L. Linehan;Oliver J. Harrison;Seong Ji Han;Allyson L. Byrd;Allyson L. Byrd

  • Acquisition of direct antiviral effector functions by CMV-specific CD4+ T lymphocytes with cellular maturation

    Joseph P. Casazza;Michael R. Betts;David A. Price;Melissa L. Precopio

  • CD4 T follicular helper cell dynamics during SIV infection

    Constantinos Petrovas;Takuya Yamamoto;Michael Y. Gerner;Kristin L. Boswell

  • Toll-Like Receptor Ligands Modulate Dendritic Cells to Augment Cytomegalovirus- and HIV-1-Specific T Cell Responses

    Karin Loré;Michael R. Betts;Jason M. Brenchley;Janaki Kuruppu

  • Increased tissue factor expression on circulating monocytes in chronic HIV infection: relationship to in vivo coagulation and immune activation

    Nicholas T. Funderburg;Elizabeth Mayne;Scott F. Sieg;Robert Asaad

  • HIV-Specific Cytolytic CD4 T Cell Responses During Acute HIV Infection Predict Disease Outcome

    Damien Z. Soghoian;Heiko Jessen;Michael Flanders;Kailan Sierra-Davidson

  • Functional leukemia-associated antigen-specific memory CD8+ T cells exist in healthy individuals and in patients with chronic myelogenous leukemia before and after stem cell transplantation.

    Katayoun Rezvani;Matthias Grube;Matthias Grube;Jason M. Brenchley;Jason M. Brenchley;Giuseppe Sconocchia;Giuseppe Sconocchia

  • A Critical Role for STAT3 Transcription Factor Signaling in the Development and Maintenance of Human T Cell Memory

    Andrea M. Siegel;Jennifer Heimall;Alexandra F. Freeman;Amy P. Hsu

  • Severe Depletion of Mucosal CD4+ T Cells in AIDS-Free Simian Immunodeficiency Virus-Infected Sooty Mangabeys

    Shari N. Gordon;Nichole R. Klatt;Nichole R. Klatt;Steven E. Bosinger;Jason M. Brenchley

  • Progressive CD4+ central–memory T cell decline results in CD4+ effector–memory insufficiency and overt disease in chronic SIV infection

    Afam A. Okoye;Martin Meier-Schellersheim;Jason M. Brenchley;Shoko I Hagen

  • Downregulation of Robust Acute Type I Interferon Responses Distinguishes Nonpathogenic Simian Immunodeficiency Virus (SIV) Infection of Natural Hosts from Pathogenic SIV Infection of Rhesus Macaques

    Levelle D. Harris;Brian Tabb;Donald L. Sodora;Mirko Paiardini

  • Pathogenic Simian Immunodeficiency Virus Infection Is Associated with Expansion of the Enteric Virome

    Scott A. Handley;Larissa B. Thackray;Guoyan Zhao;Rachel Presti

  • Altered balance between Th17 and Th1 cells at mucosal sites predicts AIDS progression in simian immunodeficiency virus-infected macaques

    V Cecchinato;C J Trindade;A Laurence;J M Heraud;J M Heraud

  • Acute loss of intestinal CD4+ T cells is not predictive of simian immunodeficiency virus virulence.

    Ivona V. Pandrea;Rajeev Gautam;Ruy M. Ribeiro;Jason M. Brenchley

  • Beyond six colors: a new era in flow cytometry.

    Stephen C. De Rosa;Jason M. Brenchley;Mario Roederer

  • Microbiota-Dependent Sequelae of Acute Infection Compromise Tissue-Specific Immunity

    Denise Morais da Fonseca;Denise Morais da Fonseca;Timothy W. Hand;Seong-Ji Han;Michael Y. Gerner

  • White Adipose Tissue Is a Reservoir for Memory T Cells and Promotes Protective Memory Responses to Infection

    Seong-Ji Han;Arielle Glatman Zaretsky;Vinicius Andrade-Oliveira;Nicholas Collins

  • Toward an AIDS vaccine: lessons from natural simian immunodeficiency virus infections of African nonhuman primate hosts.

    Donald L. Sodora;Jonathan S. Allan;Cristian Apetrei;Cristian Apetrei;Jason M. Brenchley

Frequent Co-Authors

Daniel C. Douek
Daniel C. Douek National Institute of Allergy and Infectious Diseases
Guido Silvestri
Guido Silvestri Emory University
David Price
David Price University of Aberdeen
Jacob D. Estes
Jacob D. Estes Oregon Health & Science University
Vanessa M. Hirsch
Vanessa M. Hirsch National Institute of Allergy and Infectious Diseases
Mirko Paiardini
Mirko Paiardini Emory University
Richard A. Koup
Richard A. Koup National Institute of Allergy and Infectious Diseases
Cristian Apetrei
Cristian Apetrei University of Pittsburgh
Mario Roederer
Mario Roederer National Institute of Allergy and Infectious Diseases
Ivona Pandrea
Ivona Pandrea University of Pittsburgh

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