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Immunology

D-Index
78
Citations
21063
World Ranking
1758
National Ranking
867

Medicine

D-Index
78
Citations
21063
World Ranking
18089
National Ranking
9018

Overview

Vanessa M. Hirsch is affiliated with the National Institute of Allergy and Infectious Diseases in the United States. Their research spans multiple fields within medicine, with a particular focus on immunology and microbiology. Their work covers subfields including epidemiology, infectious diseases, virology, immunology, and cell biology.

The scientist's main topics of investigation include:

  • HIV Research and Treatment
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Tuberculosis Research and Epidemiology
  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • HIV/AIDS drug development and treatment
  • Virology and Viral Diseases

Vanessa M. Hirsch has frequently published in several scientific venues:

  • Viruses
  • mBio
  • The Journal of Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Zenodo (CERN European Organization for Nuclear Research)

Recent papers authored or coauthored by Vanessa M. Hirsch include:

  • "Genomic insights into the host specific adaptation of the Pneumocystis genus," 2021, Communications Biology
  • "Budding of a Retrovirus: Some Assemblies Required," 2020, Viruses
  • "CD4 receptor diversity represents an ancient protection mechanism against primate lentiviruses," 2021, Proceedings of the National Academy of Sciences
  • "Diversity and Complexity of the Large Surface Protein Family in the Compacted Genomes of Multiple Pneumocystis Species," 2020, mBio
  • "When in Need of an ESCRT: The Nature of Virus Assembly Sites Suggests Mechanistic Parallels between Nuclear Virus Egress and Retroviral Budding," 2021, Viruses

Collaborations have been established with several frequent coauthors throughout their career. These include:

  • Jason M. Brenchley
  • Ousmane H. Cissé
  • Bapi Pahar
  • Magali Chabé
  • Rebekah I. Keesler

Best Publications

  • An African primate lentivirus (SIVsm) closely related to HIV-2

    Vanessa M. Hirsch;Robert A. Olmsted;Michael Murphey-Corb;Robert H. Purcell

  • Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections

    Jacob D. Estes;Levelle D. Harris;Nichole R. Klatt;Brian Tabb

  • Vaccine protection against acquisition of neutralization-resistant SIV challenges in rhesus monkeys

    Dan H. Barouch;Dan H. Barouch;Jinyan Liu;Hualin Li;Lori F. Maxfield

  • B cell follicle sanctuary permits persistent productive simian immunodeficiency virus infection in elite controllers.

    Yoshinori Fukazawa;Richard Lum;Afam A Okoye;Haesun Park

  • Macrophage are the principal reservoir and sustain high virus loads in rhesus macaques after the depletion of CD4+ T cells by a highly pathogenic simian immunodeficiency virus/HIV type 1 chimera (SHIV): Implications for HIV-1 infections of humans

    Tatsuhiko Igarashi;Charles R. Brown;Yasuyuki Endo;Alicia Buckler-White

  • Patterns of viral replication correlate with outcome in simian immunodeficiency virus (SIV)-infected macaques: effect of prior immunization with a trivalent SIV vaccine in modified vaccinia virus Ankara.

    V M Hirsch;T R Fuerst;G Sutter;M W Carroll

  • Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth.

    Jinghe Huang;Byong H. Kang;Elise Ishida;Tongqing Zhou

  • Nucleotide sequence analysis of feline immunodeficiency virus: genome organization and relationship to other lentiviruses

    Robert A. Olmsted;Vanessa M. Hirsch;Robert H. Purcell;Philip R. Johnson

  • ALVAC-SIV-gag-pol-env-Based Vaccination and Macaque Major Histocompatibility Complex Class I (A*01) Delay Simian Immunodeficiency Virus SIVmac-Induced Immunodeficiency

    R. Pal;D. Venzon;N. L. Letvin;S. Santra

  • Viral dynamics of primary viremia and antiretroviral therapy in simian immunodeficiency virus infection.

    Martin A. Nowak;Alun L. Lloyd;Gabriela M. Vasquez;Theresa A. Wiltrout

  • CD4-independent, CCR5-dependent infection of brain capillary endothelial cells by a neurovirulent simian immunodeficiency virus strain

    Aimee L. Edinger;Joseph L. Mankowski;Benjamin J. Doranz;Barry J. Margulies

  • Plasma SIV RNA Viral Load Determination by Real-Time Quantification of Product Generation in Reverse Transcriptase-Polymerase Chain Reaction

    Kalachar Suryanarayana;Theresa A. Wiltrout;Gabriela M. Vasquez;Vanessa M. Hirsch

  • Role of CD8+ Lymphocytes in Control of Simian Immunodeficiency Virus Infection and Resistance to Rechallenge after Transient Early Antiretroviral Treatment

    Jeffrey D. Lifson;Jeffrey L. Rossio;Michael Piatak;Thomas Parks

  • Downregulation of Robust Acute Type I Interferon Responses Distinguishes Nonpathogenic Simian Immunodeficiency Virus (SIV) Infection of Natural Hosts from Pathogenic SIV Infection of Rhesus Macaques

    Levelle D. Harris;Brian Tabb;Donald L. Sodora;Mirko Paiardini

  • Induction of AIDS by simian immunodeficiency virus from an African green monkey: species-specific variation in pathogenicity correlates with the extent of in vivo replication.

    Vanessa M. Hirsch;George Dapolito;Philip R. Johnson;William R. Elkins

  • The Extent of Early Viral Replication Is a Critical Determinant of the Natural History of Simian Immunodeficiency Virus Infection

    Jeffrey D. Lifson;Martin A. Nowak;Simoy Goldstein;Jeffrey L. Rossio

  • Reduction of simian-human immunodeficiency virus 89.6P viremia in rhesus monkeys by recombinant modified vaccinia virus Ankara vaccination.

    Dan H. Barouch;Sampa Santra;Marcelo J. Kuroda;Jörn E. Schmitz

  • Molecular cloning of feline immunodeficiency virus.

    Robert A. Olmsted;Andrea K. Barnes;Janet K. Yamamoto;Vanessa M. Hirsch

  • Species-specific diversity among simian immunodeficiency viruses from African green monkeys.

    J. S. Allan;M. Short;M. E. Taylor;Shiawhwa Su

  • TRIM5 suppresses cross-species transmission of a primate immunodeficiency virus and selects for emergence of resistant variants in the new species.

    Andrea Kirmaier;Fan Wu;Ruchi M. Newman;Laura R. Hall

  • Comparative Efficacy of Recombinant Modified Vaccinia Virus Ankara Expressing Simian Immunodeficiency Virus (SIV) Gag-Pol and/or Env in Macaques Challenged with Pathogenic SIV

    Ilnour Ourmanov;Charles R. Brown;Bernard Moss;Miles Carroll

  • Toward an AIDS vaccine: lessons from natural simian immunodeficiency virus infections of African nonhuman primate hosts.

    Donald L. Sodora;Jonathan S. Allan;Cristian Apetrei;Cristian Apetrei;Jason M. Brenchley

  • Loss of mucosal CD103+ DCs and IL-17+ and IL-22+ lymphocytes is associated with mucosal damage in SIV infection.

    Nichole R. Klatt;Jacob D. Estes;Xiaoyong Sun;Alexandra M. Ortiz;Alexandra M. Ortiz

  • Mosaic genome structure of simian immunodeficiency virus from West African green monkeys

    Mojun J. Jin;Huxiong Hui;David L. Robertson;Michaela C. Müller

  • Cloning of HTLV-4 and its relation to simian and human immunodeficiency viruses

    Hardy Kornfeld;Norbert Riedel;Gregory A. Viglianti;Vanessa Hirsch

Frequent Co-Authors

Philip R. Johnson
Philip R. Johnson Children's Hospital of Philadelphia
Alicia Buckler-White
Alicia Buckler-White National Institutes of Health
Jason M. Brenchley
Jason M. Brenchley National Institute of Allergy and Infectious Diseases
David C. Montefiori
David C. Montefiori Duke University
Norman L. Letvin
Norman L. Letvin Beth Israel Deaconess Medical Center
Guido Silvestri
Guido Silvestri Emory University
Cristian Apetrei
Cristian Apetrei University of Pittsburgh
Nancy L. Haigwood
Nancy L. Haigwood Oregon Health & Science University
Jörn E. Schmitz
Jörn E. Schmitz Harvard Medical School
Bernard Moss
Bernard Moss National Institutes of Health

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