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Molecular Biology

D-Index
103
Citations
29251
World Ranking
482
National Ranking
36

Medicine

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104
Citations
30416
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7134
National Ranking
697

Overview

Nicholas R. Lemoine is affiliated with Queen Mary University of London in the United Kingdom. Their research primarily spans the fields of biochemistry, genetics, molecular biology, and medicine, with particular focus on oncology, genetics, immunology, molecular biology, and biotechnology.

Their work concentrates on major topics including CAR-T cell therapy research, virus-based gene therapy research, cancer research and treatments, immunotherapy and immune responses, cancer immunotherapy and biomarkers, immune cell function and interaction, and RNA and protein synthesis mechanisms.

Publications by Nicholas R. Lemoine have appeared frequently in several scientific journals. Notable publication venues include:

  • Frontiers in Immunology (7 publications)
  • Journal for ImmunoTherapy of Cancer (4 publications)
  • Molecular Therapy - Oncolytics (3 publications)
  • Pancreatology (3 publications)
  • Clinical Cancer Research (2 publications)

Some recent papers authored by or involving Lemoine include:

  • SNPnexus: a web server for functional annotation of human genome sequence variation (2020), Nucleic Acids Research
  • CEACAM7 Is an Effective Target for CAR T-cell Therapy of Pancreatic Ductal Adenocarcinoma (2021), Clinical Cancer Research
  • A new oncolytic V accinia virus augments antitumor immune responses to prevent tumor recurrence and metastasis after surgery (2020), Journal for ImmunoTherapy of Cancer
  • Transient Inhibition of PI3Kδ Enhances the Therapeutic Effect of Intravenous Delivery of Oncolytic Vaccinia Virus (2020), Molecular Therapy
  • Oncolytic vaccinia virus and cancer immunotherapy (2024), Frontiers in Immunology

Lemoine has collaborated extensively with several co-authors, including:

  • Yaohe Wang (29 co-authored works)
  • Louisa S. Chard (20 co-authored works)
  • Zhongxian Zhang (10 co-authored works)
  • Shuangshuang Lu (10 co-authored works)
  • Zhenguo Cheng (9 co-authored works)

In addition to articles, Lemoine has contributed to book publications, including the title "Gene Therapy" (2020) published by Garland Science eBooks.

Best Publications

  • Low molecular weight heparin, therapy with dalteparin, and survival in advanced cancer: the fragmin advanced malignancy outcome study (FAMOUS).

    Ajay K. Kakkar;Mark N. Levine;Zbigniew Kadziola;Nicholas R. Lemoine

  • The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a Reaper-like motif

    L. Miguel Martins;Ingram Iaccarino;Tencho Tenev;Stephen Gschmeissner

  • The type 1 (EGFR-related) family of growth factor receptors and their ligands.

    Sally A. Prigent;Nicholas R. Lemoine

  • High frequency of ras oncogene activation in all stages of human thyroid tumorigenesis.

    N R Lemoine;E S Mayall;F S Wyllie;E D Williams

  • Genetic profile of 22 pancreatic carcinoma cell lines. Analysis of K-ras, p53, p16 and DPC4/Smad4.

    Patrick S. Moore;Bence Sipos;Simonetta Orlandini;Claudio Sorio

  • Arginine deprivation and argininosuccinate synthetase expression in the treatment of cancer.

    Barbara Delage;Dean A. Fennell;Linda Nicholson;Iain McNeish;Iain McNeish

  • The ubiquitin-proteasome pathway regulates survivin degradation in a cell cycle-dependent manner

    Jian Zhao;Tencho Tenev;Luis M. Martins;Julian Downward

  • Identification of Novel Isoforms of the BH3 Domain Protein Bim Which Directly Activate Bax To Trigger Apoptosis

    Michela Marani;Tencho Tenev;David Hancock;Julian Downward

  • Yes-associated protein (YAP) functions as a tumor suppressor in breast.

    M Yuan;V Tomlinson;R Lara;D Holliday

  • Expression of the Met/Hepatocyte Growth Factor Receptor in Human Pancreatic Cancer

    M. F. Di Renzo;R. Poulsom;M. Olivero;P. M. Comoglio

  • Cancer gene therapy: hard lessons and new courses.

    R G Vile;S J Russell;N R Lemoine

  • Periostin promotes invasiveness and resistance of pancreatic cancer cells to hypoxia-induced cell death: role of the beta4 integrin and the PI3k pathway.

    P Baril;R Gangeswaran;P C Mahon;K Caulee

  • The use of DNA viruses as vectors for gene therapy.

    M. Ali;N. R. Lemoine;Christopher J. Ring

  • Activated ras oncogenes in human thyroid cancers.

    Lemoine Nr;Mayall Es;Wyllie Fs;Farr Cj

  • Loss of membranous E-cadherin expression in pancreatic cancer: correlation with lymph node metastasis, high grade, and advanced stage.

    Massimo Pignatelli;Tareq W. Ansari;Pat Gunter;Dan Liu

  • Proliferative index in breast carcinoma determined in situ by Ki67 immunostaining and its relationship to clinical and pathological variables

    Nicola J. Barnard;P. A. Hall;N. R. Lemoine;N. Kadar

  • Transforming growth factor alpha and epidermal growth factor in human pancreatic cancer.

    Claire M. Barton;Peter A. Hall;Peter A. Hall;Christine M. Hughes;William J. Gullick

  • Characterization of Gene Expression Profiles in Intraductal Papillary-Mucinous Tumors of the Pancreas

    Benoit Terris;Ekaterina Blaveri;Tatjana Crnogorac-Jurcevic;Melanie Jones

  • Pancreatic cancer: molecular pathogenesis and new therapeutic targets

    Han H. Wong;Nicholas R. Lemoine

  • Pancreatic tumours: molecular pathways implicated in ductal cancer are involved in ampullary but not in exocrine nonductal or endocrine tumorigenesis.

    P Moore;S Orlandini;Giorgio Zamboni;P Capelli

Frequent Co-Authors

Iain A. McNeish
Iain A. McNeish Imperial College London
John P. Neoptolemos
John P. Neoptolemos Heidelberg University
William J. Gullick
William J. Gullick University of Kent
Aldo Scarpa
Aldo Scarpa University of Verona
David Kirn
David Kirn University of California, Berkeley
Massimo Falconi
Massimo Falconi Vita-Salute San Raffaele University
Claudio Bassi
Claudio Bassi University of Verona
Giuseppe Zamboni
Giuseppe Zamboni University of Verona
Thomas M. Gress
Thomas M. Gress Philipp University of Marburg
Julian Downward
Julian Downward The Francis Crick Institute

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