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Medicine

D-Index
109
Citations
41354
World Ranking
5813
National Ranking
326

Overview

Jörg Kleeff is affiliated with Martin Luther University Halle-Wittenberg in Germany. Their research primarily spans the field of Medicine, with significant contributions in Oncology and Surgery as key subfields. Other subfields of study include Pulmonary and Respiratory Medicine, Molecular Biology, and Cancer Research.

Their work covers multiple specialized topics within oncology and gastroenterology. These topics include:

  • Pancreatic and Hepatic Oncology Research
  • Pancreatitis Pathology and Treatment
  • Gastric Cancer Management and Outcomes
  • Renal Cell Carcinoma Treatment
  • Cancer Genomics and Diagnostics
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Esophageal and GI Pathology

Kleeff has been a prolific contributor to a variety of academic journals, frequently publishing in:

  • Pancreatology (22 publications)
  • HPB (17 publications)
  • Cancers (9 publications)
  • Zeitschrift für Gastroenterologie (8 publications)
  • JMIR Research Protocols (6 publications)

Recent papers by Jörg Kleeff include:

  • "Evaluation of Adjuvant Chemotherapy in Patients With Resected Pancreatic Cancer After Neoadjuvant FOLFIRINOX Treatment" (2020) - JAMA Oncology
  • "Adoptive cellular immunotherapy for solid neoplasms beyond CAR-T" (2023) - Molecular Cancer
  • "Identification of prognostic lipid droplet-associated genes in pancreatic cancer patients via bioinformatics analysis" (2021) - Lipids in Health and Disease
  • "Deciphering the complex interplay between pancreatic cancer, diabetes mellitus subtypes and obesity/BMI through causal inference and mediation analyses" (2020) - Gut
  • "Pancreatic Cancer Risk in Relation to Lifetime Smoking Patterns, Tobacco Type, and Dose-Response Relationships" (2020) - Cancer Epidemiology Biomarkers & Prevention

The scientist has collaborated extensively, with frequent co-authors including:

  • Ulrich Ronellenfitsch
  • Artur Rebelo
  • Johannes Klose
  • Yoshiaki Sunami
  • Christoph Michalski

Kleeff has also contributed to book publications, such as "Clinical Trials, Practice and Design in Gastrointestinal Cancers," published by Frontiers Media in 2023.

Best Publications

  • Preoperative/Neoadjuvant Therapy in Pancreatic Cancer: A Systematic Review and Meta-analysis of Response and Resection Percentages

    Sonja Gillen;Tibor Schuster;Christian Meyer zum Büschenfelde;Helmut Friess

  • Therapeutic developments in pancreatic cancer: current and future perspectives.

    John P. Neoptolemos;Jörg Kleeff;Jörg Kleeff;Patrick Michl;Eithne Costello

  • Most pancreatic cancer resections are R1 resections.

    Irene Esposito;Irene Esposito;Jörg Kleeff;Jörg Kleeff;Frank Bergmann;Caroline Reiser;Caroline Reiser

  • Systematic review and meta-analysis of the role of defunctioning stoma in low rectal cancer surgery.

    Norbert Hüser;Christoph W. Michalski;Mert Erkan;Tibor Schuster

  • The role of stroma in pancreatic cancer: diagnostic and therapeutic implications

    Mert Erkan;Simone Hausmann;Christoph W. Michalski;Alexander A. Fingerle

  • Efficacy of stapler versus hand-sewn closure after distal pancreatectomy (DISPACT): a randomised, controlled multicentre trial.

    Markus K. Diener;Christoph M. Seiler;Inga Rossion;Jörg Kleeff

  • Addressing the challenges of pancreatic cancer: future directions for improving outcomes

    Manuel Hidalgo;Stefano Cascinu;Jörg Kleeff;Roberto Labianca

  • Distal pancreatectomy: risk factors for surgical failure in 302 consecutive cases.

    Jörg Kleeff;Markus K. Diener;Kaspar Z'graggen;Ulf Hinz

  • The Activated Stroma Index Is a Novel and Independent Prognostic Marker in Pancreatic Ductal Adenocarcinoma

    Mert Erkan;Christoph W Michalski;Christoph W Michalski;Simon Rieder;Carolin Reiser-Erkan

  • StellaTUM: current consensus and discussion on pancreatic stellate cell research

    Mert Erkan;Guido Adler;Minoti V. Apte;Max G. Bachem

  • The cell-surface heparan sulfate proteoglycan glypican-1 regulates growth factor action in pancreatic carcinoma cells and is overexpressed in human pancreatic cancer.

    Jörg Kleeff;Toshiyuki Ishiwata;Asli Kumbasar;Asli Kumbasar;Helmut Friess

  • Id-1 and Id-2 are overexpressed in pancreatic cancer and in dysplastic lesions in chronic pancreatitis.

    Haruhisa Maruyama;Jörg Kleeff;Stefan Wildi;Helmut Friess

  • Systematic review and meta‐analysis of standard and extended lymphadenectomy in pancreaticoduodenectomy for pancreatic cancer

    C. W. Michalski;J. Kleeff;M. N. Wente;M. K. Diener;M. K. Diener

  • The TGF-β signaling inhibitor Smad7 enhances tumorigenicity in pancreatic cancer

    J. Kleeff;T. Ishiwata;H. Maruyama;H. Friess

  • Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma

    Pawel K Mazur;Alexander Herner;Stephano S Mello;Matthias Wirth

  • Periostin creates a tumor-supportive microenvironment in the pancreas by sustaining fibrogenic stellate cell activity.

    Mert Erkan;Jörg Kleeff;Andre Gorbachevski;Carolin Reiser

  • Heparanase Expression in Primary and Metastatic Pancreatic Cancer

    Alexander Koliopanos;Helmut Friess;Jörg Kleeff;Xin Shi

  • Pancreatogastrostomy Versus Pancreatojejunostomy for RECOnstruction After PANCreatoduodenectomy (RECOPANC, DRKS 00000767) Perioperative and Long-term Results of a Multicenter Randomized Controlled Trial

    Tobias Keck;U. F. Wellner;M. Bahra;F. Klein

  • Transcriptional Network Governing the Angiogenic Switch in Human Pancreatic Cancer

    A. Abdollahi;C. Schwager;J. Kleeff;I. Esposito

  • Cancer-stellate cell interactions perpetuate the hypoxia-fibrosis cycle in pancreatic ductal adenocarcinoma.

    Mert Erkan;Carolin Reiser-Erkan;Christoph W. Michalski;Stefanie Deucker

Frequent Co-Authors

Markus W. Büchler
Markus W. Büchler Champalimaud Foundation
Irene Esposito
Irene Esposito Heinrich Heine University Düsseldorf
Murray Korc
Murray Korc University of California, Irvine
Arthur Zimmermann
Arthur Zimmermann University of Bern
Thomas Giese
Thomas Giese Heidelberg University
John P. Neoptolemos
John P. Neoptolemos Heidelberg University
Julia Mayerle
Julia Mayerle Ludwig-Maximilians-Universität München
Thomas M. Gress
Thomas M. Gress Philipp University of Marburg
Ulf Hinz
Ulf Hinz Heidelberg University
Jens T. Siveke
Jens T. Siveke German Cancer Research Center

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