World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
68
Citations
13055
World Ranking
7969
National Ranking
3608

Research.com Recognitions

  • 2011 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Patrick J. Sinko is affiliated with Rutgers, The State University of New Jersey in the United States. Their research primarily lies within the field of medicine, with a focus on pharmaceutical science, biomaterials, immunology, plant science, and molecular medicine.

The scientist's work encompasses several key topics, including:

  • Nanoparticle-Based Drug Delivery
  • Advanced Drug Delivery Systems
  • Pesticide Exposure and Toxicity
  • Wound Healing and Treatments
  • Curcumin's Biomedical Applications
  • Advancements in Transdermal Drug Delivery
  • Immune cells in cancer

Frequent co-authors collaborating with Patrick J. Sinko include:

  • Jeffrey D. Laskin
  • Dayuan Gao
  • Zoltán Székely
  • Jennifer Holloway
  • Robert K. Prud'homme

Sinko has contributed to publications in notable journals such as Pharmaceutics, Experimental and Molecular Pathology, Antioxidants, Molecular Pharmaceutics, and Journal of Controlled Release.

Selected recent papers by Sinko include:

  • Systematic Development and Characterization of Novel, High Drug-Loaded, Photostable, Curcumin Solid Lipid Nanoparticle Hydrogel for Wound Healing (2021) - Antioxidants
  • A Novel Bivalent Mannosylated Targeting Ligand Displayed on Nanoparticles Selectively Targets Anti-Inflammatory M2 Macrophages (2020) - Pharmaceutics
  • Breast intraductal nanoformulations for treating ductal carcinoma in situ I: Exploring metal-ion complexation to slow ciclopirox release, enhance mammary persistence and efficacy (2020) - Journal of Controlled Release
  • Encapsulation and Controlled Release of a Camptothecin Prodrug from Nanocarriers and Microgels: Tuning Release Rate with Nanocarrier Excipient Composition (2021) - Molecular Pharmaceutics
  • Breast intraductal nanoformulations for treating ductal carcinoma in situ II: Dose de-escalation using a slow releasing/slow bioconverting prodrug strategy (2021) - Drug Delivery and Translational Research

Sinko's research addresses drug delivery innovations, with particular interest in nanoparticle and nanoformulation systems designed for targeted and controlled release of therapeutics in various medical contexts, including cancer treatment and wound healing.

The scientist has been recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2011.

Best Publications

  • Tumor-specific targeting of an anticancer drug delivery system by LHRH peptide

    S. S. Dharap;Y. Wang;P. Chandna;J. J. Khandare

  • Estimating Human Oral Fraction Dose Absorbed: A Correlation Using Rat Intestinal Membrane Permeability for Passive and Carrier-Mediated Compounds

    Gordon L. Amidon;Patrick J. Sinko;David Fleisher

  • Recent trends in targeted anticancer prodrug and conjugate design.

    Yashveer Singh;Matthew Palombo;Patrick J. Sinko

  • The effect of physical barriers and properties on the oral absorption of particulates.

    Daniel A Norris;Navneet Puri;Patrick J Sinko

  • Direct evidence for peptide transporter (PepT1)-mediated uptake of a nonpeptide prodrug, valacyclovir.

    Praveen V. Balimane;Ikumi Tamai;Ailan Guo;Takeo Nakanishi

  • Characterization of the regional intestinal kinetics of drug efflux in rat and human intestine and in Caco-2 cells.

    Vijaya D. Makhey;Ailan Guo;Daniel A. Norris;Peidi Hu

  • Molecular targeting of drug delivery systems to ovarian cancer by BH3 and LHRH peptides.

    S S Dharap;B Qiu;G C Williams;P Sinko

  • Mechanisms Mediating the Vesicant Actions of Sulfur Mustard after Cutaneous Exposure

    Michael P. Shakarjian;Diane E. Heck;Joshua P. Gray;Patrick J. Sinko

  • Effect of size, surface charge, and hydrophobicity on the translocation of polystyrene microspheres through gastrointestinal mucin

    Daniel A. Norris;Patrick J. Sinko

  • Predicting Fraction Dose Absorbed in Humans Using a Macroscopic Mass Balance Approach

    Patrick J. Sinko;Glen D. Leesman;Gordon L. Amidon

  • Involvement of multidrug resistance-associated proteins in regulating cellular levels of (−)-epigallocatechin-3-gallate and its methyl metabolites ☆ ☆☆

    Jungil Hong;Joshua D. Lambert;Sung Hack Lee;Patrick J. Sinko

  • Physiologically-based pharmacokinetic simulation modelling

    George M Grass;Patrick J Sinko

  • Intestinal drug transporters: in vivo function and clinical importance.

    Jeevan R Kunta;Patrick J Sinko

  • Oral absorption of the HIV protease inhibitors: a current update.

    Gregory C. Williams;Patrick J. Sinko

  • A hydrogel prepared by in situ cross-linking of a thiol-containing poly(ethylene glycol)-based copolymer: a new biomaterial for protein drug delivery.

    Bo Qiu;Simon Stefanos;Jianglin Ma;Jianglin Ma;Anita Lalloo

  • Evidence for Diminished Functional Expression of Intestinal Transporters in Caco-2 Cell Monolayers at High Passages

    Hongshi Yu;Thomas J. Cook;Patrick J. Sinko

  • Surface modifications of nanocarriers for effective intracellular delivery of anti-HIV drugs.

    Simi Gunaseelan;Krishnan Gunaseelan;Manjeet Deshmukh;Xiaoping Zhang

  • Interactions of a Nonpeptidic Drug, Valacyclovir, with the Human Intestinal Peptide Transporter (hPEPT1) Expressed in a Mammalian Cell Line

    Ailan Guo;Peidi Hu;Praveen V. Balimane;Frederick H. Leibach

  • Martin's physical pharmacy and pharmaceutical sciences : physical chemical and biopharmaceutical principles in the pharmaceutical sciences

    Alfred N. Martin;Patrick J. Sinko;Yashveer Singh

  • Martin's Physical Pharmacy and Pharmaceutical Sciences/

    Patrick J. Sinko.

Frequent Co-Authors

Stanley Stein
Stanley Stein Rutgers, The State University of New Jersey
Debra L. Laskin
Debra L. Laskin Rutgers, The State University of New Jersey
Jeffrey D. Laskin
Jeffrey D. Laskin Rutgers, The State University of New Jersey
Robert K. Prud'homme
Robert K. Prud'homme Princeton University
Gordon L. Amidon
Gordon L. Amidon University of Michigan–Ann Arbor
Michael L. Chikindas
Michael L. Chikindas Rutgers, The State University of New Jersey
Arnold B. Rabson
Arnold B. Rabson Rutgers, The State University of New Jersey
John E. Anthony
John E. Anthony University of Kentucky
Howard A. Stone
Howard A. Stone Princeton University
Eric J. Rubin
Eric J. Rubin Harvard University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Patrick J. Sinko

Trending Scientists

Recently Published Articles