Ikumi Tamai

Overview

Best Publications

• Molecular and functional identification of sodium ion-dependent, high affinity human carnitine transporter OCTN2.

  Ikumi Tamai;Rikiya Ohashi;Jun-ichi Nezu;Hikaru Yabuuchi

  1016
  Citations

• Molecular identification and characterization of novel members of the human organic anion transporter (OATP) family.

  Ikumi Tamai;Jun-ichi Nezu;Hiroshi Uchino;Yoshimichi Sai

  939
  Citations

• Cloning and characterization of a novel human pH-dependent organic cation transporter, OCTN1

  Ikumi Tamai;Hikaru Yabuuchi;Jun Ichi Nezu;Yoshimichi Sai

  660
  Citations

• Primary systemic carnitine deficiency is caused by mutations in a gene encoding sodium ion-dependent carnitine transporter

  Jun-ichi Nezu;Ikumi Tamai;Asuka Oku;Rikiya Ohashi

  636
  Citations

• Involvement of human organic anion transporting polypeptide OATP-B (SLC21A9) in pH-dependent transport across intestinal apical membrane

  Daisuke Kobayashi;Takashi Nozawa;Kozue Imai;Jun Ichi Nezu

  588
  Citations

• Transporter-mediated permeation of drugs across the blood-brain barrier

  Ikumi Tamai;Akira Tsuji

  520
  Citations

• Functional Characterization of pH-Sensitive Organic Anion Transporting Polypeptide OATP-B in Human

  Takashi Nozawa;Kozue Imai;Jun Ichi Nezu;Akira Tsuji

  493
  Citations

• Genetic polymorphisms of human organic anion transporters OATP-C (SLC21A6) and OATP-B (SLC21A9): allele frequencies in the Japanese population and functional analysis.

  Takashi Nozawa;Miki Nakajima;Ikumi Tamai;Kumiko Noda

  458
  Citations

• Novel membrane transporter OCTN1 mediates multispecific, bidirectional, and pH-dependent transport of organic cations.

  Hikaru Yabuuchi;Ikumi Tamai;Jun-Ichi Nezu;Kazuki Sakamoto

  446
  Citations

• Role of organic anion transporter OATP1B1 (OATP-C) in hepatic uptake of irinotecan and its active metabolite, 7-ethyl-10-hydroxycamptothecin : in vitro evidence and effect of single nucleotide polymorphisms

  Takashi Nozawa;Hironobu Minami;Shigeki Sugiura;Akira Tsuji

  433
  Citations

• Molecular and functional characterization of organic cation/carnitine transporter family in mice.

  Ikumi Tamai;Rikiya Ohashi;Jun-ichi Nezu;Yoshimichi Sai

  426
  Citations

• Identification of MRP2 as a targetable factor limiting oxaliplatin accumulation and response in gastrointestinal cancer.

  Khine Myint;Riya Biswas;Yan Li;Nancy Jong

  403
  Citations

• SGLT2 inhibitor lowers serum uric acid through alteration of uric acid transport activity in renal tubule by increased glycosuria

  Yukihiro Chino;Yukihiro Chino;Yoshishige Samukawa;Soichi Sakai;Yasuhiro Nakai

  393
  Citations

• P-glycoprotein as the drug efflux pump in primary cultured bovine brain capillary endothelial cells.

  Akira Tsuji;Tetsuya Terasaki;Yasushi Takabatake;Yoshiyuki Tenda

  380
  Citations

• Na(+)-dependent carnitine transport by organic cation transporter (OCTN2): its pharmacological and toxicological relevance.

  Rikiya Ohashi;Ikumi Tamai;Hikaru Yabuuchi;Jun-Ichi Nezu

  374
  Citations

• Active Secretion of Drugs from the Small Intestinal Epithelium in Rats by P-Glycoprotein Functioning as an Absorption Barrier

  Toshimitsu Terao;Etsuko Hisanaga;Yoshimichi Sai;Ikumi Tamai

  325
  Citations

• Functional characterization of human organic anion transporting polypeptide B (OATP-B) in comparison with liver-specific OATP-C.

  Ikumi Tamai;Takashi Nozawa;Minako Koshida;Jun-ichi Nezu

  308
  Citations

• Direct evidence for peptide transporter (PepT1)-mediated uptake of a nonpeptide prodrug, valacyclovir.

  Praveen V. Balimane;Ikumi Tamai;Ailan Guo;Takeo Nakanishi

  299
  Citations

• Cellular and molecular mechanisms of dietary regulation on rat intestinal H+/peptide transporter PepT1☆☆☆★

  Toshiyuki Shiraga;Ken-Ichi Miyamoto;Hiroko Tanaka;Hironori Yamamoto

  271
  Citations

• Function and expression of multidrug resistance-associated protein family in human colon adenocarcinoma cells (Caco-2).

  Tomoko Hirohashi;Hiroshi Suzuki;Xiao-Yan Chu;Ikumi Tamai

  270
  Citations