Richard B. Kim

Overview

Best Publications

• Membrane transporters in drug development.

  Kathleen M. Giacomini;Shiew Mei Huang;Donald J. Tweedie;Leslie Z. Benet

  3316
  Citations

• The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors.

  R. B. Kim;M. F. Fromm;C. Wandel;B. Leake

  1314
  Citations

• Identification of functionally variant MDR1 alleles among European Americans and African Americans

  Richard B. Kim;Richard B. Kim;Brenda F. Leake;Brenda F. Leake;Edna F. Choo;Edna F. Choo;George K. Dresser;George K. Dresser

  1285
  Citations

• Polymorphisms in human MDR1 (P-glycoprotein): recent advances and clinical relevance.

  Catia Marzolini;Catia Marzolini;Erik Paus;Erik Paus;Thierry Buclin;Thierry Buclin;Richard B. Kim;Richard B. Kim

  1233
  Citations

• De novo mutations in histone-modifying genes in congenital heart disease

  Samir Zaidi;Murim Choi;Hiroko Wakimoto;Lijiang Ma

  966
  Citations

• SLC transporters as therapeutic targets: emerging opportunities

  Lawrence Lin;Sook Wah Yee;Richard B. Kim;Kathleen M. Giacomini

  780
  Citations

• Pharmacogenetics of efavirenz and central nervous system side effects: an Adult AIDS Clinical Trials Group study.

  David W Haas;Heather J Ribaudo;Richard B Kim;Camlin Tierney

  778
  Citations

• De novo mutations in congenital heart disease with neurodevelopmental and other congenital anomalies.

  Jason Homsy;Samir Zaidi;Yufeng Shen;James S. Ware;James S. Ware;James S. Ware

  774
  Citations

• Contribution of rare inherited and de novo variants in 2,871 congenital heart disease probands

  Sheng Chih Jin;Jason Homsy;Samir Zaidi;Qiongshi Lu

  756
  Citations

• Genetic determinants of response to warfarin during initial anticoagulation.

  Ute I. Schwarz;Marylyn D. Ritchie;Yuki Bradford;Chun Li

  756
  Citations

• Molecular basis of ethnic differences in drug disposition and response.

  H G Xie;R B Kim;A J Wood;C M Stein

  755
  Citations

• Polymorphisms in OATP-C: identification of multiple allelic variants associated with altered transport activity among European- and African-Americans.

  Rommel G. Tirona;Brenda F. Leake;Gracia Merino;Richard B. Kim

  743
  Citations

• Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine.

  George K. Dresser;George K. Dresser;George K. Dresser;David G. Bailey;David G. Bailey;David G. Bailey;Brenda F. Leake;Brenda F. Leake;Brenda F. Leake;Ute I. Schwarz;Ute I. Schwarz;Ute I. Schwarz

  733
  Citations

• OATP and P-Glycoprotein Transporters Mediate the Cellular Uptake and Excretion of Fexofenadine

  Mirjana Cvetkovic;Brenda Leake;Martin F. Fromm;Grant R. Wilkinson

  729
  Citations

• Drug and Bile Acid Transporters in Rosuvastatin Hepatic Uptake: Function, Expression, and Pharmacogenetics

  Richard H. Ho;Rommel G. Tirona;Brenda F. Leake;Hartmut Glaeser

  661
  Citations

• Interrelationship between substrates and inhibitors of human CYP3A and P-glycoprotein.

  R. B. Kim;C. Wandel;B. Leake;M. Cvetkovic

  615
  Citations

• Transporters and drug therapy: implications for drug disposition and disease.

  Richard H. Ho;Richard B. Kim

  555
  Citations

• The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4.

  Rommel G Tirona;Wooin Lee;Brenda F Leake;Lu-Bin Lan

  546
  Citations

• Inhibition of P-Glycoprotein–Mediated Drug Transport A Unifying Mechanism to Explain the Interaction Between Digoxin and Quinidine

  M F Fromm;R B Kim;C M Stein;G R Wilkinson

  515
  Citations

• Pharmacological Inhibition of P-glycoprotein Transport Enhances the Distribution of HIV-1 Protease Inhibitors into Brain and Testes

  Edna F. Choo;Brenda Leake;Christoph Wandel;Hitoshi Imamura

  501
  Citations