World's Best Scientists 2026 revealed!
Hiroyuki Kusuhara

Hiroyuki Kusuhara

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D-Index & Metrics

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Discipline name D-Index World Ranking Current World Ranking National Ranking Current National Ranking Publications Citations
Medicine 94 10617 9969 302 286 368 25563

Hiroyuki Kusuhara publications per year

The chart shows the history of publications by Hiroyuki Kusuhara between 1989 and 2025, highlighting the no. of papers published in each year and offering an overview of the publication velocity of this scholar. Hiroyuki Kusuhara published across 37 years, from 1989 to 2025, averaging 12.1 papers a year. Output peaked at 31 publications in 2024. 56 of the 446 publications appeared in the last two years.

No. of publications
10 20 30
Bar chart. Horizontal axis: year, 1989 to 2025. Vertical axis: number of publications, 0 to 31. Peak 31 publications in 2024. 1989: 4 publications 1990: 4 publications 1991: 0 publications 1992: 0 publications 1993: 2 publications 1994: 0 publications 1995: 1 publication 1996: 1 publication 1997: 2 publications 1998: 5 publications 1999: 7 publications 2000: 1 publication 2001: 5 publications 2002: 8 publications 2003: 14 publications 2004: 15 publications 2005: 19 publications 2006: 12 publications 2007: 20 publications 2008: 14 publications 2009: 13 publications 2010: 14 publications 2011: 13 publications 2012: 9 publications 2013: 20 publications 2014: 18 publications 2015: 11 publications 2016: 12 publications 2017: 25 publications 2018: 17 publications 2019: 26 publications 2020: 18 publications 2021: 21 publications 2022: 18 publications 2023: 21 publications 2024: 31 publications 2025: 25 publications
1989 2025

446 publications in total across all disciplines

View publications per year as a table
Hiroyuki Kusuhara: publications per year, 1989 to 2025
Year Publications
1989 4
1990 4
1991 0
1992 0
1993 2
1994 0
1995 1
1996 1
1997 2
1998 5
1999 7
2000 1
2001 5
2002 8
2003 14
2004 15
2005 19
2006 12
2007 20
2008 14
2009 13
2010 14
2011 13
2012 9
2013 20
2014 18
2015 11
2016 12
2017 25
2018 17
2019 26
2020 18
2021 21
2022 18
2023 21
2024 31
2025 25
Total 446
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Hiroyuki Kusuhara publications per year - data summary

  • Hiroyuki Kusuhara, a Medicine scholar from University of Tokyo, has 446 publications recorded across 37 years, from 1989 to 2025.
  • The oldest publication on record dates to 1989 and the most recent to 2025.
  • The most productive year is 2024, with 31 publications.
  • The least productive years with any output are 1995, 1996 and 2000, with 1 publication each.
  • 3 of the 37 years in the span carry no publications at all (1991, 1992 and 1994).
  • The rate of publication averages 12.1 papers per year over the whole span, or 13.1 per year counting only the 34 years with at least one publication.
  • The last 5 years on the chart (2021-2025) hold 116 publications, 26% of the career total.
  • Split into equal eras - 1989-2001: 32 publications (2.5 per year); 2002-2014: 189 publications (14.5 per year); 2015-2025: 225 publications (20.5 per year).
  • Comparing the opening and closing eras, the overall trend of publication is rising.

Hiroyuki Kusuhara publication distribution in Medicine in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Medicine in 2026. The highlighted bar marks where Hiroyuki Kusuhara sits on this spectrum.

No. of scientists
200 400 600 800
Bar chart with 86 bars. Horizontal axis: publications, 101–120 to 1,796+. Vertical axis: number of scientists, 0 to 922. Most scientists, 922, have 341–360 publications. The last bar groups every scientist with 1,796 publications or more. The highlighted bar, 361–380 publications, is where this scientist sits. 101–120 publications: 5 scientists 121–140 publications: 26 scientists 141–160 publications: 73 scientists 161–180 publications: 155 scientists 181–200 publications: 230 scientists 201–220 publications: 363 scientists 221–240 publications: 487 scientists 241–260 publications: 545 scientists 261–280 publications: 722 scientists 281–300 publications: 768 scientists 301–320 publications: 834 scientists 321–340 publications: 895 scientists 341–360 publications: 922 scientists 361–380 publications: 838 scientists 381–400 publications: 861 scientists 401–420 publications: 918 scientists 421–440 publications: 806 scientists 441–460 publications: 771 scientists 461–480 publications: 751 scientists 481–500 publications: 713 scientists 501–520 publications: 617 scientists 521–540 publications: 610 scientists 541–560 publications: 537 scientists 561–580 publications: 504 scientists 581–600 publications: 509 scientists 601–620 publications: 396 scientists 621–640 publications: 386 scientists 641–660 publications: 371 scientists 661–680 publications: 340 scientists 681–700 publications: 336 scientists 701–720 publications: 307 scientists 721–740 publications: 259 scientists 741–760 publications: 230 scientists 761–780 publications: 228 scientists 781–800 publications: 217 scientists 801–820 publications: 204 scientists 821–840 publications: 186 scientists 841–860 publications: 177 scientists 861–880 publications: 155 scientists 881–900 publications: 139 scientists 901–920 publications: 145 scientists 921–940 publications: 116 scientists 941–960 publications: 133 scientists 961–980 publications: 91 scientists 981–1,000 publications: 96 scientists 1,001–1,020 publications: 77 scientists 1,021–1,040 publications: 70 scientists 1,041–1,060 publications: 63 scientists 1,061–1,080 publications: 77 scientists 1,081–1,100 publications: 49 scientists 1,101–1,120 publications: 54 scientists 1,121–1,140 publications: 49 scientists 1,141–1,160 publications: 51 scientists 1,161–1,180 publications: 35 scientists 1,181–1,200 publications: 39 scientists 1,201–1,220 publications: 26 scientists 1,221–1,240 publications: 37 scientists 1,241–1,260 publications: 36 scientists 1,261–1,280 publications: 27 scientists 1,281–1,300 publications: 32 scientists 1,301–1,320 publications: 28 scientists 1,321–1,340 publications: 17 scientists 1,341–1,360 publications: 30 scientists 1,361–1,380 publications: 28 scientists 1,381–1,400 publications: 17 scientists 1,401–1,420 publications: 21 scientists 1,421–1,440 publications: 15 scientists 1,441–1,460 publications: 12 scientists 1,461–1,480 publications: 12 scientists 1,481–1,500 publications: 18 scientists 1,501–1,520 publications: 14 scientists 1,521–1,540 publications: 17 scientists 1,541–1,560 publications: 15 scientists 1,561–1,580 publications: 6 scientists 1,581–1,600 publications: 2 scientists 1,601–1,620 publications: 12 scientists 1,621–1,640 publications: 11 scientists 1,641–1,660 publications: 8 scientists 1,661–1,680 publications: 5 scientists 1,681–1,700 publications: 5 scientists 1,701–1,720 publications: 10 scientists 1,721–1,740 publications: 12 scientists 1,741–1,760 publications: 14 scientists 1,761–1,780 publications: 6 scientists 1,781–1,795 publications: 5 scientists 1,796+ publications: 100 scientists
101–120 publications 1,796+

This scientist: 368 publications — 32nd percentile

32% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,796 publications or more.

View publications distribution as a table
Number of Medicine scientists by publication count, Research.com 2026 ranking edition. Based on 20,134 ranked scientists.
Publications Scientists This scientist
101–120 5
121–140 26
141–160 73
161–180 155
181–200 230
201–220 363
221–240 487
241–260 545
261–280 722
281–300 768
301–320 834
321–340 895
341–360 922
361–380 838 368
381–400 861
401–420 918
421–440 806
441–460 771
461–480 751
481–500 713
501–520 617
521–540 610
541–560 537
561–580 504
581–600 509
601–620 396
621–640 386
641–660 371
661–680 340
681–700 336
701–720 307
721–740 259
741–760 230
761–780 228
781–800 217
801–820 204
821–840 186
841–860 177
861–880 155
881–900 139
901–920 145
921–940 116
941–960 133
961–980 91
981–1,000 96
1,001–1,020 77
1,021–1,040 70
1,041–1,060 63
1,061–1,080 77
1,081–1,100 49
1,101–1,120 54
1,121–1,140 49
1,141–1,160 51
1,161–1,180 35
1,181–1,200 39
1,201–1,220 26
1,221–1,240 37
1,241–1,260 36
1,261–1,280 27
1,281–1,300 32
1,301–1,320 28
1,321–1,340 17
1,341–1,360 30
1,361–1,380 28
1,381–1,400 17
1,401–1,420 21
1,421–1,440 15
1,441–1,460 12
1,461–1,480 12
1,481–1,500 18
1,501–1,520 14
1,521–1,540 17
1,541–1,560 15
1,561–1,580 6
1,581–1,600 2
1,601–1,620 12
1,621–1,640 11
1,641–1,660 8
1,661–1,680 5
1,681–1,700 5
1,701–1,720 10
1,721–1,740 12
1,741–1,760 14
1,761–1,780 6
1,781–1,795 5
1,796+ 100
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Hiroyuki Kusuhara publication distribution in Medicine in 2026 - data summary

  • The chart plots the publication count of all 20,134 Medicine scientists ranked by Research.com in 2026, grouped into 86 ranges running from 101–120 to 1,796+ publications.
  • Hiroyuki Kusuhara, a Medicine scholar from University of Tokyo, records 368 publications - the 32nd percentile of the discipline.
  • 32% of ranked Medicine scientists score the same or lower than Hiroyuki Kusuhara, and about 68% score higher.
  • The median of the discipline falls in the 441–460 publications range, and Hiroyuki Kusuhara ranks below the median.
  • The most crowded range is 341–360 publications, holding 922 scientists (5% of the field).
  • 64% of the field sits in the lowest quarter of the value range (up to 521–540 publications), so the distribution is heavily right-skewed and high scores are rare.
  • The final bar has no upper bound: it groups every scientist with 1,796 publications or more, 100 scientists in all (<1% of the field).

Hiroyuki Kusuhara D-index placement in Medicine in 2026

The chart shows the D-index (discipline H-index) distribution of Medicine scientists ranked by Research.com in 2026. The highlighted bar marks where Hiroyuki Kusuhara sits on this spectrum.

No. of scientists
250 500 750 1,000
Bar chart with 75 bars. Horizontal axis: D-Index, 70–71 to 217+. Vertical axis: number of scientists, 0 to 1,027. Most scientists, 1,027, have 82–83 D-Index. The last bar groups every scientist with 217 D-Index or more. The highlighted bar, 94–95 D-Index, is where this scientist sits. 70–71 D-Index: 226 scientists 72–73 D-Index: 391 scientists 74–75 D-Index: 574 scientists 76–77 D-Index: 730 scientists 78–79 D-Index: 891 scientists 80–81 D-Index: 972 scientists 82–83 D-Index: 1,027 scientists 84–85 D-Index: 1,003 scientists 86–87 D-Index: 960 scientists 88–89 D-Index: 970 scientists 90–91 D-Index: 922 scientists 92–93 D-Index: 839 scientists 94–95 D-Index: 808 scientists 96–97 D-Index: 779 scientists 98–99 D-Index: 668 scientists 100–101 D-Index: 611 scientists 102–103 D-Index: 630 scientists 104–105 D-Index: 513 scientists 106–107 D-Index: 541 scientists 108–109 D-Index: 445 scientists 110–111 D-Index: 429 scientists 112–113 D-Index: 399 scientists 114–115 D-Index: 393 scientists 116–117 D-Index: 318 scientists 118–119 D-Index: 302 scientists 120–121 D-Index: 287 scientists 122–123 D-Index: 255 scientists 124–125 D-Index: 256 scientists 126–127 D-Index: 252 scientists 128–129 D-Index: 230 scientists 130–131 D-Index: 179 scientists 132–133 D-Index: 168 scientists 134–135 D-Index: 163 scientists 136–137 D-Index: 159 scientists 138–139 D-Index: 134 scientists 140–141 D-Index: 134 scientists 142–143 D-Index: 118 scientists 144–145 D-Index: 109 scientists 146–147 D-Index: 106 scientists 148–149 D-Index: 74 scientists 150–151 D-Index: 79 scientists 152–153 D-Index: 80 scientists 154–155 D-Index: 87 scientists 156–157 D-Index: 57 scientists 158–159 D-Index: 74 scientists 160–161 D-Index: 69 scientists 162–163 D-Index: 60 scientists 164–165 D-Index: 53 scientists 166–167 D-Index: 39 scientists 168–169 D-Index: 42 scientists 170–171 D-Index: 32 scientists 172–173 D-Index: 39 scientists 174–175 D-Index: 40 scientists 176–177 D-Index: 28 scientists 178–179 D-Index: 19 scientists 180–181 D-Index: 23 scientists 182–183 D-Index: 31 scientists 184–185 D-Index: 18 scientists 186–187 D-Index: 20 scientists 188–189 D-Index: 22 scientists 190–191 D-Index: 13 scientists 192–193 D-Index: 21 scientists 194–195 D-Index: 12 scientists 196–197 D-Index: 12 scientists 198–199 D-Index: 14 scientists 200–201 D-Index: 15 scientists 202–203 D-Index: 13 scientists 204–205 D-Index: 10 scientists 206–207 D-Index: 8 scientists 208–209 D-Index: 4 scientists 210–211 D-Index: 12 scientists 212–213 D-Index: 11 scientists 214–215 D-Index: 10 scientists 216 D-Index: 4 scientists 217+ D-Index: 98 scientists
70–71 D-Index 217+

This scientist: 94 D-Index — 49th percentile

49% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 217 D-Index or more.

View D-Index distribution as a table
Number of Medicine scientists by D-index, Research.com 2026 ranking edition. Based on 20,134 ranked scientists.
D-Index Scientists This scientist
70–71 226
72–73 391
74–75 574
76–77 730
78–79 891
80–81 972
82–83 1,027
84–85 1,003
86–87 960
88–89 970
90–91 922
92–93 839
94–95 808 94
96–97 779
98–99 668
100–101 611
102–103 630
104–105 513
106–107 541
108–109 445
110–111 429
112–113 399
114–115 393
116–117 318
118–119 302
120–121 287
122–123 255
124–125 256
126–127 252
128–129 230
130–131 179
132–133 168
134–135 163
136–137 159
138–139 134
140–141 134
142–143 118
144–145 109
146–147 106
148–149 74
150–151 79
152–153 80
154–155 87
156–157 57
158–159 74
160–161 69
162–163 60
164–165 53
166–167 39
168–169 42
170–171 32
172–173 39
174–175 40
176–177 28
178–179 19
180–181 23
182–183 31
184–185 18
186–187 20
188–189 22
190–191 13
192–193 21
194–195 12
196–197 12
198–199 14
200–201 15
202–203 13
204–205 10
206–207 8
208–209 4
210–211 12
212–213 11
214–215 10
216 4
217+ 98
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Hiroyuki Kusuhara D-index placement in Medicine in 2026 - data summary

  • The chart plots the discipline H-index (D-index) of all 20,134 Medicine scientists ranked by Research.com in 2026, grouped into 75 ranges running from 70–71 to 217+ D-Index.
  • Hiroyuki Kusuhara, a Medicine scholar from University of Tokyo, records 94 D-Index - the 49th percentile of the discipline.
  • 49% of ranked Medicine scientists score the same or lower than Hiroyuki Kusuhara, and about 51% score higher.
  • The median of the discipline falls in the 94–95 D-Index range, and Hiroyuki Kusuhara falls inside that same range.
  • The most crowded range is 82–83 D-Index, holding 1,027 scientists (5% of the field).
  • 70% of the field sits in the lowest quarter of the value range (up to 106–107 D-Index), so the distribution is heavily right-skewed and high scores are rare.
  • The final bar has no upper bound: it groups every scientist with 217 D-Index or more, 98 scientists in all (<1% of the field).

Overview

Hiroyuki Kusuhara is affiliated with the University of Tokyo in Japan and has a significant body of research in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their scholarly work spans multiple subfields including Molecular Biology, Oncology, Pharmacology, Pediatrics, Perinatology and Child Health, as well as Computational Theory and Mathematics.

The primary topics of Kusuhara's research include Drug Transport and Resistance Mechanisms, Pharmacogenetics and Drug Metabolism, Computational Drug Discovery Methods, Pharmacological Effects and Toxicity Studies, Amino Acid Enzymes and Metabolism, Machine Learning in Materials Science, and Metabolomics and Mass Spectrometry Studies.

Kusuhara's recent publications illustrate the scope and diversity of their research interests. The following papers reflect contributions to pharmaceutical sciences, pharmacokinetics, and biomedical engineering:

  • "Phase 0/microdosing approaches: time for mainstream application in drug development?", 2020, Nature Reviews Drug Discovery
  • "Identification of Appropriate Endogenous Biomarker for Risk Assessment of Multidrug and Toxin Extrusion Protein-Mediated Drug-Drug Interactions in Healthy Volunteers", 2020, Clinical Pharmacology & Therapeutics
  • "Usability of Polydimethylsiloxane-Based Microfluidic Devices in Pharmaceutical Research Using Human Hepatocytes", 2021, ACS Biomaterials Science & Engineering
  • "A general fluorescence off/on strategy for fluorogenic probes: Steric repulsion-induced twisted intramolecular charge transfer (sr-TICT)", 2024, Science Advances
  • "Alteration in the Plasma Concentrations of Endogenous Organic Anion-Transporting Polypeptide 1B Biomarkers in Patients with Non-Small Cell Lung Cancer Treated with Paclitaxel", 2020, Drug Metabolism and Disposition

Kusuhara frequently publishes in several scientific venues, including:

  • Drug Metabolism and Disposition
  • Drug Metabolism and Pharmacokinetics
  • bioRxiv (Cold Spring Harbor Laboratory)
  • arXiv (Cornell University)
  • Clinical Pharmacology & Therapeutics

Collaborations are an important aspect of Kusuhara's research environment. The most frequent coauthors include Tadahaya Mizuno, Kazuya Maeda, Yuichi Sugiyama, Katsuhisa Morita, and Shumpei Nemoto, highlighting an active research network across multiple projects.

Best Publications

  • Polymorphisms of OATP-C (SLC21A6) and OAT3 (SLC22A8) genes: consequences for pravastatin pharmacokinetics.

    Yohei Nishizato;Ichiro Ieiri;Hiroshi Suzuki;Miyuki Kimura

  • Molecular Cloning and Characterization of a New Multispecific Organic Anion Transporter from Rat Brain

    Hiroyuki Kusuhara;Takashi Sekine;Naoko Utsunomiya-Tate;Minoru Tsuda

  • Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta.

    Seok Ho Cha;Takashi Sekine;Hiroyuki Kusuhara;Hiroyuki Kusuhara;Erkang Yu

  • Involvement of Organic Cation Transporter 1 in Hepatic and Intestinal Distribution of Metformin

    De-Sheng Wang;Johan W. Jonker;Yukio Kato;Hiroyuki Kusuhara

  • Physiologically Based Pharmacokinetic Modeling to Predict Transporter-Mediated Clearance and Distribution of Pravastatin in Humans

    Takao Watanabe;Hiroyuki Kusuhara;Kazuya Maeda;Yoshihisa Shitara

  • Kinetic Analysis of the Cooperation of P-Glycoprotein (P-gp/Abcb1) and Breast Cancer Resistance Protein (Bcrp/Abcg2) in Limiting the Brain and Testis Penetration of Erlotinib, Flavopiridol, and Mitoxantrone

    Hiroshi Kodaira;Hiroyuki Kusuhara;Junko Ushiki;Eiichi Fuse

  • Functional involvement of multidrug resistance-associated protein 4 (MRP4/ABCC4) in the renal elimination of the antiviral drugs adefovir and tenofovir.

    Tomoki Imaoka;Hiroyuki Kusuhara;Masashi Adachi;John D. Schuetz

  • Functional Characterization of Rat Brain-specific Organic Anion Transporter (Oatp14) at the Blood-Brain Barrier HIGH AFFINITY TRANSPORTER FOR THYROXINE

    Daisuke Sugiyama;Hiroyuki Kusuhara;Hirokazu Taniguchi;Shumpei Ishikawa

  • Cyclosporin A and its analogs inhibit hepatitis B virus entry into cultured hepatocytes through targeting a membrane transporter, sodium taurocholate cotransporting polypeptide (NTCP)

    Koichi Watashi;Ann Sluder;Takuji Daito;Takuji Daito;Satoko Matsunaga

  • Characterization of uremic toxin transport by organic anion transporters in the kidney.

    Tsuneo Deguchi;Hiroyuki Kusuhara;Akira Takadate;Hitoshi Endou

  • Involvement of BCRP (ABCG2) in the Biliary Excretion of Pitavastatin

    Masaru Hirano;Kazuya Maeda;Soichiro Matsushima;Yoshitane Nozaki

  • Active efflux across the blood-brain barrier: role of the solute carrier family.

    Hiroyuki Kusuhara;Yuichi Sugiyama

  • Evaluation and identification of hepatitis B virus entry inhibitors using HepG2 cells overexpressing a membrane transporter NTCP.

    Masashi Iwamoto;Koichi Watashi;Koichi Watashi;Senko Tsukuda;Hussein Hassan Aly

  • In vitro-in vivo extrapolation of transporter-mediated clearance in the liver and kidney.

    Hiroyuki Kusuhara;Yuichi Sugiyama

  • Effect of breast cancer resistance protein (Bcrp/Abcg2) on the disposition of phytoestrogens.

    Junichi Enokizono;Hiroyuki Kusuhara;Yuichi Sugiyama

  • Characterization of the Efflux Transport of 17β-Estradiol-d-17β-glucuronide from the Brain across the Blood-Brain Barrier

    Daisuke Sugiyama;Hiroyuki Kusuhara;Yoshihisa Shitara;Takaaki Abe

  • Competitive Inhibition of the Luminal Efflux by Multidrug and Toxin Extrusions, but Not Basolateral Uptake by Organic Cation Transporter 2, Is the Likely Mechanism Underlying the Pharmacokinetic Drug-Drug Interactions Caused by Cimetidine in the Kidney

    Sumito Ito;Hiroyuki Kusuhara;Miyu Yokochi;Junko Toyoshima

  • Quantitative Evaluation of the Therapeutic Effects of Antibiotics Using Silkworms Infected with Human Pathogenic Microorganisms

    Hiroshi Hamamoto;Kenji Kurokawa;Chikara Kaito;Koushirou Kamura

  • Role of transporters in the tissue-selective distribution and elimination of drugs: transporters in the liver, small intestine, brain and kidney.

    Hiroyuki Kusuhara;Yuichi Sugiyama

  • Functional characterization of rat brain-specific organic anion transporter (Oatp14) at the blood-brain barrier. High affinity transporter for thyroxine. Vol. 278 (2003) 43489-43495

    Daisuke Sugiyama;Hiroyuki Kusuhara;Hirokazu Taniguchi;Shumpei Ishikawa

Frequent Co-Authors

Yuichi Sugiyama
Yuichi Sugiyama University of Tokyo
Hitoshi Endou
Hitoshi Endou Kyorin University
Hiroshi Suzuki
Hiroshi Suzuki Obihiro University of Agriculture and Veterinary Medicine
John D. Schuetz
John D. Schuetz St. Jude Children's Research Hospital
Yasuyoshi Watanabe
Yasuyoshi Watanabe Osaka Metropolitan University
Tetsuya Suhara
Tetsuya Suhara National Institutes for Quantum and Radiological Science and Technology
Yoshinori Moriyama
Yoshinori Moriyama Okayama University
Kozo Takayama
Kozo Takayama Josai University
Hiroshi Ito
Hiroshi Ito Fukushima Medical University
Koichi Watashi
Koichi Watashi National Institute of Infectious Diseases

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