D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 85 Citations 20,397 309 World Ranking 9754 National Ranking 281

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Internal medicine

His primary scientific interests are in Pharmacology, Biochemistry, Organic anion transporter 1, Efflux and Transporter. His Pharmacology research includes elements of Internal medicine, Kidney, Abcg2 and Multidrug resistance-associated protein 2. His Organic Anion Transport Protein 1 and Glucuronide study in the realm of Biochemistry connects with subjects such as Sitosterolemia.

The Organic anion transporter 1 study combines topics in areas such as Probenecid, Virus, Viral replication and Organic cation transport proteins. His work deals with themes such as P-glycoprotein, Blood–brain barrier and Intracellular, which intersect with Efflux. As part of one scientific family, Hiroyuki Kusuhara deals mainly with the area of Transporter, narrowing it down to issues related to the Drug, and often Biophysics and Cerebrospinal fluid.

His most cited work include:

  • Polymorphisms of OATP-C (SLC21A6) and OAT3 (SLC22A8) genes: consequences for pravastatin pharmacokinetics. (471 citations)
  • Molecular Cloning and Characterization of a New Multispecific Organic Anion Transporter from Rat Brain (450 citations)
  • Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta. (362 citations)

What are the main themes of his work throughout his whole career to date?

Hiroyuki Kusuhara mostly deals with Pharmacology, Transporter, Pharmacokinetics, Internal medicine and Organic anion transporter 1. His research in Pharmacology intersects with topics in Efflux, Kidney, Abcg2 and In vivo. His studies deal with areas such as Cell biology and Choroid plexus as well as Transporter.

His work on Physiologically based pharmacokinetic modelling as part of general Pharmacokinetics research is frequently linked to Crossover study, bridging the gap between disciplines. Hiroyuki Kusuhara usually deals with Internal medicine and limits it to topics linked to Endocrinology and Knockout mouse. Organic anion transporter 1 is the subject of his research, which falls under Biochemistry.

He most often published in these fields:

  • Pharmacology (47.96%)
  • Transporter (23.20%)
  • Pharmacokinetics (21.94%)

What were the highlights of his more recent work (between 2017-2021)?

  • Pharmacology (47.96%)
  • Drug (10.03%)
  • Pharmacokinetics (21.94%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Pharmacology, Drug, Pharmacokinetics, Transporter and In vivo. His work on Pitavastatin as part of general Pharmacology research is often related to Crossover study, thus linking different fields of science. His Pharmacokinetics research includes elements of Oral administration, Distribution and Multidrug resistance-associated protein 2.

The concepts of his Transporter study are interwoven with issues in Phenotype, Efflux, In vitro and Cell biology. His Efflux study integrates concerns from other disciplines, such as Abcg2, Ussing chamber, Peptide transporter 1, Molecular biology and Kidney. His In vivo study combines topics in areas such as Biomarker, Local field potential and Premovement neuronal activity.

Between 2017 and 2021, his most popular works were:

  • Clinical Probes and Endogenous Biomarkers as Substrates for Transporter Drug-Drug Interaction Evaluation: Perspectives From the International Transporter Consortium (49 citations)
  • Endogenous Probes for Drug Transporters: Balancing Vision With Reality. (49 citations)
  • Comparative Study of the Dose-Dependence of OATP1B Inhibition by Rifampicin Using Probe Drugs and Endogenous Substrates in Healthy Volunteers. (35 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Internal medicine

Hiroyuki Kusuhara focuses on Pharmacology, Transporter, Pharmacokinetics, Endogeny and In vivo. His Pharmacology research integrates issues from Organic anion transporter 1, Organic anion-transporting polypeptide, Biomarker and Rifampicin. His Organic anion transporter 1 research incorporates elements of Cimetidine and Renal function.

He combines subjects such as Inflammation, Lipopolysaccharide, Drug and Cell biology with his study of Transporter. His Pharmacokinetics study deals with Distribution intersecting with Excretion, Drug development, New chemical entity and Urine. His In vivo research is multidisciplinary, incorporating elements of Messenger RNA, Gene knockin, Sultopride and Ligand.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Polymorphisms of OATP-C (SLC21A6) and OAT3 (SLC22A8) genes: consequences for pravastatin pharmacokinetics.

Yohei Nishizato;Ichiro Ieiri;Hiroshi Suzuki;Miyuki Kimura.
Clinical Pharmacology & Therapeutics (2003)

735 Citations

Molecular Cloning and Characterization of a New Multispecific Organic Anion Transporter from Rat Brain

Hiroyuki Kusuhara;Takashi Sekine;Naoko Utsunomiya-Tate;Minoru Tsuda.
Journal of Biological Chemistry (1999)

711 Citations

Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta.

Seok Ho Cha;Takashi Sekine;Hiroyuki Kusuhara;Hiroyuki Kusuhara;Erkang Yu.
Journal of Biological Chemistry (2000)

570 Citations

Physiologically Based Pharmacokinetic Modeling to Predict Transporter-Mediated Clearance and Distribution of Pravastatin in Humans

Takao Watanabe;Hiroyuki Kusuhara;Kazuya Maeda;Yoshihisa Shitara.
Journal of Pharmacology and Experimental Therapeutics (2009)

366 Citations

Kinetic Analysis of the Cooperation of P-Glycoprotein (P-gp/Abcb1) and Breast Cancer Resistance Protein (Bcrp/Abcg2) in Limiting the Brain and Testis Penetration of Erlotinib, Flavopiridol, and Mitoxantrone

Hiroshi Kodaira;Hiroyuki Kusuhara;Junko Ushiki;Eiichi Fuse.
Journal of Pharmacology and Experimental Therapeutics (2010)

356 Citations

Functional involvement of multidrug resistance-associated protein 4 (MRP4/ABCC4) in the renal elimination of the antiviral drugs adefovir and tenofovir.

Tomoki Imaoka;Hiroyuki Kusuhara;Masashi Adachi;John D. Schuetz.
Molecular Pharmacology (2007)

336 Citations

Functional Characterization of Rat Brain-specific Organic Anion Transporter (Oatp14) at the Blood-Brain Barrier HIGH AFFINITY TRANSPORTER FOR THYROXINE

Daisuke Sugiyama;Hiroyuki Kusuhara;Hirokazu Taniguchi;Shumpei Ishikawa.
Journal of Biological Chemistry (2003)

318 Citations

Involvement of BCRP (ABCG2) in the Biliary Excretion of Pitavastatin

Masaru Hirano;Kazuya Maeda;Soichiro Matsushima;Yoshitane Nozaki.
Molecular Pharmacology (2005)

309 Citations

Active efflux across the blood-brain barrier: role of the solute carrier family.

Hiroyuki Kusuhara;Yuichi Sugiyama.
Neurorx (2005)

309 Citations

Cyclosporin A and its analogs inhibit hepatitis B virus entry into cultured hepatocytes through targeting a membrane transporter, sodium taurocholate cotransporting polypeptide (NTCP)

Koichi Watashi;Ann Sluder;Takuji Daito;Takuji Daito;Satoko Matsunaga.
Hepatology (2014)

286 Citations

If you think any of the details on this page are incorrect, let us know.

Contact us

Best Scientists Citing Hiroyuki Kusuhara

Yuichi Sugiyama

Yuichi Sugiyama

University of Tokyo

Publications: 140

Kazuhisa Sekimizu

Kazuhisa Sekimizu

University of Tokyo

Publications: 80

Hitoshi Endou

Hitoshi Endou

Kyorin University

Publications: 80

Koichi Watashi

Koichi Watashi

National Institute of Infectious Diseases

Publications: 69

Ikumi Tamai

Ikumi Tamai

Kanazawa University

Publications: 67

Tetsuya Terasaki

Tetsuya Terasaki

Tohoku University

Publications: 58

Kathleen M. Giacomini

Kathleen M. Giacomini

University of California, San Francisco

Publications: 54

Jos H. Beijnen

Jos H. Beijnen

Antoni van Leeuwenhoek Hospital

Publications: 53

Ken-ichi Inui

Ken-ichi Inui

Kyoto Pharmaceutical University

Publications: 47

Sumio Ohtsuki

Sumio Ohtsuki

Kumamoto University

Publications: 46

Bruno Stieger

Bruno Stieger

University of Zurich

Publications: 46

Mikko Niemi

Mikko Niemi

University of Helsinki

Publications: 46

Alfred H. Schinkel

Alfred H. Schinkel

Antoni van Leeuwenhoek Hospital

Publications: 44

Richard B. Kim

Richard B. Kim

University of Western Ontario

Publications: 42

Sanjay K. Nigam

Sanjay K. Nigam

University of California, San Diego

Publications: 40

Ken-ichi Hosoya

Ken-ichi Hosoya

University of Toyama

Publications: 40

Trending Scientists

john g webster

john g webster

University of Wisconsin–Madison

Dirk Lefeber

Dirk Lefeber

Vrije Universiteit Brussel

Monika Österberg

Monika Österberg

Aalto University

Richard Needleman

Richard Needleman

Wayne State University

K. Y. Simon Ng

K. Y. Simon Ng

Wayne State University

Renzo Rossi

Renzo Rossi

University of Pisa

Hongkai Wu

Hongkai Wu

Hong Kong University of Science and Technology

Sally A. Camper

Sally A. Camper

University of Michigan–Ann Arbor

A. Rus Hoelzel

A. Rus Hoelzel

Durham University

Dirk Zeller

Dirk Zeller

University of Western Australia

Jeffrey E. Gerst

Jeffrey E. Gerst

Weizmann Institute of Science

Hojeong Kang

Hojeong Kang

Yonsei University

Christoph Beglinger

Christoph Beglinger

University of Basel

Flavia M. Cicuttini

Flavia M. Cicuttini

Monash University

Thomas A. Gennarelli

Thomas A. Gennarelli

University of Pennsylvania

Timothy Earle

Timothy Earle

Northwestern University

Something went wrong. Please try again later.