World's Best Scientists 2026 revealed!
Hiroyuki Kusuhara

Hiroyuki Kusuhara

D-Index & Metrics

Medicine

D-Index
94
Citations
25563
World Ranking
10618
National Ranking
302

Hiroyuki Kusuhara publication distribution in Medicine in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Medicine in 2026. The highlighted bar marks where Hiroyuki Kusuhara sits on this spectrum.

101–120 publications: 5 scientists 121–140 publications: 26 scientists 141–160 publications: 73 scientists 161–180 publications: 155 scientists 181–200 publications: 230 scientists 201–220 publications: 363 scientists 221–240 publications: 487 scientists 241–260 publications: 545 scientists 261–280 publications: 722 scientists 281–300 publications: 768 scientists 301–320 publications: 834 scientists 321–340 publications: 895 scientists 341–360 publications: 922 scientists 361–380 publications: 838 scientists 381–400 publications: 861 scientists 401–420 publications: 918 scientists 421–440 publications: 806 scientists 441–460 publications: 771 scientists 461–480 publications: 751 scientists 481–500 publications: 713 scientists 501–520 publications: 617 scientists 521–540 publications: 611 scientists 541–560 publications: 537 scientists 561–580 publications: 504 scientists 581–600 publications: 509 scientists 601–620 publications: 396 scientists 621–640 publications: 386 scientists 641–660 publications: 371 scientists 661–680 publications: 340 scientists 681–700 publications: 336 scientists 701–720 publications: 307 scientists 721–740 publications: 259 scientists 741–760 publications: 230 scientists 761–780 publications: 228 scientists 781–800 publications: 217 scientists 801–820 publications: 204 scientists 821–840 publications: 186 scientists 841–860 publications: 177 scientists 861–880 publications: 155 scientists 881–900 publications: 139 scientists 901–920 publications: 145 scientists 921–940 publications: 116 scientists 941–960 publications: 133 scientists 961–980 publications: 91 scientists 981–1,000 publications: 96 scientists 1,001–1,020 publications: 77 scientists 1,021–1,040 publications: 70 scientists 1,041–1,060 publications: 63 scientists 1,061–1,080 publications: 77 scientists 1,081–1,100 publications: 49 scientists 1,101–1,120 publications: 54 scientists 1,121–1,140 publications: 49 scientists 1,141–1,160 publications: 51 scientists 1,161–1,180 publications: 35 scientists 1,181–1,200 publications: 39 scientists 1,201–1,220 publications: 26 scientists 1,221–1,240 publications: 37 scientists 1,241–1,260 publications: 36 scientists 1,261–1,280 publications: 27 scientists 1,281–1,300 publications: 32 scientists 1,301–1,320 publications: 28 scientists 1,321–1,340 publications: 17 scientists 1,341–1,360 publications: 30 scientists 1,361–1,380 publications: 28 scientists 1,381–1,400 publications: 17 scientists 1,401–1,420 publications: 21 scientists 1,421–1,440 publications: 15 scientists 1,441–1,460 publications: 12 scientists 1,461–1,480 publications: 12 scientists 1,481–1,500 publications: 18 scientists 1,501–1,520 publications: 14 scientists 1,521–1,540 publications: 17 scientists 1,541–1,560 publications: 15 scientists 1,561–1,580 publications: 6 scientists 1,581–1,600 publications: 2 scientists 1,601–1,620 publications: 12 scientists 1,621–1,640 publications: 11 scientists 1,641–1,660 publications: 8 scientists 1,661–1,680 publications: 5 scientists 1,681–1,700 publications: 5 scientists 1,701–1,720 publications: 10 scientists 1,721–1,740 publications: 12 scientists 1,741–1,760 publications: 14 scientists 1,761–1,780 publications: 6 scientists 1,781–1,795 publications: 5 scientists 1,796+ publications: 100 scientists
101 publications 1,796+

This scientist: 368 publications — 32nd percentile

32% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,796 publications or more.

Hiroyuki Kusuhara D-index placement in Medicine in 2026

The chart shows the D-index (discipline H-index) distribution of Medicine scientists ranked by Research.com in 2026. The highlighted bar marks where Hiroyuki Kusuhara sits on this spectrum.

70–71 D-Index: 226 scientists 72–73 D-Index: 391 scientists 74–75 D-Index: 574 scientists 76–77 D-Index: 730 scientists 78–79 D-Index: 891 scientists 80–81 D-Index: 972 scientists 82–83 D-Index: 1,027 scientists 84–85 D-Index: 1,003 scientists 86–87 D-Index: 960 scientists 88–89 D-Index: 970 scientists 90–91 D-Index: 922 scientists 92–93 D-Index: 839 scientists 94–95 D-Index: 808 scientists 96–97 D-Index: 779 scientists 98–99 D-Index: 668 scientists 100–101 D-Index: 611 scientists 102–103 D-Index: 630 scientists 104–105 D-Index: 513 scientists 106–107 D-Index: 541 scientists 108–109 D-Index: 445 scientists 110–111 D-Index: 429 scientists 112–113 D-Index: 400 scientists 114–115 D-Index: 393 scientists 116–117 D-Index: 318 scientists 118–119 D-Index: 302 scientists 120–121 D-Index: 287 scientists 122–123 D-Index: 255 scientists 124–125 D-Index: 256 scientists 126–127 D-Index: 252 scientists 128–129 D-Index: 230 scientists 130–131 D-Index: 179 scientists 132–133 D-Index: 168 scientists 134–135 D-Index: 163 scientists 136–137 D-Index: 159 scientists 138–139 D-Index: 134 scientists 140–141 D-Index: 134 scientists 142–143 D-Index: 118 scientists 144–145 D-Index: 109 scientists 146–147 D-Index: 106 scientists 148–149 D-Index: 74 scientists 150–151 D-Index: 79 scientists 152–153 D-Index: 80 scientists 154–155 D-Index: 87 scientists 156–157 D-Index: 57 scientists 158–159 D-Index: 74 scientists 160–161 D-Index: 69 scientists 162–163 D-Index: 60 scientists 164–165 D-Index: 53 scientists 166–167 D-Index: 39 scientists 168–169 D-Index: 42 scientists 170–171 D-Index: 32 scientists 172–173 D-Index: 39 scientists 174–175 D-Index: 40 scientists 176–177 D-Index: 28 scientists 178–179 D-Index: 19 scientists 180–181 D-Index: 23 scientists 182–183 D-Index: 31 scientists 184–185 D-Index: 18 scientists 186–187 D-Index: 20 scientists 188–189 D-Index: 22 scientists 190–191 D-Index: 13 scientists 192–193 D-Index: 21 scientists 194–195 D-Index: 12 scientists 196–197 D-Index: 12 scientists 198–199 D-Index: 14 scientists 200–201 D-Index: 15 scientists 202–203 D-Index: 13 scientists 204–205 D-Index: 10 scientists 206–207 D-Index: 8 scientists 208–209 D-Index: 4 scientists 210–211 D-Index: 12 scientists 212–213 D-Index: 11 scientists 214–215 D-Index: 10 scientists 216 D-Index: 4 scientists 217+ D-Index: 98 scientists
70 D-Index 217+

This scientist: 94 D-Index — 49th percentile

49% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 217 D-Index or more.

Overview

Hiroyuki Kusuhara is affiliated with the University of Tokyo in Japan and has a significant body of research in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their scholarly work spans multiple subfields including Molecular Biology, Oncology, Pharmacology, Pediatrics, Perinatology and Child Health, as well as Computational Theory and Mathematics.

The primary topics of Kusuhara's research include Drug Transport and Resistance Mechanisms, Pharmacogenetics and Drug Metabolism, Computational Drug Discovery Methods, Pharmacological Effects and Toxicity Studies, Amino Acid Enzymes and Metabolism, Machine Learning in Materials Science, and Metabolomics and Mass Spectrometry Studies.

Kusuhara's recent publications illustrate the scope and diversity of their research interests. The following papers reflect contributions to pharmaceutical sciences, pharmacokinetics, and biomedical engineering:

  • "Phase 0/microdosing approaches: time for mainstream application in drug development?", 2020, Nature Reviews Drug Discovery
  • "Identification of Appropriate Endogenous Biomarker for Risk Assessment of Multidrug and Toxin Extrusion Protein-Mediated Drug-Drug Interactions in Healthy Volunteers", 2020, Clinical Pharmacology & Therapeutics
  • "Usability of Polydimethylsiloxane-Based Microfluidic Devices in Pharmaceutical Research Using Human Hepatocytes", 2021, ACS Biomaterials Science & Engineering
  • "A general fluorescence off/on strategy for fluorogenic probes: Steric repulsion-induced twisted intramolecular charge transfer (sr-TICT)", 2024, Science Advances
  • "Alteration in the Plasma Concentrations of Endogenous Organic Anion-Transporting Polypeptide 1B Biomarkers in Patients with Non-Small Cell Lung Cancer Treated with Paclitaxel", 2020, Drug Metabolism and Disposition

Kusuhara frequently publishes in several scientific venues, including:

  • Drug Metabolism and Disposition
  • Drug Metabolism and Pharmacokinetics
  • bioRxiv (Cold Spring Harbor Laboratory)
  • arXiv (Cornell University)
  • Clinical Pharmacology & Therapeutics

Collaborations are an important aspect of Kusuhara's research environment. The most frequent coauthors include Tadahaya Mizuno, Kazuya Maeda, Yuichi Sugiyama, Katsuhisa Morita, and Shumpei Nemoto, highlighting an active research network across multiple projects.

Best Publications

  • Polymorphisms of OATP-C (SLC21A6) and OAT3 (SLC22A8) genes: consequences for pravastatin pharmacokinetics.

    Yohei Nishizato;Ichiro Ieiri;Hiroshi Suzuki;Miyuki Kimura

  • Molecular Cloning and Characterization of a New Multispecific Organic Anion Transporter from Rat Brain

    Hiroyuki Kusuhara;Takashi Sekine;Naoko Utsunomiya-Tate;Minoru Tsuda

  • Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta.

    Seok Ho Cha;Takashi Sekine;Hiroyuki Kusuhara;Hiroyuki Kusuhara;Erkang Yu

  • Involvement of Organic Cation Transporter 1 in Hepatic and Intestinal Distribution of Metformin

    De-Sheng Wang;Johan W. Jonker;Yukio Kato;Hiroyuki Kusuhara

  • Physiologically Based Pharmacokinetic Modeling to Predict Transporter-Mediated Clearance and Distribution of Pravastatin in Humans

    Takao Watanabe;Hiroyuki Kusuhara;Kazuya Maeda;Yoshihisa Shitara

  • Kinetic Analysis of the Cooperation of P-Glycoprotein (P-gp/Abcb1) and Breast Cancer Resistance Protein (Bcrp/Abcg2) in Limiting the Brain and Testis Penetration of Erlotinib, Flavopiridol, and Mitoxantrone

    Hiroshi Kodaira;Hiroyuki Kusuhara;Junko Ushiki;Eiichi Fuse

  • Functional involvement of multidrug resistance-associated protein 4 (MRP4/ABCC4) in the renal elimination of the antiviral drugs adefovir and tenofovir.

    Tomoki Imaoka;Hiroyuki Kusuhara;Masashi Adachi;John D. Schuetz

  • Functional Characterization of Rat Brain-specific Organic Anion Transporter (Oatp14) at the Blood-Brain Barrier HIGH AFFINITY TRANSPORTER FOR THYROXINE

    Daisuke Sugiyama;Hiroyuki Kusuhara;Hirokazu Taniguchi;Shumpei Ishikawa

  • Cyclosporin A and its analogs inhibit hepatitis B virus entry into cultured hepatocytes through targeting a membrane transporter, sodium taurocholate cotransporting polypeptide (NTCP)

    Koichi Watashi;Ann Sluder;Takuji Daito;Takuji Daito;Satoko Matsunaga

  • Characterization of uremic toxin transport by organic anion transporters in the kidney.

    Tsuneo Deguchi;Hiroyuki Kusuhara;Akira Takadate;Hitoshi Endou

  • Involvement of BCRP (ABCG2) in the Biliary Excretion of Pitavastatin

    Masaru Hirano;Kazuya Maeda;Soichiro Matsushima;Yoshitane Nozaki

  • Active efflux across the blood-brain barrier: role of the solute carrier family.

    Hiroyuki Kusuhara;Yuichi Sugiyama

  • Evaluation and identification of hepatitis B virus entry inhibitors using HepG2 cells overexpressing a membrane transporter NTCP.

    Masashi Iwamoto;Koichi Watashi;Koichi Watashi;Senko Tsukuda;Hussein Hassan Aly

  • In vitro-in vivo extrapolation of transporter-mediated clearance in the liver and kidney.

    Hiroyuki Kusuhara;Yuichi Sugiyama

  • Effect of breast cancer resistance protein (Bcrp/Abcg2) on the disposition of phytoestrogens.

    Junichi Enokizono;Hiroyuki Kusuhara;Yuichi Sugiyama

  • Characterization of the Efflux Transport of 17β-Estradiol-d-17β-glucuronide from the Brain across the Blood-Brain Barrier

    Daisuke Sugiyama;Hiroyuki Kusuhara;Yoshihisa Shitara;Takaaki Abe

  • Competitive Inhibition of the Luminal Efflux by Multidrug and Toxin Extrusions, but Not Basolateral Uptake by Organic Cation Transporter 2, Is the Likely Mechanism Underlying the Pharmacokinetic Drug-Drug Interactions Caused by Cimetidine in the Kidney

    Sumito Ito;Hiroyuki Kusuhara;Miyu Yokochi;Junko Toyoshima

  • Quantitative Evaluation of the Therapeutic Effects of Antibiotics Using Silkworms Infected with Human Pathogenic Microorganisms

    Hiroshi Hamamoto;Kenji Kurokawa;Chikara Kaito;Koushirou Kamura

  • Role of transporters in the tissue-selective distribution and elimination of drugs: transporters in the liver, small intestine, brain and kidney.

    Hiroyuki Kusuhara;Yuichi Sugiyama

  • Functional characterization of rat brain-specific organic anion transporter (Oatp14) at the blood-brain barrier. High affinity transporter for thyroxine. Vol. 278 (2003) 43489-43495

    Daisuke Sugiyama;Hiroyuki Kusuhara;Hirokazu Taniguchi;Shumpei Ishikawa

Frequent Co-Authors

Yuichi Sugiyama
Yuichi Sugiyama University of Tokyo
Hitoshi Endou
Hitoshi Endou Kyorin University
Hiroshi Suzuki
Hiroshi Suzuki Obihiro University of Agriculture and Veterinary Medicine
John D. Schuetz
John D. Schuetz St. Jude Children's Research Hospital
Yasuyoshi Watanabe
Yasuyoshi Watanabe Osaka Metropolitan University
Tetsuya Suhara
Tetsuya Suhara National Institutes for Quantum and Radiological Science and Technology
Yoshinori Moriyama
Yoshinori Moriyama Okayama University
Kozo Takayama
Kozo Takayama Josai University
Hiroshi Ito
Hiroshi Ito Fukushima Medical University
Koichi Watashi
Koichi Watashi National Institute of Infectious Diseases

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