What is she best known for?
The fields of study she is best known for:
- Gene
- Enzyme
- Internal medicine
Kathleen M. Giacomini mostly deals with Pharmacology, Transporter, Biochemistry, Organic cation transport proteins and Genetics.
The study incorporates disciplines such as Pharmacogenetics and Kidney in addition to Pharmacology.
Her work deals with themes such as Xenobiotic, Drug development, Efflux and Toxicity, which intersect with Transporter.
She interconnects Metformin, Internal medicine, Membrane potential and Endocrinology in the investigation of issues within Organic cation transport proteins.
Kathleen M. Giacomini usually deals with Pharmacokinetics and limits it to topics linked to Kidney metabolism and Renal Elimination and SLC47A2.
Her Drug research includes elements of Quantitative structure–activity relationship, Bioinformatics, Chemical space and In silico.
Her most cited work include:
- Membrane transporters in drug development. (2257 citations)
- Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action. (736 citations)
- Effect of genetic variation in the organic cation transporter 1, OCT1, on metformin pharmacokinetics. (370 citations)
What are the main themes of her work throughout her whole career to date?
Kathleen M. Giacomini focuses on Biochemistry, Pharmacology, Transporter, Internal medicine and Genetics.
Biochemistry and Choroid plexus are frequently intertwined in her study.
Her Pharmacology study incorporates themes from Metformin, Kidney and Organic cation transport proteins.
The Metformin study combines topics in areas such as Pharmacogenetics and Type 2 diabetes.
Her Transporter study frequently intersects with other fields, such as Drug development.
Her Internal medicine research is multidisciplinary, relying on both Endocrinology and Oncology.
She most often published in these fields:
- Biochemistry (26.81%)
- Pharmacology (26.54%)
- Transporter (21.45%)
What were the highlights of her more recent work (between 2016-2021)?
- Pharmacology (26.54%)
- Transporter (21.45%)
- Drug (12.33%)
In recent papers she was focusing on the following fields of study:
Kathleen M. Giacomini spends much of her time researching Pharmacology, Transporter, Drug, Drug development and Biochemistry.
Her research in Pharmacology intersects with topics in Metformin, Uric acid, Thiamine transporter, Organic cation transport proteins and Organic anion transporter 1.
Her study in Organic cation transport proteins focuses on SLC47A1 in particular.
Her Transporter research includes themes of Protein structure, Carnitine and Function.
Her Drug study combines topics from a wide range of disciplines, such as Renal drug, Pharmacokinetics and Excipient.
Her studies in Drug development integrate themes in fields like Clinical trial, IC50, Safety monitoring, Membrane Transport Modulators and Computational biology.
Between 2016 and 2021, her most popular works were:
- Transporters in Drug Development: 2018 ITC Recommendations for Transporters of Emerging Clinical Importance (72 citations)
- Transporters Involved in Metformin Pharmacokinetics and Treatment Response (52 citations)
- Clinical Probes and Endogenous Biomarkers as Substrates for Transporter Drug-Drug Interaction Evaluation: Perspectives From the International Transporter Consortium (49 citations)
In her most recent research, the most cited papers focused on:
- Gene
- Enzyme
- Internal medicine
Her primary areas of investigation include Transporter, Pharmacology, Drug development, Organic cation transport proteins and Organic anion transporter 1.
In her work, Type 2 diabetes and Pharmacogenetics is strongly intertwined with Metformin, which is a subfield of Pharmacology.
Her Drug development research is multidisciplinary, incorporating elements of Abcg2, Pharmacogenomic Variants, Organic anion-transporting polypeptide, Membrane Transport Modulators and Computational biology.
Her studies deal with areas such as Docking, Molecular Docking Simulation, HEK 293 cells, In silico and Drug discovery as well as Organic cation transport proteins.
Her Organic anion transporter 1 research is within the category of Biochemistry.
Her Renal physiology study in the realm of Biochemistry interacts with subjects such as Glutathione disulfide.
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