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D-Index & Metrics

Biology and Biochemistry

D-Index
45
Citations
13357
World Ranking
19045
National Ranking
7773

Overview

Rollie J. Clem is a researcher affiliated with Kansas State University in the United States, with contributions across various fields related to biology and medicine. Their work primarily addresses topics within medicine, agricultural and biological sciences, and biochemistry, genetics, and molecular biology. This multidisciplinary approach reflects a focus on both fundamental biological processes and applied medical research.

The scientist's research subfields include public health, environmental and occupational health, insect science, molecular biology, infectious diseases, and immunology. These domains intersect in their investigations into vector-borne diseases and the immune responses of invertebrates, indicating a detailed examination of disease transmission and host-pathogen interactions.

The main topics of Rollie J. Clem's research encompass:

  • Mosquito-borne diseases and control
  • Insect symbiosis and bacterial influences
  • Viral infections and vectors
  • Insect resistance and genetics
  • Invertebrate immune response mechanisms
  • Viral infectious diseases and gene expression in insects
  • Fibroblast growth factor research

Rollie J. Clem has a variety of recent publications, demonstrating ongoing engagement with entomological virology and vector biology. Notable papers include:

  • Extreme infectious titer variability in individual Aedes aegypti mosquitoes infected with Sindbis virus is associated with both differences in virus population structure and dramatic disparities in specific infectivity (2024, PLoS Pathogens)
  • Factors Affecting Arbovirus Midgut Escape in Mosquitoes (2023, Pathogens)
  • Investigation of Biological Factors Contributing to Individual Variation in Viral Titer after Oral Infection of Aedes aegypti Mosquitoes by Sindbis Virus (2022, Viruses)
  • Expressing the Pro-Apoptotic Reaper Protein via Insertion into the Structural Open Reading Frame of Sindbis Virus Reduces the Ability to Infect Aedes aegypti Mosquitoes (2022, Viruses)
  • Infection of Aedes aegypti Mosquitoes with Midgut-Attenuated Sindbis Virus Reduces, but Does Not Eliminate, Disseminated Infection (2021, Journal of Virology)

The distribution of publications reveals consistent contributions to the journal Viruses, along with other journals such as PLoS Pathogens, Pathogens, and the Journal of Virology. This reflects the scientist's focus on virology, particularly in the context of mosquito-borne viruses.

Rollie J. Clem frequently collaborates with specific researchers in their field. These coauthors include:

  • Alexis Carpenter
  • Peter Hodoameda
  • Scott R. Santos
  • Robert E. Ditter
  • Gregory D. Ebel

Their collaborative network suggests interdisciplinary work bridging virology, entomology, and molecular biology. Overall, Rollie J. Clem's scientific contributions focus heavily on the dynamics of virus-mosquito interactions, immune mechanisms in insects, and factors influencing arbovirus transmission.

Best Publications

  • Conversion of Bcl-2 to a Bax-like Death Effector by Caspases

    Emily H.-Y. Cheng;Emily H.-Y. Cheng;David G. Kirsch;David G. Kirsch;Rollie J. Clem;Rollie J. Clem;Rajani Ravi;Rajani Ravi

  • An apoptosis-inhibiting baculovirus gene with a zinc finger-like motif.

    N E Crook;R J Clem;L K Miller

  • Prevention of Apoptosis by a Baculovirus Gene During Infection of Insect Cells

    Rollie J. Clem;Marcus Fechheimer;Lois K. Miller

  • A conserved family of cellular genes related to the baculovirus iap gene and encoding apoptosis inhibitors.

    C S Duckett;V E Nava;R W Gedrich;R J Clem

  • An apoptosis-inhibiting gene from a nuclear polyhedrosis virus encoding a polypeptide with Cys/His sequence motifs.

    M J Birnbaum;R J Clem;L K Miller

  • Control of programmed cell death by the baculovirus genes p35 and iap.

    R J Clem;L K Miller

  • Modulation of cell death by Bcl-XL through caspase interaction.

    Rollie J. Clem;Rollie J. Clem;Emily H.-Y. Cheng;Emily H.-Y. Cheng;Christopher L. Karp;David G. Kirsch

  • Hid, Rpr and Grim negatively regulate DIAP1 levels through distinct mechanisms

    Soon Ji Yoo;Jun R. Huh;Israel R. Muro;Hong Yu

  • Tissue Barriers to Arbovirus Infection in Mosquitoes.

    Alexander Franz;Asher Kantor;A. Passarelli;Rollie Clem

  • Apoptosis reduces both the in vitro replication and the in vivo infectivity of a baculovirus.

    R J Clem;L K Miller

  • Multifaceted biological insights from a draft genome sequence of the tobacco hornworm moth, Manduca sexta

    Michael R. Kanost;Estela L. Arrese;Xiaolong Cao;Yun Ru Chen

  • Pathogenomics of Culex quinquefasciatus and Meta-Analysis of Infection Responses to Diverse Pathogens

    Lyric C. Bartholomay;Robert M. Waterhouse;Robert M. Waterhouse;Robert M. Waterhouse;George F. Mayhew;Corey L. Campbell

  • The Drosophila DIAP1 protein is required to prevent accumulation of a continuously generated, processed form of the apical caspase DRONC.

    Israel Muro;Bruce A. Hay;Rollie J. Clem

  • Baculoviruses and apoptosis: the good, the bad, and the ugly.

    R J Clem

  • Herpesvirus saimiri encodes a functional homolog of the human bcl-2 oncogene.

    V. E. Nava;E. H.-Y. Cheng;M. Veliuona;S. Zou

  • The role of apoptosis in defense against baculovirus infection in insects.

    R. J. Clem

  • Baculoviruses and apoptosis: a diversity of genes and responses.

    Rollie J Clem

  • Sindbis Virus Induces Apoptosis through a Caspase-Dependent, CrmA-Sensitive Pathway

    Victor E. Nava;Antony Rosen;Michael A. Veliuona;Rollie J. Clem

  • c-IAP1 Is Cleaved by Caspases to Produce a Proapoptotic C-terminal Fragment

    Rollie J. Clem;Ting Ting Sheu;Bettina W.M. Richter;Wei Wu He

  • Insect defenses against virus infection: the role of apoptosis.

    Thomas E Clarke;Rollie J Clem

Frequent Co-Authors

Lois K. Miller
Lois K. Miller University of Georgia
J. Marie Hardwick
J. Marie Hardwick Johns Hopkins University
George F. Rohrmann
George F. Rohrmann Oregon State University
Robert M. Waterhouse
Robert M. Waterhouse Swiss Institute of Bioinformatics
Emily H. Cheng
Emily H. Cheng Memorial Sloan Kettering Cancer Center
Evgeny M. Zdobnov
Evgeny M. Zdobnov Swiss Institute of Bioinformatics
Marc A. T. Muskavitch
Marc A. T. Muskavitch Biogen (United States)
Michael B. Kastan
Michael B. Kastan Duke University
Carol D. Blair
Carol D. Blair Colorado State University
Bruce A. Hay
Bruce A. Hay California Institute of Technology

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