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Best Scientists
2025
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Biology and Biochemistry
USA
2026

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Best Scientists

D-Index
237
Citations
263938
World Ranking
75
National Ranking
53

Biology and Biochemistry

D-Index
238
Citations
272544
World Ranking
12
National Ranking
10

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in United States Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Biology and Biochemistry in United States Leader Award
  • 2023 - Research.com Biology and Biochemistry in United States Leader Award
  • 2022 - Research.com Biology and Biochemistry in United States Leader Award
  • 2005 - Member of the National Academy of Sciences
  • 2002 - Member of the National Academy of Medicine (NAM)
  • 1999 - Fellow of the American Academy of Arts and Sciences
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Craig B. Thompson is affiliated with the Memorial Sloan Kettering Cancer Center in the United States. Their research has contributed extensively to the fields of biochemistry, genetics, molecular biology, and medicine, with a strong focus on molecular biology, cancer research, oncology, immunology, and physiology.

The primary topics covered in their work include:

  • Cancer, Hypoxia, and Metabolism
  • RNA modifications and cancer
  • Mitochondrial Function and Pathology
  • Metabolism, Diabetes, and Cancer
  • Epigenetics and DNA Methylation
  • Pancreatic and Hepatic Oncology Research
  • Cancer Cells and Metastasis

Frequent publication venues for Thompson's work include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • Proceedings of the National Academy of Sciences
  • Nature
  • The EMBO Journal

Notable recent publications are:

  • "The hallmarks of cancer metabolism: Still emerging," 2022, Cell Metabolism
  • "Oncogenic activation of PI3K-AKT-mTOR signaling suppresses ferroptosis via SREBP-mediated lipogenesis," 2020, Proceedings of the National Academy of Sciences
  • "Impaired mitochondrial oxidative phosphorylation limits the self-renewal of T cells exposed to persistent antigen," 2020, Nature Immunology
  • "Proline biosynthesis is a vent for TGFβ-induced mitochondrial redox stress," 2020, The EMBO Journal
  • "Mitochondrial NADP(H) generation is essential for proline biosynthesis," 2021, Science

Frequent coauthors with whom Thompson has collaborated include:

  • Justin R. Cross
  • Natalya N. Pavlova
  • Bryan H. King
  • Scott W. Lowe
  • Simon Schwörer

Throughout their career, Thompson has been recognized by various professional organizations. They were named a Member of the National Academy of Sciences in 2005 and a Member of the National Academy of Medicine in 2002. In 1999, they became a Fellow of the American Academy of Arts and Sciences and are also a Member of the Association of American Physicians.

Best Publications

  • Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

    Matthew G. Vander Heiden;Lewis C. Cantley;Craig B. Thompson

  • Apoptosis in the pathogenesis and treatment of disease

    Craig B. Thompson

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • The Emerging Hallmarks of Cancer Metabolism

    Natalya N. Pavlova;Craig B. Thompson

  • Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death

    Michael C. Wei;Michael C. Wei;Wei-Xing Zong;Emily H.-Y. Cheng;Tullia Lindsten

  • THE BIOLOGY OF CANCER: METABOLIC REPROGRAMMING FUELS CELL GROWTH AND PROLIFERATION

    Ralph J. DeBerardinis;Julian J. Lum;Georgia Hatzivassiliou;Craig B. Thompson

  • Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

    Lenny Dang;David W. White;Stefan Gross;Bryson D. Bennett

  • bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

    Lawrence H. Boise;Maribel González-García;Christina E. Postema;Liyun Ding

  • An inhibitor of Bcl-2 family proteins induces regression of solid tumours

    Tilman Oltersdorf;Steven W. Elmore;Alexander R. Shoemaker;Robert C. Armstrong

  • Lymphoproliferative Disorders with Early Lethality in Mice Deficient in Ctla-4

    Paul Waterhouse;Josef M. Penninger;Emma Timms;Andrew Wakeham

  • Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate

    Patrick S. Ward;Craig B. Thompson

  • Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation.

    Maria E. Figueroa;Omar Abdel-Wahab;Chao Lu;Patrick S. Ward

  • Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

    Daniel J. Klionsky;Hagai Abeliovich;Patrizia Agostinis;Devendra K. Agrawal

  • Bad, a heterodimeric partner for Bcl-xL and Bcl-2, displaces bax and promotes cell death

    Elizabeth Yang;Jiping Zha;Jennifer Jockel;Lawrence H Boise

  • Beyond aerobic glycolysis : Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis

    Ralph J. DeBerardinis;Anthony Mancuso;Evgueni Daikhin;Ilana Nissim

  • CTLA-4 can function as a negative regulator of T cell activation

    Theresa L. Walunas;Deborah J. Lenschow;Christina Y. Bakker;Peter S. Linsley

  • Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-α prolyl hydroxylase

    Mary A. Selak;Sean M. Armour;Elaine D. MacKenzie;Houda Boulahbel

  • CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanisms

    Richard V. Parry;Jens M. Chemnitz;Kenneth A. Frauwirth;Anthony R. Lanfranco

  • The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate

    Patrick S. Ward;Jay Patel;David R. Wise;Omar Abdel-Wahab

  • ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation

    Kathryn E. Wellen;Georgia Hatzivassiliou;Uma M. Sachdeva;Thi V. Bui

Frequent Co-Authors

Tullia Lindsten
Tullia Lindsten Memorial Sloan Kettering Cancer Center
Carl H. June
Carl H. June University of Pennsylvania
Lawrence H. Boise
Lawrence H. Boise Emory University
Chao Lu
Chao Lu Hong Kong Polytechnic University
Justin R. Cross
Justin R. Cross Memorial Sloan Kettering Cancer Center
Wei-Xing Zong
Wei-Xing Zong Rutgers, The State University of New Jersey
Laurence A. Turka
Laurence A. Turka Harvard University
Jeffrey C. Rathmell
Jeffrey C. Rathmell Vanderbilt University Medical Center
Joshua D. Rabinowitz
Joshua D. Rabinowitz Princeton University

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