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Biology and Biochemistry

D-Index
61
Citations
38077
World Ranking
11080
National Ranking
4789

Overview

Tullia Lindsten is affiliated with the Memorial Sloan Kettering Cancer Center in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a notable specialization in molecular biology and cancer research. The work covers several key topics including RNA modifications and cancer, microRNA in disease regulation, circular RNAs in diseases, mitochondrial function and pathology, and the interplay of cancer, hypoxia, and metabolism.

Their published papers reflect these thematic areas. Recent papers include:

  • Inducible and reversible inhibition of miRNA-mediated gene repression in vivo, 2021, eLife
  • VDAC2 and Bak scarcity in liver mitochondria enables targeting hepatocarcinoma while sparing hepatocytes, 2025, Nature Communications
  • Inducible and reversible inhibition of miRNA-mediated gene repression in vivo, 2021, bioRxiv (Cold Spring Harbor Laboratory)

These papers represent contributions to understanding gene repression mechanisms mediated by microRNAs and mitochondrial roles in liver cancer targeting, spanning peer-reviewed journals and preprint archives.

The scientist has frequently collaborated with several researchers, including:

  • Craig B. Thompson (3 coauthored works)
  • Gaspare La Rocca (2 coauthored works)
  • Bryan H. King (2 coauthored works)
  • Bing Shui (2 coauthored works)
  • Xiaoyi Li (2 coauthored works)

Publication venues where Tullia Lindsten's work has appeared include:

  • eLife
  • Nature Communications
  • bioRxiv (Cold Spring Harbor Laboratory)

Lindsten's research scope is situated within molecular biology contexts related to cancer, emphasizing regulatory RNA molecules and mitochondrial functions that affect disease progression. Their work intersects genetic regulatory mechanisms with pathological insights important to cancer metabolism and cellular environment adaptations.

Best Publications

  • Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death

    Michael C. Wei;Michael C. Wei;Wei-Xing Zong;Emily H.-Y. Cheng;Tullia Lindsten

  • bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

    Lawrence H. Boise;Maribel González-García;Christina E. Postema;Liyun Ding

  • BCL-2, BCL-XL Sequester BH3 Domain-Only Molecules Preventing BAX- and BAK-Mediated Mitochondrial Apoptosis

    Emily H.-Y.A Cheng;Michael C Wei;Solly Weiler;Richard A Flavell

  • Growth factor regulation of autophagy and cell survival in the absence of apoptosis

    Julian J. Lum;Daniel E. Bauer;Mei Kong;Marian H. Harris

  • The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues.

    Tullia Lindsten;Andrea J. Ross;Ayala King;Wei Xing Zong

  • CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-xL

    Lawrence H. Boise;Andy J. Minn;Patricia J. Noel;Carl H. June

  • tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c

    Michael C. Wei;Tullia Lindsten;Vamsi K. Mootha;Solly Weiler

  • Effector and memory CD8 + T cell fate coupled by T-bet and eomesodermin

    Andrew M Intlekofer;Naofumi Takemoto;E John Wherry;E John Wherry;Sarah A Longworth

  • Control of Effector CD8+ T Cell Function by the Transcription Factor Eomesodermin

    Erika L. Pearce;Alan C. Mullen;Gislâine A. Martins;Connie M. Krawczyk

  • BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak

    Wei-Xing Zong;Tullia Lindsten;Andrea J. Ross;Grant R. MacGregor

  • CD28 activation pathway regulates the production of multiple T-cell-derived lymphokines/cytokines

    Craig B. Thompson;Tullia Lindsten;Jeffrey A. Ledbetter;Steven L. Kunkel

  • The Transcription Factors T-bet and Eomes Control Key Checkpoints of Natural Killer Cell Maturation

    Scott M. Gordon;Julie Chaix;Levi J. Rupp;Junmin Wu

  • Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis

    Wei-Xing Zong;Chi Li;Georgia Hatzivassiliou;Tullia Lindsten

  • A third type of murine T-cell receptor gene

    Yueh-hsiu Chien;Daniel M. Becker;Tullia Lindsten;Maki Okamura

  • Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation.

    Mondira Kundu;Tullia Lindsten;Chia Ying Yang;Junmin Wu

  • Characterization of XIAP-Deficient Mice

    Helena Harlin;Stephanie Birkey Reffey;Colin S. Duckett;Tullia Lindsten

  • T-cell proliferation involving the CD28 pathway is associated with cyclosporine-resistant interleukin 2 gene expression

    Carl H. June;Jeffrey A. Ledbetter;Marjorie M. Gillespie;Tullia Lindsten

  • Effects of CD28 costimulation on long-term proliferation of CD4+ T cells in the absence of exogenous feeder cells.

    B L Levine;W B Bernstein;M Connors;N Craighead

  • Anomalous type 17 response to viral infection by CD8+ T cells lacking T-bet and eomesodermin.

    Andrew M. Intlekofer;Arnob Banerjee;Naofumi Takemoto;Scott M. Gordon

  • Characterization of CTLA-4 structure and expression on human T cells

    T Lindsten;K P Lee;E S Harris;B Petryniak

Frequent Co-Authors

Craig B. Thompson
Craig B. Thompson Memorial Sloan Kettering Cancer Center
Carl H. June
Carl H. June University of Pennsylvania
Mark M. Davis
Mark M. Davis Stanford University
Wei-Xing Zong
Wei-Xing Zong Rutgers, The State University of New Jersey
Jeffrey M. Leiden
Jeffrey M. Leiden Harvard University
Yueh-hsiu Chien
Yueh-hsiu Chien Stanford University
Steven L. Reiner
Steven L. Reiner Columbia University
Joshua L. Dunaief
Joshua L. Dunaief University of Pennsylvania
Jeffrey A. Ledbetter
Jeffrey A. Ledbetter University of Washington
Jean Bennett
Jean Bennett University of Pennsylvania

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