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Immunology

D-Index
83
Citations
30970
World Ranking
1423
National Ranking
725

Overview

Steven L. Reiner is affiliated with Columbia University in the United States. Their research spans multiple domains within immunology, microbiology, and medicine, focusing primarily on immune responses, cancer immunotherapy, and related molecular mechanisms.

Their main fields of study include:

  • Immunology and Microbiology
  • Medicine

Within these, subfields of particular focus are:

  • Immunology
  • Oncology
  • Molecular Biology
  • Genetics
  • Pulmonary and Respiratory Medicine

Key topics covered by their research include:

  • Cancer Immunotherapy and Biomarkers
  • Immune Cell Function and Interaction
  • Immunotherapy and Immune Responses
  • T-cell and B-cell Immunology
  • CAR-T cell therapy research
  • IL-33, ST2, and ILC Pathways
  • Gut microbiota and health

Recent publications illustrate the breadth and depth of their scientific contributions:

  • "Microbiota imbalance induced by dietary sugar disrupts immune-mediated protection from metabolic syndrome," 2022, Cell
  • "Inhibitory signaling sustains a distinct early memory CD8 + T cell precursor that is resistant to DNA damage," 2021, Science Immunology
  • "The CD58-CD2 axis is co-regulated with PD-L1 via CMTM6 and shapes anti-tumor immunity," 2023, Cancer Cell
  • "Single-cell RNA sequencing reveals distinct T cell populations in immune-related adverse events of checkpoint inhibitors," 2022, Cell Reports Medicine
  • "PD-1 blockade increases the self-renewal of stem-like CD8 T cells to compensate for their accelerated differentiation into effectors," 2023, Science Immunology

Frequent coauthors collaborating on these works include:

  • Brian S. Henick
  • Rohan Maniar
  • Peter H. Wang
  • Naiyer A. Rizvi
  • Robert S. Washburn

Their research is published regularly in venues such as:

  • Science Immunology
  • Cell
  • Cancer Cell
  • Cell Reports Medicine
  • Cancers

Best Publications

  • The lineage decisions of helper T cells

    Kenneth M. Murphy;Steven L. Reiner

  • The regulation of immunity to Leishmania major.

    Steven L Reiner;Richard M Locksley

  • Effector and memory CD8 + T cell fate coupled by T-bet and eomesodermin

    Andrew M Intlekofer;Naofumi Takemoto;E John Wherry;E John Wherry;Sarah A Longworth

  • Control of Effector CD8+ T Cell Function by the Transcription Factor Eomesodermin

    Erika L. Pearce;Alan C. Mullen;Gislâine A. Martins;Connie M. Krawczyk

  • Role of T-bet in Commitment of TH1 Cells Before IL-12-Dependent Selection

    Alan C. Mullen;Frances A. High;Anne S. Hutchins;Hubert W. Lee

  • Asymmetric T lymphocyte division in the initiation of adaptive immune responses.

    John T. Chang;Vikram R. Palanivel;Ichiko Kinjyo;Felix Schambach

  • Helper T Cell Differentiation Is Controlled by the Cell Cycle

    Jennifer J. Bird;Daniel R. Brown;Alan C. Mullen;Naomi H. Moskowitz

  • Progenitor and terminal subsets of CD8+ T cells cooperate to contain chronic viral infection.

    Michael A. Paley;Daniela C. Kroy;Pamela M. Odorizzi;Jonathan B. Johnnidis

  • The Transcription Factors T-bet and Eomes Control Key Checkpoints of Natural Killer Cell Maturation

    Scott M. Gordon;Julie Chaix;Levi J. Rupp;Junmin Wu

  • A Role for the Transcriptional Repressor Blimp-1 in CD8+ T Cell Exhaustion during Chronic Viral Infection

    Haina Shin;Shawn D. Blackburn;Andrew M. Intlekofer;Charlly Kao

  • Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8 + T cell responses during chronic infection

    Charlly Kao;Kenneth J. Oestreich;Michael A. Paley;Alison Crawford

  • VACCINATION WITH DNA ENCODING THE IMMUNODOMINANT LACK PARASITE ANTIGEN CONFERS PROTECTIVE IMMUNITY TO MICE INFECTED WITH LEISHMANIA MAJOR

    Sanjay Gurunathan;David L. Sacks;Daniel R. Brown;Steven L. Reiner

  • CD4+ effector cells default to the Th2 pathway in interferon gamma-deficient mice infected with Leishmania major

    Zhi-En Wang;Steven L. Reiner;Shichun Zheng;Dyana K. Dalton

  • Cutting Edge: The Transcription Factor Eomesodermin Enables CD8+ T Cells To Compete for the Memory Cell Niche

    Arnob Banerjee;Scott M. Gordon;Andrew M. Intlekofer;Michael A. Paley

  • Anomalous type 17 response to viral infection by CD8+ T cells lacking T-bet and eomesodermin.

    Andrew M. Intlekofer;Arnob Banerjee;Naofumi Takemoto;Scott M. Gordon

  • Leishmania promastigotes evade interleukin 12 (IL-12) induction by macrophages and stimulate a broad range of cytokines from CD4+ T cells during initiation of infection.

    S L Reiner;S Zheng;Z E Wang;L Stowring

  • Hlx is induced by and genetically interacts with T-bet to promote heritable T H 1 gene induction

    Alan C. Mullen;Anne S. Hutchins;Frances A. High;Hubert W. Lee

  • Cutting Edge: IL-12 Inversely Regulates T-bet and Eomesodermin Expression during Pathogen-Induced CD8 + T Cell Differentiation

    Naofumi Takemoto;Andrew M. Intlekofer;John T. Northrup;E. John Wherry

  • REGULATION OF SURFACE AND INTRACELLULAR EXPRESSION OF CTLA4 ON MOUSE T CELLS

    M L Alegre;P J Noel;B J Eisfelder;E Chuang

  • Development in motion: helper T cells at work.

    Steven L. Reiner

Frequent Co-Authors

E. John Wherry
E. John Wherry University of Pennsylvania
John T. Chang
John T. Chang University of California, San Diego
Wolfgang Weninger
Wolfgang Weninger Medical University of Vienna
Tullia Lindsten
Tullia Lindsten Memorial Sloan Kettering Cancer Center
Sarah M. Russell
Sarah M. Russell Peter MacCallum Cancer Centre
Christopher A. Hunter
Christopher A. Hunter University of Pennsylvania
Craig B. Thompson
Craig B. Thompson Memorial Sloan Kettering Cancer Center
Janis K. Burkhardt
Janis K. Burkhardt University of Pennsylvania
Joseph C. Sun
Joseph C. Sun Memorial Sloan Kettering Cancer Center
Nigel Killeen
Nigel Killeen University of California, San Francisco

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