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Biology and Biochemistry

D-Index
72
Citations
30999
World Ranking
6133
National Ranking
2877

Overview

Jinfang Zhu is affiliated with the National Institutes of Health in the United States. Their primary research contributions lie within the fields of immunology and microbiology, alongside a significant body of work in medicine.

Their research subfields encompass immunology, molecular biology, oncology, surgery, and physiology. The main topics studied include:

  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • IL-33, ST2, and ILC Pathways
  • Immunotherapy and Immune Responses
  • Eosinophilic Esophagitis
  • Asthma and respiratory diseases
  • Dermatology and Skin Diseases

Frequently publishing in several venues, Jinfang Zhu has contributed notably to:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • The Journal of Immunology
  • Nature Immunology
  • Frontiers in Immunology
  • Immunity

They have coauthored multiple papers with collaborators including Keji Zhao, Rama Krishna Gurram, Gangqing Hu, Difeng Fang, and Mingzhu Zheng.

Several of their recent papers include:

  • CD4 T Helper Cell Subsets and Related Human Immunological Disorders (2020, International Journal of Molecular Sciences)
  • The Transcription Factor T-bet Resolves Memory B Cell Subsets with Distinct Tissue Distributions and Antibody Specificities in Mice and Humans (2020, Immunity)
  • Recent advances in understanding the Th1/Th2 effector choice (2021, Faculty Reviews)
  • Recent advances in understanding the role of IL-4 signaling (2021, Faculty Reviews)
  • Allergen protease-activated stress granule assembly and gasdermin D fragmentation control interleukin-33 secretion (2022, Nature Immunology)

Best Publications

  • Differentiation of Effector CD4 T Cell Populations

    Jinfang Zhu;Hidehiro Yamane;William E. Paul

  • CD4 T cells: fates, functions, and faults

    Jinfang Zhu;William E. Paul

  • Global Mapping of H3K4me3 and H3K27me3 Reveals Specificity and Plasticity in Lineage Fate Determination of Differentiating CD4+ T Cells

    Gang Wei;Lai Wei;Jinfang Zhu;Chongzhi Zang

  • How are T H 2-type immune responses initiated and amplified?

    William E. Paul;Jinfang Zhu

  • A Molecular Roadmap of Reprogramming Somatic Cells into iPS Cells

    Jose M. Polo;Endre Anderssen;Endre Anderssen;Ryan M. Walsh;Benjamin A. Schwarz

  • Conditional deletion of Gata3 shows its essential function in T(H)1-T(H)2 responses.

    Jinfang Zhu;Booki Min;Jane Hu-Li;Cynthia J Watson

  • Heterogeneity and plasticity of T helper cells

    Jinfang Zhu;William E Paul

  • Peripheral CD4+ T‐cell differentiation regulated by networks of cytokines and transcription factors

    Jinfang Zhu;William E. Paul

  • Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5.

    Xiang Ping Yang;Kamran Ghoreschi;Scott M. Steward-Tharp;Jaime Rodriguez-Canales

  • GATA-3 promotes Th2 responses through three different mechanisms: induction of Th2 cytokine production, selective growth of Th2 cells and inhibition of Th1 cell-specific factors

    Jinfang Zhu;Hidehiro Yamane;Javier Cote-Sierra;Liying Guo

  • Steady-state production of IL-4 modulates immunity in mouse strains and is determined by lineage diversity of iNKT cells

    You Jeong Lee;Keli L Holzapfel;Jinfang Zhu;Stephen C Jameson

  • Tissue-resident natural killer (NK) cells are cell lineages distinct from thymic and conventional splenic NK cells

    Dorothy K Sojka;Beatrice Plougastel-Douglas;Liping Yang;Melissa A Pak-Wittel

  • GATA3 controls Foxp3+ regulatory T cell fate during inflammation in mice

    Elizabeth A. Wohlfert;John R. Grainger;Nicolas Bouladoux;Joanne E. Konkel

  • Interleukin 2 plays a central role in Th2 differentiation.

    Javier Cote-Sierra;Gilles Foucras;Liying Guo;Lynda Chiodetti

  • Basophils Produce IL-4 and Accumulate in Tissues after Infection with a Th2-inducing Parasite

    Booki Min;Melanie Prout;Jane Hu-Li;Jinfang Zhu

  • S1P-dependent interorgan trafficking of group 2 innate lymphoid cells supports host defense.

    Yuefeng Huang;Kairui Mao;Xi Chen;Ming An Sun

  • T helper 2 (Th2) cell differentiation, type 2 innate lymphoid cell (ILC2) development and regulation of interleukin-4 (IL-4) and IL-13 production.

    Jinfang Zhu

  • IL-1 family members and STAT activators induce cytokine production by Th2, Th17, and Th1 cells

    Liying Guo;Gang Wei;Jinfang Zhu;Wei Liao

  • Stat5 activation plays a critical role in Th2 differentiation

    Jinfang Zhu;Javier Cote-Sierra;Liying Guo;William E Paul

  • Expression and regulation of intergenic long noncoding RNAs during T cell development and differentiation

    Gangqing Hu;Qingsong Tang;Suveena Sharma;Fang Yu

Frequent Co-Authors

William E. Paul
William E. Paul National Institute of Allergy and Infectious Diseases
Keji Zhao
Keji Zhao National Institutes of Health
Jane Hu-Li
Jane Hu-Li National Institutes of Health
Kairong Cui
Kairong Cui National Institutes of Health
Dragana Jankovic
Dragana Jankovic National Institute of Allergy and Infectious Diseases
Xinyuan Liu
Xinyuan Liu Southern University of Science and Technology
Tarik Möröy
Tarik Möröy University of Montreal
H. Leighton Grimes
H. Leighton Grimes Cincinnati Children's Hospital Medical Center
Bing Sun
Bing Sun Chinese Academy of Sciences
Max Löhning
Max Löhning Charité - University Medicine Berlin

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