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Molecular Biology

D-Index
69
Citations
13777
World Ranking
1489
National Ranking
45

Overview

Tarik Möröy is affiliated with the University of Montreal in Canada and conducts research primarily within the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their work spans a range of subfields including Molecular Biology, Immunology, Genetics, Hematology, and Cancer Research.

Their research addresses several main topics, notably:

  • RNA Research and Splicing
  • Acute Myeloid Leukemia Research
  • RNA modifications and cancer
  • Blood disorders and treatments
  • Immune Cell Function and Interaction
  • Cancer-related molecular mechanisms research
  • Protein Degradation and Inhibitors

Recent papers authored or co-authored by Tarik Möröy include:

  • The transcription factors GFI1 and GFI1B as modulators of the innate and acquired immune response, 2021, Advances in Immunology
  • Multifaceted Actions of GFI1 and GFI1B in Hematopoietic Stem Cell Self-Renewal and Lineage Commitment, 2020, Frontiers in Genetics
  • Crosstalk Between MYC and lncRNAs in Hematological Malignancies, 2020, Frontiers in Oncology
  • Targeting MYC: From understanding its biology to drug discovery, 2020, European Journal of Medicinal Chemistry
  • Targeting the MYC interaction network in B-cell lymphoma via histone deacetylase 6 inhibition, 2022, Oncogene

Frequent collaborators include Jennifer Fraszczak, Kaifee Arman, Hugues Beauchemin, Peiman Shooshtarizadeh, and Riyan Chen.

Tarik Möröy has published multiple articles in several key venues such as:

  • Frontiers in Oncology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Journal of Immunology
  • Communications Biology
  • Cancer Research

Best Publications

  • Features of systemic lupus erythematosus in Dnase1-deficient mice.

    Markus Napirei;Holger Karsunky;Branko Zevnik;Harald Stephan

  • Repression of p15INK4b expression by Myc through association with Miz-1.

    Peter Staller;Karen Peukert;Astrid Kiermaier;Joan Seoane

  • Cyclin D1/bcl-1 cooperates with myc genes in the generation of B-cell lymphoma in transgenic mice.

    H. Lovec;A. Grzeschiczek;M.B. Kowalski;T. Möröy

  • The serine/threonine kinase Pim-1.

    Malte Bachmann;Tarik Möröy

  • Transcription factor Gfi1 regulates self-renewal and engraftment of hematopoietic stem cells

    Hui Zeng;Raif Yücel;Christian Kosan;Ludger Klein‐Hitpass

  • Inflammatory reactions and severe neutropenia in mice lacking the transcriptional repressor Gfi1.

    Holger Karsunky;Hui Zeng;Thorsten Schmidt;Branko Zevnik

  • ZAP-70 expression is a prognostic factor in chronic lymphocytic leukemia

    J Dürig;H Nückel;M Cremer;A Führer

  • Oncogenic activity of cyclin D1 revealed through cooperation with Ha-ras: link between cell cycle control and malignant transformation.

    Lovec H;Sewing A;Lucibello Fc;Müller R

  • Transcription profiling of inner ears from Pou4f3ddl/ddl identifies Gfi1 as a target of the Pou4f3 deafness gene

    Ronna Hertzano;Ronna Hertzano;Mireille Montcouquiol;Sharon Rashi-Elkeles;Rani Elkon

  • Activation of c-myc by woodchuck hepatitis virus insertion in hepatocellular carcinoma

    Tsuey-ying Hsu;Tarik Möröy;Jeanne Etiemble;Anne Louise

  • The Oncogenic Serine/Threonine Kinase Pim-1 Phosphorylates and Inhibits the Activity of Cdc25C-associated Kinase 1 (C-TAK1) A NOVEL ROLE FOR Pim-1 AT THE G2/M CELL CYCLE CHECKPOINT

    Malte Bachmann;Hanjo Hennemann;Pei Xiang Xing;Ingrid Hoffmann

  • GFI1 proteins orchestrate the emergence of haematopoietic stem cells through recruitment of LSD1

    Roshana Thambyrajah;Milena Mazan;Milena Mazan;Rahima Patel;Victoria Moignard

  • The Transcriptional Repressor Gfi1 Affects Development of Early, Uncommitted c-Kit+ T Cell Progenitors and CD4/CD8 Lineage Decision in the Thymus

    Raif Yücel;Holger Karsunky;Ludger Klein-Hitpass;Tarik Möröy

  • GFI1 and GFI1B control the loss of endothelial identity of hemogenic endothelium during hematopoietic commitment.

    Christophe Lancrin;Milena Mazan;Monika Stefanska;Rahima Patel

  • Rearrangement and enhanced expression of c-myc in hepatocellular carcinoma of hepatitis virus infected woodchucks.

    Tarik Möröy;Agnés Marchio;Jeanne Etiemble;Christian Trépo

  • Sulindac sulfide inhibits Ras signaling

    Christian Herrmann;Christoph Block;Christoph Geisen;Kirsten Haas

  • Gfi1:Green Fluorescent Protein Knock-in Mutant Reveals Differential Expression and Autoregulation of the Growth Factor Independence 1 (Gfi1) Gene during Lymphocyte Development

    Raif Yücel;Christian Kosan;Florian Heyd;Tarik Möröy

  • The oncogenic serine/threonine kinase Pim-1 directly phosphorylates and activates the G2/M specific phosphatase Cdc25C.

    Malte Bachmann;Christian Kosan;Pei Xiang Xing;Mathias Montenarh

  • The zinc finger protein Gfi‐1 can enhance STAT3 signaling by interacting with the STAT3 inhibitor PIAS3

    Bernd Rödel;Kamiab Tavassoli;Holger Karsunky;Thorsten Schmidt

  • Expression of a Pim-1 transgene accelerates lymphoproliferation and inhibits apoptosis in lpr/lpr mice

    Tarik Moroy;Antje Grzeschiczek;Sigrid Petzold;Klaus-Ulrich Hartmann

Frequent Co-Authors

Ulrich Dührsen
Ulrich Dührsen University of Duisburg-Essen
Ludger Klein-Hitpass
Ludger Klein-Hitpass University of Duisburg-Essen
H. Leighton Grimes
H. Leighton Grimes Cincinnati Children's Hospital Medical Center
Joop H. Jansen
Joop H. Jansen Radboud University
Martin Eilers
Martin Eilers University of Würzburg
Jaroslaw P. Maciejewski
Jaroslaw P. Maciejewski Cleveland Clinic
Pierre Tiollais
Pierre Tiollais Institut Pasteur
Erich Gulbins
Erich Gulbins University of Duisburg-Essen
Jinfang Zhu
Jinfang Zhu National Institutes of Health

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