2026 Hans Georg Mannherz: Biology and Biochemistry Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Biology and Biochemistry	59	12377	11397	882	826	204	15549

Overview

Hans Georg Mannherz is a researcher affiliated with Ruhr University Bochum in Germany. Their academic work primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a significant focus on Cardiology and Cardiovascular Medicine, as well as Molecular Biology and Immunology.

Their research addresses key topics including Cardiomyopathy and Myosin Studies, Cardiovascular Effects of Exercise, Cellular Mechanics and Interactions, Muscle Physiology and Disorders, Cell Adhesion Molecules Research, Cell Image Analysis Techniques, and Genetics, Aging, and Longevity in Model Organisms.

Among their recent papers, the following have been published in recognized journals:

"Stress activated signalling impaired protein quality control pathways in human hypertrophic cardiomyopathy" (2021), published in International Journal of Cardiology
"Infantile restrictive cardiomyopathy: cTnI-R170G/W impair the interplay of sarcomeric proteins and the integrity of thin filaments" (2020), published in PLoS ONE
"The Interplay between S-Glutathionylation and Phosphorylation of Cardiac Troponin I and Myosin Binding Protein C in End-Stage Human Failing Hearts" (2021), published in Antioxidants
"De Novo Missense Mutations in TNNC1 and TNNI3 Causing Severe Infantile Cardiomyopathy Affect Myofilament Structure and Function and Are Modulated by Troponin Targeting Agents" (2021), published in International Journal of Molecular Sciences
"Deoxyribonuclease 1-Mediated Clearance of Circulating Chromatin Prevents From Immune Cell Activation and Pro-inflammatory Cytokine Production, a Phenomenon Amplified by Low Trap1 Activity: Consequences for Systemic Lupus Erythematosus" (2021), published in Frontiers in Immunology

The most frequent publication venues for their work include:

International Journal of Cardiology
Antioxidants
International Journal of Molecular Sciences
PLoS ONE
Frontiers in Cardiovascular Medicine

Collaborations have been a substantial part of their research with frequent co-authors including:

Roua Hassoun
Andreas Mügge
Nazha Hamdani
Heidi Budde
Kornélia Jaquet

The scholarly output of Hans Georg Mannherz demonstrates a multidisciplinary approach focused on advancing understanding in cardiomyopathy, molecular mechanisms in cardiovascular diseases, and immunological processes. Their work contributes to the comprehension of cellular and molecular changes in heart diseases and related systemic conditions.

Best Publications

Atomic structure of the actin:DNase I complex.

Wolfgang Kabsch;Hans Georg Mannherz;Dietrich Suck;Emil F. Pai

2658
Citations
Features of systemic lupus erythematosus in Dnase1-deficient mice.

Markus Napirei;Holger Karsunky;Branko Zevnik;Harald Stephan

1071
Citations
Structure of gelsolin segment 1-actin complex and the mechanism of filament severing

P. J. McLaughlin;J. T. Gooch;H.-G. Mannherz;A. G. Weeds

774
Citations
Characterization of the endogenous deoxyribonuclease involved in nuclear DNA degradation during apoptosis (programmed cell death).

M.C. Peitsch;B. Polzar;H. Stephan;T. Crompton

700
Citations
Host DNases prevent vascular occlusion by neutrophil extracellular traps

Miguel Jiménez-Alcázar;Chandini Rangaswamy;Rachita Panda;Josephine Bitterling

583
Citations
Cold-induced apoptosis in cultured hepatocytes and liver endothelial cells: mediation by reactive oxygen species.

Ursula Rauen;Bernhard Polzar;Harald Stephan;Hans Georg Mannherz

425
Citations
Arp2/3 complex interactions and actin network turnover in lamellipodia

Frank P L Lai;Malgorzata Szczodrak;Jennifer Block;Jan Faix

378
Citations
Structure of the Rigor Actin-Tropomyosin-Myosin Complex

Elmar Behrmann;Mirco Müller;Pawel A. Penczek;Hans Georg Mannherz

367
Citations
Photorhabdus luminescens Toxins ADP-Ribosylate Actin and RhoA to Force Actin Clustering

Alexander E. Lang;Gudula Schmidt;Andreas Schlosser;Timothy D. Hey

286
Citations
The Interaction of Bovine Pancreatic Deoxyribonuclease I and Skeletal Muscle Actin

Hans Georg Mannherz;Roger S. Goody;Manfred Konrad;Ewa Nowak

263
Citations
Proteins of Contractile Systems

Hans Georg Mannherz;Roger S. Goody

226
Citations
Determining the differences in actin binding by human ADF and cofilin.

Sharon Yeoh;Brian Pope;Hans G Mannherz;Alan Weeds

208
Citations
A specific 1:1 G-actin:DNAase i complex formed by the action of DNAase I on F-actin.

Hans Georg Mannherz;J. Barrington Leigh;Reuben Leberman;H. Pfrang

203
Citations
The apoptosis endonucleases: cleaning up after cell death?

Manuel C. Peitsch;Hans Georg Mannherz;Jürg Tschopp

202
Citations
Actin as target for modification by bacterial protein toxins

Klaus Aktories;Alexander E. Lang;Carsten Schwan;Hans G. Mannherz

191
Citations
Murine serum nucleases--contrasting effects of plasmin and heparin on the activities of DNase1 and DNase1-like 3 (DNase1l3).

Markus Napirei;Sebastian Ludwig;Jamal Mezrhab;Thomas Klöckl

181
Citations
Chromatin breakdown during necrosis by serum Dnase1 and the plasminogen system

Markus Napirei;Swantje Wulf;Hans Georg Mannherz

170
Citations
Cisplatin Nephrotoxicity Is Mediated by Deoxyribonuclease I

Alexei G. Basnakian;Eugene O. Apostolov;Xiaoyan Yin;Markus Napirei

164
Citations
Three-dimensional structure of the complex of skeletal muscle actin and bovine pancreatic DNAse I at 6-A resolution

Dietrich Suck;Wolfgang Kabsch;Hans Georg Mannherz

161
Citations
Impaired DNase1-mediated degradation of neutrophil extracellular traps is associated with acute thrombotic microangiopathies.

M. Jiménez-Alcázar;M. Napirei;R. Panda;E. C. Köhler

156
Citations