Matthias Geyer

Overview

Best Publications

• Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer’s disease

  Carmen Venegas;Sathish Kumar;Bernardo S. Franklin;Tobias Dierkes

  981
  Citations

• The RNA Polymerase II Carboxy-Terminal Domain (CTD) Code

  Dirk Eick;Matthias Geyer

  552
  Citations

• Structure–function relationships in HIV-1 Nef

  Matthias Geyer;Oliver T Fackler;B Matija Peterlin

  520
  Citations

• Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape.

  Paul-Albert Koenig;Hrishikesh Das;Hejun Liu;Beate M. Kümmerer

  414
  Citations

• Activation of Vav by Nef Induces Cytoskeletal Rearrangements and Downstream Effector Functions

  Oliver T Fackler;Wen Luo;Matthias Geyer;Arthur S Alberts

  349
  Citations

• Substrate-assisted catalysis as a mechanism for GTP hydrolysis of p21ras and other GTP-binding proteins.

  Thomas Schweins;Matthias Geyer;Klaus Scheffzek;Arieh Warshel

  332
  Citations

• Formins as effector proteins of Rho GTPases

  Sonja Kühn;Matthias Geyer

  329
  Citations

• The Control of HIV Transcription: Keeping RNA Polymerase II on Track

  Melanie Ott;Matthias Geyer;Qiang Zhou

  324
  Citations

• Fifteen formins for an actin filament: A molecular view on the regulation of human formins

  André Schönichen;Matthias Geyer

  312
  Citations

• Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitors

  Tinghu Zhang;Nicholas Kwiatkowski;Nicholas Kwiatkowski;Calla M Olson;Sarah E Dixon-Clarke

  308
  Citations

• NLRP3 inflammasome assembly is regulated by phosphorylation of the pyrin domain

  Andrea Stutz;Carl-Christian Kolbe;Rainer Stahl;Gabor L. Horvath

  298
  Citations

• Conformational transitions in p21ras and in its complexes with the effector protein Raf-RBD and the GTPase activating protein GAP.

  Matthias Geyer;Thomas Schweins;Christian Herrmann;Thomas Prisner

  284
  Citations

• Brd4 activates P-TEFb for RNA polymerase II CTD phosphorylation

  Friederike Itzen;Ann Katrin Greifenberg;Ann Katrin Greifenberg;Christian Andreas Bösken;Christian Andreas Bösken;Matthias Geyer;Matthias Geyer

  271
  Citations

• CDK12 Inhibition Reverses De Novo and Acquired PARP Inhibitor Resistance in BRCA Wild-Type and Mutated Models of Triple-Negative Breast Cancer.

  Shawn F. Johnson;Cristina Cruz;Ann Katrin Greifenberg;Ann Katrin Greifenberg;Sofia Dust;Sofia Dust

  259
  Citations

• Rational discovery of molecular glue degraders via scalable chemical profiling

  Cristina Mayor-Ruiz;Sophie Bauer;Matthias Brand;Zuzanna Kozicka;Zuzanna Kozicka

  258
  Citations

• Serine-7 but not serine-5 phosphorylation primes RNA polymerase II CTD for P-TEFb recognition

  Nadine Czudnochowski;Christian A. Bösken;Matthias Geyer

  237
  Citations

• GEFs, GAPs, GDIs and effectors: taking a closer (3D) look at the regulation of Ras−related GTP−binding proteins

  Matthias Geyer;Alfred Wittinghofer

  232
  Citations

• FMNL2 drives actin-based protrusion and migration downstream of Cdc42.

  Jennifer Block;Dennis Breitsprecher;Sonja Kühn;Moritz Winterhoff

  227
  Citations

• Tat competes with HEXIM1 to increase the active pool of P-TEFb for HIV-1 transcription

  Matjaz Barboric;Jasper H. N. Yik;Nadine Czudnochowski;Zhiyuan Yang

  210
  Citations

• CDK12 loss in cancer cells affects DNA damage response genes through premature cleavage and polyadenylation.

  Malgorzata Krajewska;Ruben Dries;Andrew V. Grassetti;Sofia Dust

  206
  Citations