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Microbiology

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Molecular Biology

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88
Citations
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783
National Ranking
416

Overview

B. Matija Peterlin is affiliated with the University of California, San Francisco in the United States. Their research primarily spans fields such as Biochemistry, Genetics and Molecular Biology, Immunology and Microbiology, and Medicine. Subfields of focus include Molecular Biology, Virology, Infectious Diseases, Cell Biology, and Immunology.

The core topics in Peterlin's work address Protein Degradation and Inhibitors, HIV Research and Treatment, HIV/AIDS drug development and treatment, Genomics and Chromatin Dynamics, Ubiquitin and proteasome pathways, Cellular transport and secretion, and Immune Cell Function and Interaction.

Peterlin's research output includes publications in several scientific journals and repositories. Notable recent papers include:

  • P-TEFb: The master regulator of transcription elongation, 2023, Molecular Cell
  • HIV-1 Nef interacts with the cyclin K/CDK13 complex to antagonize SERINC5 for optimal viral infectivity, 2021, Cell Reports
  • Proteasomal Inhibition Potentiates Latent HIV Reactivation, 2020, AIDS Research and Human Retroviruses
  • P-TEFb is degraded by Siah1/2 in quiescent cells, 2022, Nucleic Acids Research
  • HIV-1 Nef and CycK:CDK13 antagonize SERINC5 for optimal viral infectivity, 2021, bioRxiv (Cold Spring Harbor Laboratory)

Frequent co-authors collaborating with Peterlin include Koh Fujinaga, Fang Huang, Qingqing Chai, Sunan Li, and Morgan K. Collins. These collaborations have resulted in multiple publications together.

Peterlin has contributed prominently to articles published in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular Cell
  • Cell Reports
  • AIDS Research and Human Retroviruses
  • Nucleic Acids Research

Best Publications

  • Controlling the Elongation Phase of Transcription with P-TEFb

    B. Matija Peterlin;David H. Price

  • Anti-termination of transcription within the long terminal repeat of HIV-1 by tat gene product.

    Shaw Yi Kao;Andrew F. Calman;Paul A Luciw;B. Matija Peterlin

  • HIV Nef is secreted in exosomes and triggers apoptosis in bystander CD4+ T cells.

    Metka Lenassi;Gerard Cagney;Gerard Cagney;Maofu Liao;Tomaž Vaupotič

  • Flavopiridol inhibits P-TEFb and blocks HIV-1 replication.

    Sheng-Hao Chao;Koh Fujinaga;Jon E. Marion;Ran Taube

  • NF-κB Binds P-TEFb to Stimulate Transcriptional Elongation by RNA Polymerase II

    Matjaz Barboric;Matjaz Barboric;Robert M. Nissen;Satoshi Kanazawa;Nabila Jabrane-Ferrat

  • The Cyclin K/Cdk12 complex maintains genomic stability via regulation of expression of DNA damage response genes

    Dalibor Blazek;Jiri Kohoutek;Koen Bartholomeeusen;Eric Johansen

  • Human APOBEC3F Is Another Host Factor That Blocks Human Immunodeficiency Virus Type 1 Replication

    Yong Hui Zheng;Dan Irwin;Takeshi Kurosu;Kenzo Tokunaga

  • Structure–function relationships in HIV-1 Nef

    Matthias Geyer;Oliver T Fackler;B Matija Peterlin

  • Dynamics of Human Immunodeficiency Virus Transcription: P-TEFb Phosphorylates RD and Dissociates Negative Effectors from the Transactivation Response Element

    Koh Fujinaga;Koh Fujinaga;Dan Irwin;Yehong Huang;Ran Taube

  • Elevated levels of mRNA can account for the trans-activation of human immunodeficiency virus.

    B. M. Peterlin;Paul A Luciw;P. J. Barr;M. D. Walker

  • Suberoylanilide Hydroxamic Acid Reactivates HIV From Latently Infected Cells

    Xavier Contreras;Marc Schweneker;Ching-Shih Chen;Joseph M. McCune

  • Human immunodeficiency virus long terminal repeat responds to T-cell activation signals.

    S. E. Tong-Starksen;Paul A Luciw;B. M. Peterlin

  • Charting HIV's remarkable voyage through the cell: Basic science as a passport to future therapy.

    Warner C. Greene;B. Matija Peterlin

  • HIV-1 nef leads to inhibition or activation of T cells depending on its intracellular localization

    Andreas S. Baur;Earl T. Sawai;Paul Dazin;Wendy J. Fantl

  • Tat competes with CIITA for the binding to P-TEFb and blocks the expression of MHC class II genes in HIV infection.

    Satoshi Kanazawa;Takashi Okamoto;B.Matija Peterlin

  • Interactions between HIV1 Nef and Vacuolar ATPase Facilitate the Internalization of CD4

    Xiaobin Lu;Haifeng Yu;Shu-Hui Liu;Frances M Brodsky

  • An In-Depth Comparison of Latency-Reversing Agent Combinations in Various In Vitro and Ex Vivo HIV-1 Latency Models Identified Bryostatin-1+JQ1 and Ingenol-B+JQ1 to Potently Reactivate Viral Gene Expression.

    Gilles Darcis;Anna Kula;Sophie Bouchat;Koh Fujinaga

  • Activation of Vav by Nef Induces Cytoskeletal Rearrangements and Downstream Effector Functions

    Oliver T Fackler;Wen Luo;Matthias Geyer;Arthur S Alberts

  • Trans-activation by HIV-1 Tat via a heterologous RNA binding protein

    Mark J. Selby;B.Matija Peterlin

  • Transcriptional Interference Antagonizes Proviral Gene Expression to Promote HIV Latency

    Tina Lenasi;Xavier Contreras;B. Matija Peterlin

  • Intervening sequence of DNA identified in the structural portion of a mouse beta-globin gene.

    Shirley Marie Tilghman;D. C. Tiemeier;J. G. Seidman;B. M. Peterlin

Frequent Co-Authors

Matthias Geyer
Matthias Geyer University of Bonn
David H. Price
David H. Price University of Iowa
Nevan J. Krogan
Nevan J. Krogan University of California, San Francisco
Oliver T. Fackler
Oliver T. Fackler University Hospital Heidelberg
Takashi Okamoto
Takashi Okamoto Nagoya City University
Yi Zhou
Yi Zhou Harvard University
Leonard I. Zon
Leonard I. Zon Harvard University
Paul A. Luciw
Paul A. Luciw University of California, Davis
Amilcar Tanuri
Amilcar Tanuri Federal University of Rio de Janeiro
Susan R. Ross
Susan R. Ross University of Illinois at Chicago

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