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D-Index & Metrics

Molecular Biology

D-Index
71
Citations
21953
World Ranking
1361
National Ranking
690

Research.com Recognitions

  • 2013 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

David H. Price is affiliated with the University of Iowa in the United States. Their research spans multiple disciplines with a primary focus on biochemistry, genetics, and molecular biology, contributing extensively to the fields of molecular biology and medicine. The subfields that characterize their work include molecular biology, epidemiology, cancer research, oncology, and immunology.

Price's scientific contributions center on several key research topics. These encompass RNA modifications and cancer, genomics and chromatin dynamics, RNA research and splicing, cytomegalovirus and herpesvirus research, herpesvirus infections and treatments, cancer in relation to hypoxia and metabolism, and RNA regulation in disease contexts.

Among the scientist's recent publications are:

  • "MYC assembles and stimulates topoisomerases 1 and 2 in a 'topoisome'" (2021, Molecular Cell)
  • "Differential dependencies of human RNA polymerase II promoters on TBP, TAF1, TFIIB and XPB" (2022, Nucleic Acids Research)
  • "A unified view of the sequence and functional organization of the human RNA polymerase II promoter" (2020, Nucleic Acids Research)
  • "Human cytomegalovirus IE2 drives transcription initiation from a select subset of late infection viral promoters by host RNA polymerase II" (2020, PLoS Pathogens)
  • "DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation" (2023, eLife)

Frequent co-authors of Price's work include Juan F. Santana, Mrutyunjaya Parida, Benjamin M. Spector, Jeffery L. Meier, and Ming Li. These collaborators have contributed to multiple joint publications, highlighting a pattern of ongoing partnerships in their research efforts.

Price's work has appeared regularly in several scientific publication venues. The primary journals and repositories include Nucleic Acids Research, UNC Libraries, PLoS Pathogens, Viruses, and Molecular Cell.

In recognition of contributions to science, Price was named a Fellow of the American Association for the Advancement of Science (AAAS) in 2013.

Best Publications

  • Controlling the Elongation Phase of Transcription with P-TEFb

    B. Matija Peterlin;David H. Price

  • P-TEFb, a cyclin-dependent kinase controlling elongation by RNA polymerase II.

    David H. Price

  • Transcription elongation factor P-TEFb is required for HIV-1 Tat transactivation in vitro

    Yuerong Zhu;Tsafrira Pe’ery;Junmin Peng;Yegnanarayana Ramanathan

  • Control of RNA Polymerase II Elongation Potential by a Novel Carboxyl-terminal Domain Kinase *

    Nick F. Marshall;Junmin Peng;Zhi Xie;David H. Price

  • Flavopiridol inactivates P-TEFb and blocks most RNA polymerase II transcription in vivo.

    Sheng Hao Chao;David H. Price

  • Purification of P-TEFb, a Transcription Factor Required for the Transition into Productive Elongation

    Nick F. Marshall;David H. Price

  • P-TEFb kinase is required for HIV Tat transcriptional activation in vivo and in vitro.

    Helena S.Y. Mancebo;Gary Lee;John Flygare;Joanne Tomassini

  • Identification of multiple cyclin subunits of human P-TEFb

    Junmin Peng;Yuerong Zhu;Jeffrey T. Milton;David H. Price

  • RNA polymerase II elongation control

    Qiang Zhou;Tiandao Li;David H. Price

  • Flavopiridol inhibits P-TEFb and blocks HIV-1 replication.

    Sheng-Hao Chao;Koh Fujinaga;Jon E. Marion;Ran Taube

  • Randomised phase 2 trial of SIR-Spheres plus fluorouracil/leucovorin chemotherapy versus fluorouracil/leucovorin chemotherapy alone in advanced colorectal cancer.

    Guy Van Hazel;Anthony Blackwell;James Anderson;David Price

  • Systematic Analysis of the Protein Interaction Network for the Human Transcription Machinery Reveals the Identity of the 7SK Capping Enzyme

    Célia Jeronimo;Diane Forget;Annie Bouchard;Qintong Li

  • CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1

    Bartlomiej Bartkowiak;Pengda Liu;Hemali P. Phatnani;Nicholas J. Fuda

  • Control of formation of two distinct classes of RNA polymerase II elongation complexes.

    N F Marshall;D H Price

  • SIRFLOX: Randomized Phase III Trial Comparing First-Line mFOLFOX6 (Plus or Minus Bevacizumab) Versus mFOLFOX6 (Plus or Minus Bevacizumab) Plus Selective Internal Radiation Therapy in Patients With Metastatic Colorectal Cancer

    Guy A. van Hazel;Volker Heinemann;Navesh K. Sharma;Michael P.N. Findlay

  • P-TEFb kinase recruitment and function at heat shock loci.

    John T. Lis;Paul Mason;J. Peng;David H. Price

  • Radioembolization of Liver Metastases From Colorectal Cancer Using Yttrium-90 Microspheres With Concomitant Systemic Oxaliplatin, Fluorouracil, and Leucovorin Chemotherapy

    Ricky A. Sharma;Guy A. Van Hazel;Bruno Morgan;David P. Berry

  • Tat modifies the activity of CDK9 to phosphorylate serine 5 of the RNA polymerase II carboxyl-terminal domain during human immunodeficiency virus type 1 transcription

    Meisheng Zhou;Matthew A. Halanski;Michael F. Radonovich;Fatah Kashanchi

  • RNA polymerase II elongation control.

    J. Peng;M. Liu;J. Marion;Y. Zhu

  • Crystal structure of HIV-1 Tat complexed with human P-TEFb.

    Tahir H. Tahirov;Nigar D. Babayeva;Katayoun Varzavand;Jeffrey J. Cooper

Frequent Co-Authors

Junmin Peng
Junmin Peng St. Jude Children's Research Hospital
B. Matija Peterlin
B. Matija Peterlin University of California, San Francisco
Arno L. Greenleaf
Arno L. Greenleaf Duke University
Yi Zhou
Yi Zhou Harvard University
Leonard I. Zon
Leonard I. Zon Harvard University
Olivier Bensaude
Olivier Bensaude École Normale Supérieure
Fatah Kashanchi
Fatah Kashanchi George Mason University
Katherine K. Matthay
Katherine K. Matthay University of California, San Francisco
Michael W. Gray
Michael W. Gray Dalhousie University

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