World's Best Scientists 2026 revealed!

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Immunology

D-Index
90
Citations
28107
World Ranking
1079
National Ranking
582

Genetics

D-Index
90
Citations
27935
World Ranking
1075
National Ranking
517

Medicine

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90
Citations
28123
World Ranking
12256
National Ranking
6277

Overview

Edward K. Wakeland is affiliated with The University of Texas Southwestern Medical Center in United States. Their research primarily focuses on fields within Medicine and Immunology and Microbiology, with a significant number of publications in these areas.

The subfields of study that Wakeland has contributed to include:

  • Immunology
  • Oncology
  • Genetics
  • Molecular Biology
  • Radiology, Nuclear Medicine and Imaging

Wakeland's work addresses a range of topics, notably:

  • Cancer Immunotherapy and Biomarkers
  • Immune Cell Function and Interaction
  • Monoclonal and Polyclonal Antibodies Research
  • Systemic Lupus Erythematosus Research
  • Colorectal Cancer Treatments and Studies
  • Chronic Lymphocytic Leukemia Research
  • Immune Response and Inflammation

Frequent publication venues for Wakeland include:

  • Journal for ImmunoTherapy of Cancer
  • The Oncologist
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Reports
  • Annals of the Rheumatic Diseases

Selected recent papers authored or co-authored by Wakeland are:

  • IRF1 governs the differential interferon-stimulated gene responses in human monocytes and macrophages by regulating chromatin accessibility, 2021, Cell Reports
  • A conserved long noncoding RNA, GAPLINC, modulates the immune response during endotoxic shock, 2021, Proceedings of the National Academy of Sciences
  • Association between body mass index, dosing strategy, and efficacy of immune checkpoint inhibitors, 2021, Journal for ImmunoTherapy of Cancer
  • Loss-of-function variants in SAT1 cause X-linked childhood-onset systemic lupus erythematosus, 2022, Annals of the Rheumatic Diseases
  • Late-Onset Immunotherapy Toxicity and Delayed Autoantibody Changes: Checkpoint Inhibitor-Induced Raynaud's-Like Phenomenon, 2020, The Oncologist

Wakeland collaborates with several frequent co-authors, including:

  • Farjana Fattah
  • David E. Gerber
  • Mitchell S. von Itzstein
  • Jason Y. Park
  • Quan-Zhen Li

Best Publications

  • The Antibacterial Lectin RegIIIγ Promotes the Spatial Segregation of Microbiota and Host in the Intestine

    Shipra Vaishnava;Miwako Yamamoto;Kari M. Severson;Kelly A. Ruhn

  • Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.

    John B. Harley;John B. Harley;John B. Harley;Marta E. Alarcón-Riquelme;Lindsey A. Criswell;Chaim O. Jacob

  • Nomenclature for the major histocompatibility complexes of different species: a proposal

    Jan Klein;Ronald E. Bontrop;Roger L. Dawkins;Henry A. Erlich

  • Personalized Immunomonitoring Uncovers Molecular Networks that Stratify Lupus Patients.

    Romain Banchereau;Seunghee Hong;Brandi Cantarel;Nicole Baldwin

  • Delineating the genetic basis of systemic lupus erythematosus.

    Edward K Wakeland;Kui Liu;Robert R Graham;Timothy W Behrens

  • A Tlr7 translocation accelerates systemic autoimmunity in murine lupus.

    Srividya Subramanian;Katalin Tus;Quan Zhen Li;Andrew Wang

  • Mating patterns in seminatural populations of mice influenced by MHC genotype.

    Wayne K. Potts;C. Jo Manning;C. Jo Manning;Edward K. Wakeland

  • Polygenic control of susceptibility to murine systemic lupus erythematosus

    Laurence Morel;Ulrich H. Rudofsky;Jeffrey A. Longmate;Joel Schiffenbauer;Joel Schiffenbauer

  • The nature and identification of quantitative trait loci: a community's view.

    Oduola Abiola;Joe M. Angel;Philip Avner;Alexander A. Bachmanov

  • Optimal Germinal Center Responses Require a Multistage T Cell:B Cell Adhesion Process Involving Integrins, SLAM-Associated Protein, and CD84

    Jennifer L. Cannons;Hai Qi;Kristina T. Lu;Mala Dutta;Mala Dutta

  • The genetics of complex autoimmune diseases: non-MHC susceptibility genes.

    Amy Wandstrat;Edward Wakeland

  • Genetic reconstitution of systemic lupus erythematosus immunopathology with polycongenic murine strains

    Laurence Morel;Byron P. Croker;Kim R. Blenman;Chandra Mohan

  • Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis

    Anne Hinks;Anne Hinks;Joanna E. Cobb;Joanna E. Cobb;Miranda C. Marion;Sampath Prahalad

  • Speed congenics: a classic technique in the fast lane (relatively speaking).

    Edward Wakeland;Laurence Morel;Karen Achey;Mary Yui

  • Transancestral mapping and genetic load in systemic lupus erythematosus

    Carl D. Langefeld;Hannah C. Ainsworth;Deborah S. Cunninghame Graham;Jennifer A. Kelly

  • The major murine systemic lupus erythematosus susceptibility locus, Sle1, is a cluster of functionally related genes

    Laurence Morel;Kim R. Blenman;Byron P. Croker;Byron P. Croker;Edward K. Wakeland

  • A nonsynonymous functional variant in integrin-alpha(M) (encoded by ITGAM) is associated with systemic lupus erythematosus.

    Swapan K. Nath;Shizhong Han;Xana Kim-Howard;Jennifer A. Kelly

  • Genetic dissection of SLE pathogenesis. Sle1 on murine chromosome 1 leads to a selective loss of tolerance to H2A/H2B/DNA subnucleosomes.

    Chandra Mohan;Elizabeth Alas;Laurence Morel;Ping Yang

  • Association of extensive polymorphisms in the SLAM/CD2 gene cluster with murine lupus.

    Amy E. Wandstrat;Charles Nguyen;Nisha Limaye;Alice Y. Chan

  • Functional dissection of systemic lupus erythematosus using congenic mouse strains.

    Laurence Morel;Chandra Mohan;Ying Yu;Byron P. Croker;Byron P. Croker

  • Communal nesting patterns in mice implicate MHC genes in kin recognition

    C. Jo Manning;C. Jo Manning;Edward K. Wakeland;Wayne K. Potts

Frequent Co-Authors

Quan Zhen Li
Quan Zhen Li The University of Texas Southwestern Medical Center
John B. Harley
John B. Harley United States Department of Veterans Affairs
Judith A. James
Judith A. James Oklahoma Medical Research Foundation
Chandra Mohan
Chandra Mohan University of Houston
Kenneth M. Kaufman
Kenneth M. Kaufman Cincinnati Children's Hospital Medical Center
Laurence Morel
Laurence Morel The University of Texas Health Science Center at San Antonio
Jennifer A. Kelly
Jennifer A. Kelly Oklahoma Medical Research Foundation
Patrick M. Gaffney
Patrick M. Gaffney Oklahoma Medical Research Foundation
Marta E. Alarcón-Riquelme
Marta E. Alarcón-Riquelme University of Granada
Swapan K. Nath
Swapan K. Nath Oklahoma Medical Research Foundation

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