World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
85
Citations
30697
World Ranking
864
National Ranking
398

Genetics

D-Index
85
Citations
30477
World Ranking
1299
National Ranking
617

Medicine

D-Index
84
Citations
30032
World Ranking
14970
National Ranking
7566

Overview

Patrick M. Gaffney is affiliated with the Oklahoma Medical Research Foundation in the United States. Their research spans multiple disciplines including Medicine, Biochemistry, Genetics and Molecular Biology, and Immunology and Microbiology. Their work extensively covers subfields such as Immunology, Molecular Biology, Rheumatology, Genetics, and Cancer Research.

Their research primarily focuses on topics including T-cell and B-cell Immunology, Systemic Lupus Erythematosus Research, Salivary Gland Disorders and Functions, Cancer-related molecular mechanisms, Immune Cell Function and Interaction, RNA modifications and cancer, as well as Diabetes and associated disorders.

Frequent co-authors who have collaborated with Patrick M. Gaffney include:

  • Jennifer A. Kelly
  • Kandice L. Tessneer
  • A. M. Stolarczyk
  • Joel M. Guthridge
  • Marie Wahren-Herlenius

Gaffney's work is published in a range of scientific venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Annals of the Rheumatic Diseases
  • Nature Communications
  • Nature Genetics
  • Frontiers in Genetics

Among recent publications, Patrick M. Gaffney has contributed to studies such as:

  • Genome-wide association study identifies Sjögren's risk loci with functional implications in immune and glandular cells, 2022, Nature Communications
  • Mutations in Spliceosomal Genes PPIL1 and PRP17 Cause Neurodegenerative Pontocerebellar Hypoplasia with Microcephaly, 2020, Neuron
  • Chromatin Looping Links Target Genes with Genetic Risk Loci for Dermatological Traits, 2021, Journal of Investigative Dermatology
  • Mapping DNA interaction landscapes in psoriasis susceptibility loci highlights KLF4 as a target gene in 9q31, 2020, BMC Biology
  • Genetic mapping across autoimmune diseases reveals shared associations and mechanisms, 2024, Nature Genetics

Best Publications

  • Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus

    Emily C. Baechler;Franak M. Batliwalla;George Karypis;Patrick M. Gaffney

  • The oyster genome reveals stress adaptation and complexity of shell formation

    Guofan Zhang;Xiaodong Fang;Ximing Guo;Li Li

  • Human polymorphism at microRNAs and microRNA target sites.

    Liuqing Yang;Chunru Lin;Chunyu Jin;Joy C. Yang

  • Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.

    John B. Harley;John B. Harley;John B. Harley;Marta E. Alarcón-Riquelme;Lindsey A. Criswell;Chaim O. Jacob

  • Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE.

    Chieko Kyogoku;Carl D. Langefeld;Ward A. Ortmann;Annette Lee

  • Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus.

    Robert R Graham;Chris Cotsapas;Chris Cotsapas;Leela Davies;Rachel Hackett

  • Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus.

    Robert R. Graham;Chieko Kyogoku;Snaevar Sigurdsson;Irina A. Vlasova

  • Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjogren's syndrome.

    Christopher J. Lessard;Christopher J. Lessard;He Li;He Li;Indra Adrianto;John A. Ice

  • Subsistence strategies in traditional societies distinguish gut microbiomes

    Alexandra J. Obregon-Tito;Raul Y. Tito;Jessica Metcalf;Krithivasan Sankaranarayanan

  • Identification of a Gene Expression Signature Associated with Recurrent Disease in Squamous Cell Carcinoma of the Head and Neck

    Matthew A. Ginos;Grier P. Page;Bryan S. Michalowicz;Ketan J. Patel

  • Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis

    Anne Hinks;Anne Hinks;Joanna E. Cobb;Joanna E. Cobb;Miranda C. Marion;Sampath Prahalad

  • A genome-wide search for susceptibility genes in human systemic lupus erythematosus sib-pair families

    Patrick M. Gaffney;Grainne M. Kearns;Grainne M. Kearns;Katherine B. Shark;Ward A. Ortmann

  • Transancestral mapping and genetic load in systemic lupus erythematosus

    Carl D. Langefeld;Hannah C. Ainsworth;Deborah S. Cunninghame Graham;Jennifer A. Kelly

  • Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort

    B. Namjou;P. H. Kothari;J. A. Kelly;S. B. Glenn

  • Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus

    David L. Morris;Yujun Sheng;Yujun Sheng;Yan Zhang;Yong Fei Wang

  • Peripheral blood gene expression profiling in Sjögren's syndrome.

    Eshrat S. Emamian;Joanlise M. Leon;Joanlise M. Leon;Christopher J. Lessard;Christopher J. Lessard;Martha Grandits

  • Genetic heterozygosity and growth rate in Mytilus edulis

    R. K. Koehn;P. M. Gaffney

  • Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus

    Indra Adrianto;Feng Wen;Amanda Templeton;Graham B. Wiley

  • Periostin promotes invasion and anchorage-independent growth in the metastatic process of head and neck cancer.

    Yasusei Kudo;Ikuko Ogawa;Shojiro Kitajima;Masae Kitagawa

  • Genome Screening in Human Systemic Lupus Erythematosus: Results from a Second Minnesota Cohort and Combined Analyses of 187 Sib-Pair Families

    Patrick M. Gaffney;Ward A. Ortmann;Scott A. Selby;Katherine B. Shark

Frequent Co-Authors

John B. Harley
John B. Harley United States Department of Veterans Affairs
Judith A. James
Judith A. James Oklahoma Medical Research Foundation
Marta E. Alarcón-Riquelme
Marta E. Alarcón-Riquelme University of Granada
Kenneth M. Kaufman
Kenneth M. Kaufman Cincinnati Children's Hospital Medical Center
Jennifer A. Kelly
Jennifer A. Kelly Oklahoma Medical Research Foundation
Kathy L. Moser
Kathy L. Moser Oklahoma Medical Research Foundation
Timothy J. Vyse
Timothy J. Vyse King's College London
Carl D. Langefeld
Carl D. Langefeld Wake Forest University
R. Hal Scofield
R. Hal Scofield University of Oklahoma Health Sciences Center
Robert P. Kimberly
Robert P. Kimberly University of Alabama at Birmingham

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