Patrick M. Gaffney focuses on Immunology, Genetics, Lupus erythematosus, Haplotype and Autoimmune disease. His studies in Immunology integrate themes in fields like Genome-wide association study, Genetic association, Genotype, Single-nucleotide polymorphism and Disease. His study in Human leukocyte antigen, Locus, Allele, Genetic linkage and Linkage disequilibrium are all subfields of Genetics.
Patrick M. Gaffney has included themes like Gene and FCGR2A in his Human leukocyte antigen study. Patrick M. Gaffney combines subjects such as Immune tolerance, B cell, Connective tissue disease, Protein kinase C and breakpoint cluster region with his study of Lupus erythematosus. The concepts of his Autoimmune disease study are interwoven with issues in IRF5, Pathogenesis, Gene expression profiling, Systemic disease and Anti-SSA/Ro autoantibodies.
Patrick M. Gaffney mainly investigates Immunology, Genetics, Single-nucleotide polymorphism, Haplotype and Allele. His Immunology study combines topics in areas such as Genome-wide association study and Genetic association. In his work, Molecular biology is strongly intertwined with Systemic lupus erythematosus, which is a subfield of Genetics.
His study in Single-nucleotide polymorphism is interdisciplinary in nature, drawing from both Odds ratio, Case-control study, Allele frequency and Genetic variation. As part of his studies on Haplotype, Patrick M. Gaffney often connects relevant areas like IRF5. His work carried out in the field of Allele brings together such families of science as Major histocompatibility complex, Genotype and Candidate gene.
His primary scientific interests are in Immunology, Genetics, Gene, Genome-wide association study and Chromatin. Patrick M. Gaffney has included themes like Single-nucleotide polymorphism and Disease in his Immunology study. His Single-nucleotide polymorphism research includes elements of Internal medicine and Allele, Haplotype.
His Genetics study frequently links to other fields, such as Evolutionary biology. His Gene study integrates concerns from other disciplines, such as Computational biology and Effector. His Genome-wide association study research is multidisciplinary, relying on both Expression quantitative trait loci, Human leukocyte antigen, Genetic association and Locus.
Patrick M. Gaffney mainly focuses on Genetics, Immunology, Genome-wide association study, Lupus erythematosus and Human leukocyte antigen. Immunology is closely attributed to Cancer research in his work. Within one scientific family, Patrick M. Gaffney focuses on topics pertaining to Genetic association under Genome-wide association study, and may sometimes address concerns connected to Genotyping, SNP array, Chromosome 12 and Meta-analysis.
His Lupus erythematosus research focuses on subjects like Polymorphism, which are linked to Vitamin D and neurology and Minor allele frequency. His studies link Haplotype with Human leukocyte antigen. Patrick M. Gaffney usually deals with Haplotype and limits it to topics linked to Major histocompatibility complex and Genetic variation, Single-nucleotide polymorphism and Allele.
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Human polymorphism at microRNAs and microRNA target sites.
Liuqing Yang;Chunru Lin;Chunyu Jin;Joy C. Yang.
Frontiers in Genetics (2013)
Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus
Emily C. Baechler;Franak M. Batliwalla;George Karypis;Patrick M. Gaffney.
Proceedings of the National Academy of Sciences of the United States of America (2003)
The oyster genome reveals stress adaptation and complexity of shell formation
Guofan Zhang;Xiaodong Fang;Ximing Guo;Li Li.
Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.
John B. Harley;John B. Harley;John B. Harley;Marta E. Alarcón-Riquelme;Lindsey A. Criswell;Chaim O. Jacob.
Nature Genetics (2008)
Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE.
Chieko Kyogoku;Carl D. Langefeld;Ward A. Ortmann;Annette Lee.
American Journal of Human Genetics (2004)
Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus.
Robert R Graham;Chris Cotsapas;Chris Cotsapas;Leela Davies;Rachel Hackett.
Nature Genetics (2008)
Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus.
Robert R. Graham;Chieko Kyogoku;Snaevar Sigurdsson;Irina A. Vlasova.
Proceedings of the National Academy of Sciences of the United States of America (2007)
A Genome-Wide Search for Susceptibility Genes in Human Systemic Lupus Erythematosus Sib-Pair Families
Patrick M. Gaffney;Grainne M. Kearns;Grainne M. Kearns;Katherine B. Shark;Ward A. Ortmann.
Proceedings of the National Academy of Sciences of the United States of America (1998)
Identification of a Gene Expression Signature Associated with Recurrent Disease in Squamous Cell Carcinoma of the Head and Neck
Matthew A. Ginos;Grier P. Page;Bryan S. Michalowicz;Ketan J. Patel.
Cancer Research (2004)
Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjogren's syndrome.
Christopher J. Lessard;Christopher J. Lessard;He Li;He Li;Indra Adrianto;John A. Ice.
Nature Genetics (2013)
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