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Biology and Biochemistry

D-Index
53
Citations
18709
World Ranking
15910
National Ranking
1251

Overview

Hanieh Yaghootkar is affiliated with the University of Exeter in the United Kingdom, with a research focus primarily on genetics within the fields of medicine and biochemistry, genetics, and molecular biology. Their work spans a variety of specialized subfields, including genetics, epidemiology, molecular biology, endocrinology, diabetes and metabolism, and cardiology and cardiovascular medicine.

The researcher has contributed to topics such as genetic associations and epidemiology, liver disease diagnosis and treatment, birth, development, and health, cardiovascular disease and adiposity, adipose tissue and metabolism, pancreatic function and diabetes, and obesity, physical activity, and diet.

Among their notable recent publications are:

  • Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression (2021, Nature Genetics)
  • Genome-wide and Mendelian randomisation studies of liver MRI yield insights into the pathogenesis of steatohepatitis (2020, Journal of Hepatology)
  • Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour (2021, Nature Human Behaviour)
  • rs641738C>T near MBOAT7 is associated with liver fat, ALT and fibrosis in NAFLD: A meta-analysis (2020, Journal of Hepatology)
  • Genetic Evidence for Different Adiposity Phenotypes and Their Opposing Influences on Ectopic Fat and Risk of Cardiometabolic Disease (2021, Diabetes)

Hanieh Yaghootkar frequently publishes in venues such as the Journal of Hepatology, Diabetes, Diabetic Medicine, UNC Libraries, and bioRxiv (Cold Spring Harbor Laboratory).

The scientist regularly collaborates with other researchers, including Timothy M. Frayling, E. Louise Thomas, Jimmy D. Bell, Jessica Tyrrell, and Andrew R. Wood.

Best Publications

  • Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression

    Urmo Võsa;Annique Claringbould;Annique Claringbould;Harm-Jan Westra;Marc Jan Bonder

  • Systematic identification of trans eQTLs as putative drivers of known disease associations

    Harm-Jan Westra;Marjolein J Peters;Tõnu Esko;Hanieh Yaghootkar

  • A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.

    Alisa K. Manning;Alisa K. Manning;Alisa K. Manning;Robert A. Scott;Jonna L. Grimsby

  • Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry

    Sara L Pulit;Sara L Pulit;Sara L Pulit;Charli Stoneman;Andrew P Morris;Andrew P Morris;Andrew R Wood

  • Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

    Richard Karlsson Linnér;Richard Karlsson Linnér;Pietro Biroli;Edward Kong;S. Fleur W. Meddens;S. Fleur W. Meddens

  • The transcriptional landscape of age in human peripheral blood

    Marjolein J. Peters;Roby Joehanes;Luke C. Pilling;Claudia Schurmann;Claudia Schurmann

  • Genome-wide association analyses of chronotype in 697,828 individuals provides insights into circadian rhythms.

    Samuel E. Jones;Jacqueline M. Lane;Jacqueline M. Lane;Andrew R. Wood;Vincent T. van Hees

  • Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

    Nicole M Warrington;Robin N Beaumont;Momoko Horikoshi;Felix R Day

  • Exome-wide association study of plasma lipids in > 300,000 individuals

    Dajiang J Liu;Gina M Peloso;Gina M Peloso;Haojie Yu;Adam S Butterworth;Adam S Butterworth

  • Genome-wide associations for birth weight and correlations with adult disease

    Momoko Horikoshi;Robin N. Beaumont;Felix R. Day;Nicole M. Warrington;Nicole M. Warrington

  • Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance

    Luca A Lotta;Pawan Gulati;Felix R Day;Felicity Payne

  • Unraveling the polygenic architecture of complex traits using blood eQTL metaanalysis

    Võsa U;Claringbould A;Westra H;Bonder Mj

  • Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

    Valérie Turcot;Yingchang Lu;Yingchang Lu;Heather M Highland;Heather M Highland;Claudia Schurmann

  • Genome-Wide Association Analyses in 128,266 Individuals Identifies New Morningness and Sleep Duration Loci.

    Samuel E. Jones;Jessica Tyrrell;Andrew R. Wood;Robin N. Beaumont

  • Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

    Anubha Mahajan;Jennifer Wessel;Sara M. Willems;Wei Zhao

  • Height, body mass index, and socioeconomic status: mendelian randomisation study in UK Biobank

    Jessica Tyrrell;Jessica Tyrrell;Samuel E Jones;Robin Beaumont;Christina M Astley;Christina M Astley

  • Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood

    Ting Qi;Yang Wu;Jian Zeng;Futao Zhang

  • New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism.

    Momoko Horikoshi;Hanieh Yaghootkar;Dennis O. Mook-Kanamori;Dennis O. Mook-Kanamori;Ulla Sovio;Ulla Sovio

  • Genome-wide association analyses of chronotype in 697, 828 individuals provides insights into circadian rhythms

    Jones Se;Lane Jm;Wood Ar;van Hees Vt

  • New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism

    Momoko Horikoshi;Hanieh Yaghootkar;Dennis O. Mook-Kanamori;Ulla Sovio

Frequent Co-Authors

Timothy M. Frayling
Timothy M. Frayling University of Geneva
Andrew R. Wood
Andrew R. Wood University of Exeter
Zoltán Kutalik
Zoltán Kutalik University of Lausanne
Andrew P. Morris
Andrew P. Morris University of Liverpool
Cecilia M. Lindgren
Cecilia M. Lindgren University of Oxford
Claudia Langenberg
Claudia Langenberg Queen Mary University of London
Markus Perola
Markus Perola Finnish Institute for Health and Welfare
Nicholas J. Wareham
Nicholas J. Wareham University of Cambridge
Andrew T. Hattersley
Andrew T. Hattersley University of Exeter

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