D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics and Molecular Biology D-index 103 Citations 72,219 236 World Ranking 378 National Ranking 46
Medicine D-index 108 Citations 65,359 267 World Ranking 2603 National Ranking 260

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Internal medicine
  • Genetics

His scientific interests lie mostly in Genetics, Genome-wide association study, Single-nucleotide polymorphism, Internal medicine and Genetic association. His studies deal with areas such as Body mass index and Case-control study as well as Genetics. The various areas that Timothy M. Frayling examines in his Genome-wide association study study include SNP, Quantitative trait locus, Genetic architecture, Allele and Glucose homeostasis.

His Single-nucleotide polymorphism research incorporates elements of Mendelian randomization, Polymorphism, Allele frequency, Meta-analysis and Heritability. His Internal medicine research integrates issues from Endocrinology and Type 2 diabetes. His Type 2 diabetes research incorporates themes from CDKAL1 and TCF7L2.

His most cited work include:

  • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls (7922 citations)
  • A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity (3415 citations)
  • Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index (2348 citations)

What are the main themes of his work throughout his whole career to date?

Timothy M. Frayling mainly focuses on Genetics, Genome-wide association study, Type 2 diabetes, Internal medicine and Endocrinology. His study in Single-nucleotide polymorphism, Genetic association, Allele, Gene and Locus falls within the category of Genetics. The Single-nucleotide polymorphism study combines topics in areas such as Genetic variation and Allele frequency.

In Genome-wide association study, he works on issues like Body mass index, which are connected to FTO gene and Meta-analysis. His study in Type 2 diabetes is interdisciplinary in nature, drawing from both Birth weight, TCF7L2 and Case-control study. His Internal medicine research includes themes of Mendelian randomization and Polymorphism.

He most often published in these fields:

  • Genetics (47.99%)
  • Genome-wide association study (34.12%)
  • Type 2 diabetes (33.94%)

What were the highlights of his more recent work (between 2016-2021)?

  • Genome-wide association study (34.12%)
  • Internal medicine (32.12%)
  • Genetics (47.99%)

In recent papers he was focusing on the following fields of study:

Timothy M. Frayling focuses on Genome-wide association study, Internal medicine, Genetics, Mendelian randomization and Type 2 diabetes. The subject of his Genome-wide association study research is within the realm of Single-nucleotide polymorphism. The study incorporates disciplines such as Endocrinology, Oncology and Insomnia in addition to Internal medicine.

While the research belongs to areas of Genetics, Timothy M. Frayling spends his time largely on the problem of Meta-analysis, intersecting his research to questions surrounding Genome. His studies in Mendelian randomization integrate themes in fields like Mendelian Randomization Analysis, Disease and Risk factor. The Type 2 diabetes study which covers Heart disease that intersects with Apolipoprotein B and First-degree relatives.

Between 2016 and 2021, his most popular works were:

  • Meta-analysis of genome-wide association studies for height and body mass index in ∼700000 individuals of European ancestry (539 citations)
  • Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps. (503 citations)
  • An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans (374 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Internal medicine
  • Genetics

Timothy M. Frayling spends much of his time researching Genome-wide association study, Genetics, Body mass index, Genetic association and Internal medicine. Genome-wide association study is the subject of his research, which falls under Single-nucleotide polymorphism. His research in Single-nucleotide polymorphism intersects with topics in Waist–hip ratio, Exome and Heritability.

The study of Genetics is intertwined with the study of Coding in a number of ways. His Body mass index research is multidisciplinary, incorporating perspectives in FTO gene, Obesity and Genetic predisposition. Timothy M. Frayling interconnects Endocrinology and Insomnia in the investigation of issues within Internal medicine.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

Paul R. Burton;David G. Clayton;Lon R. Cardon;Nick Craddock.
Nature (2007)

7828 Citations

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

Timothy M. Frayling;Nicholas J. Timpson;Michael N. Weedon;Eleftheria Zeggini;Eleftheria Zeggini;Eleftheria Zeggini.
Science (2007)

5577 Citations

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

Elizabeth K. Speliotes;Elizabeth K. Speliotes;Cristen J. Willer;Sonja I. Berndt;Keri L. Monda.
Nature Genetics (2010)

2864 Citations

Replication of Genome-Wide Association Signals in UK Samples Reveals Risk Loci for Type 2 Diabetes

Eleftheria Zeggini;Michael N Weedon;Cecilia M Lindgren;Timothy M Frayling.
Science (2007)

2453 Citations

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

E Zeggini;L J Scott;R Saxena;B F Voight.
Nature Genetics (2008)

2051 Citations

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

Josée Dupuis;Josée Dupuis;Claudia Langenberg;Inga Prokopenko;Richa Saxena;Richa Saxena.
Nature Genetics (2010)

2013 Citations

Hundreds of variants clustered in genomic loci and biological pathways affect human height

Hana Lango Allen;Karol Estrada;Guillaume Lettre;Sonja I. Berndt.
Nature (2010)

1934 Citations

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

Benjamin F. Voight;Benjamin F. Voight;Laura J. Scott;Valgerdur Steinthorsdottir;Andrew P. Morris.
Nature Genetics (2010)

1829 Citations

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

Georg B. Ehret;Georg B. Ehret;Georg B. Ehret;Patricia B. Munroe;Kenneth M. Rice;Murielle Bochud.
Nature (2011)

1802 Citations

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

Cristen J. Willer;Elizabeth K. Speliotes;Elizabeth K. Speliotes;Ruth J. F. Loos;Shengxu Li.
Nature Genetics (2009)

1789 Citations

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