World's Best Scientists 2026 revealed!
Timothy M. Frayling

Timothy M. Frayling

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Genetics
Switzerland
2026
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Medicine
Switzerland
2026

D-Index & Metrics

Best Scientists

D-Index
165
Citations
148456
World Ranking
1019
National Ranking
12

Genetics

D-Index
164
Citations
150915
World Ranking
79
National Ranking
1

Medicine

D-Index
165
Citations
152378
World Ranking
613
National Ranking
7

Research.com Recognitions

  • 2026 - Research.com Genetics in Switzerland Leader Award
  • 2026 - Research.com Medicine in Switzerland Leader Award
  • 2025 - Research.com Genetics in Switzerland Leader Award
  • 2025 - Research.com Medicine in Switzerland Leader Award
  • 2024 - Research.com Genetics in United Kingdom Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in United Kingdom Leader Award
  • 2023 - Research.com Genetics in United Kingdom Leader Award

Overview

Timothy M. Frayling is affiliated with the University of Geneva in Switzerland and has made substantial contributions in the fields of Biochemistry, Genetics, and Molecular Biology, in addition to Medicine. Their work spans several subfields including Genetics, Molecular Biology, Public Health, Environmental and Occupational Health, Endocrinology, Diabetes and Metabolism, and Epidemiology.

The scientist's research primarily addresses topics such as Genetic Associations and Epidemiology, Obesity, Physical Activity, Diet, Birth, Development, and Health, Epigenetics and DNA Methylation, Diabetes, Cardiovascular Risks, and Lipoproteins, Genomics and Rare Diseases, and Sleep and related disorders.

Recent significant publications include:

  • Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression, 2021, Nature Genetics
  • Using human genetics to understand the disease impacts of testosterone in men and women, 2020, Nature Medicine
  • Genetic insights into biological mechanisms governing human ovarian ageing, 2021, Nature
  • Phantasia-The psychological significance of lifelong visual imagery vividness extremes, 2020, Cortex
  • Genetic predictors of participation in optional components of UK Biobank, 2021, Nature Communications

Frequent coauthors in their publications include:

  • Andrew R. Wood
  • Robin N. Beaumont
  • Jessica Tyrrell
  • Michael N. Weedon
  • George Davey Smith

Timothy M. Frayling has published extensively in several venues, with the most frequent being:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Diabetes
  • UNC Libraries
  • Nature Communications
  • Human Molecular Genetics

Best Publications

  • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

    Paul R. Burton;David G. Clayton;Lon R. Cardon;Nick Craddock

  • A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

    Timothy M. Frayling;Nicholas J. Timpson;Michael N. Weedon;Eleftheria Zeggini;Eleftheria Zeggini;Eleftheria Zeggini

  • Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

    Elizabeth K. Speliotes;Elizabeth K. Speliotes;Cristen J. Willer;Sonja I. Berndt;Keri L. Monda

  • A reference panel of 64,976 haplotypes for genotype imputation

    Shane McCarthy;Sayantan Das;Warren Kretzschmar;Olivier Delaneau

  • Replication of Genome-Wide Association Signals in UK Samples Reveals Risk Loci for Type 2 Diabetes

    Eleftheria Zeggini;Michael N. Weedon;Cecilia M. Lindgren;Timothy M. Frayling

  • New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

    Josée Dupuis;Josée Dupuis;Claudia Langenberg;Inga Prokopenko;Richa Saxena;Richa Saxena

  • Hundreds of variants clustered in genomic loci and biological pathways affect human height

    Hana Lango Allen;Karol Estrada;Guillaume Lettre;Sonja I. Berndt

  • Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

    Georg B. Ehret;Georg B. Ehret;Georg B. Ehret;Patricia B. Munroe;Kenneth M. Rice;Murielle Bochud

  • Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

    E Zeggini;L J Scott;R Saxena;B F Voight

  • Defining the role of common variation in the genomic and biological architecture of adult human height

    Andrew R. Wood;Tonu Esko;Jian Yang;Sailaja Vedantam

  • New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk (vol 42, pg 105, 2010)

    J Dupuis;C Langenberg;I Prokopenko;R Saxena

  • Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

    Benjamin F. Voight;Benjamin F. Voight;Laura J. Scott;Valgerdur Steinthorsdottir;Andrew P. Morris

  • Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

    Andrew P Morris;Benjamin F Voight;Benjamin F Voight;Tanya M Teslovich;Teresa Ferreira

  • Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

    Cristen J. Willer;Elizabeth K. Speliotes;Elizabeth K. Speliotes;Ruth J. F. Loos;Shengxu Li

  • Meta-analysis of genome-wide association studies for height and body mass index in ∼700000 individuals of European ancestry

    Loic Yengo;Julia Sidorenko;Julia Sidorenko;Kathryn E Kemper;Zhili Zheng

  • Systematic identification of trans eQTLs as putative drivers of known disease associations

    Harm-Jan Westra;Marjolein J Peters;Tõnu Esko;Hanieh Yaghootkar

  • A genome-wide association search for type 2 diabetes genes in African Americans.

    N D Palmer;C W McDonough;P J Hicks;B H Roh

  • Genetic studies of body mass index yield new insights for obesity biology

    Adam E. Locke;Bratati Kahali;Sonja I. Berndt;Anne E. Justice

  • Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk (Nature Genetics (2010) 42 (105-116))

    Josée Dupuis;Claudia Langenberg;Inga Prokopenko;Richa Saxena

  • Hundreds of variants clustered in genomic loci and biological pathways affect human height

    H. Lango Allen;K. Estrada;G. Lettre;S. I. Berndt

Frequent Co-Authors

Andrew T. Hattersley
Andrew T. Hattersley University of Exeter
Andrew R. Wood
Andrew R. Wood University of Exeter
Cecilia M. Lindgren
Cecilia M. Lindgren University of Oxford
Michael N. Weedon
Michael N. Weedon University of Exeter
Nicholas J. Wareham
Nicholas J. Wareham University of Cambridge
Andrew P. Morris
Andrew P. Morris University of Liverpool
Joel N. Hirschhorn
Joel N. Hirschhorn Boston Children's Hospital
Inga Prokopenko
Inga Prokopenko University of Surrey
Erik Ingelsson
Erik Ingelsson Stanford University

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