His scientific interests lie mostly in Genetics, Genome-wide association study, Single-nucleotide polymorphism, Internal medicine and Genetic association. His studies deal with areas such as Body mass index and Case-control study as well as Genetics. The various areas that Timothy M. Frayling examines in his Genome-wide association study study include SNP, Quantitative trait locus, Genetic architecture, Allele and Glucose homeostasis.
His Single-nucleotide polymorphism research incorporates elements of Mendelian randomization, Polymorphism, Allele frequency, Meta-analysis and Heritability. His Internal medicine research integrates issues from Endocrinology and Type 2 diabetes. His Type 2 diabetes research incorporates themes from CDKAL1 and TCF7L2.
Timothy M. Frayling mainly focuses on Genetics, Genome-wide association study, Type 2 diabetes, Internal medicine and Endocrinology. His study in Single-nucleotide polymorphism, Genetic association, Allele, Gene and Locus falls within the category of Genetics. The Single-nucleotide polymorphism study combines topics in areas such as Genetic variation and Allele frequency.
In Genome-wide association study, he works on issues like Body mass index, which are connected to FTO gene and Meta-analysis. His study in Type 2 diabetes is interdisciplinary in nature, drawing from both Birth weight, TCF7L2 and Case-control study. His Internal medicine research includes themes of Mendelian randomization and Polymorphism.
Timothy M. Frayling focuses on Genome-wide association study, Internal medicine, Genetics, Mendelian randomization and Type 2 diabetes. The subject of his Genome-wide association study research is within the realm of Single-nucleotide polymorphism. The study incorporates disciplines such as Endocrinology, Oncology and Insomnia in addition to Internal medicine.
While the research belongs to areas of Genetics, Timothy M. Frayling spends his time largely on the problem of Meta-analysis, intersecting his research to questions surrounding Genome. His studies in Mendelian randomization integrate themes in fields like Mendelian Randomization Analysis, Disease and Risk factor. The Type 2 diabetes study which covers Heart disease that intersects with Apolipoprotein B and First-degree relatives.
Timothy M. Frayling spends much of his time researching Genome-wide association study, Genetics, Body mass index, Genetic association and Internal medicine. Genome-wide association study is the subject of his research, which falls under Single-nucleotide polymorphism. His research in Single-nucleotide polymorphism intersects with topics in Waist–hip ratio, Exome and Heritability.
The study of Genetics is intertwined with the study of Coding in a number of ways. His Body mass index research is multidisciplinary, incorporating perspectives in FTO gene, Obesity and Genetic predisposition. Timothy M. Frayling interconnects Endocrinology and Insomnia in the investigation of issues within Internal medicine.
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Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
Paul R. Burton;David G. Clayton;Lon R. Cardon;Nick Craddock.
Nature (2007)
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
Timothy M. Frayling;Nicholas J. Timpson;Michael N. Weedon;Eleftheria Zeggini;Eleftheria Zeggini;Eleftheria Zeggini.
Science (2007)
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
Elizabeth K. Speliotes;Elizabeth K. Speliotes;Cristen J. Willer;Sonja I. Berndt;Keri L. Monda.
Nature Genetics (2010)
Replication of Genome-Wide Association Signals in UK Samples Reveals Risk Loci for Type 2 Diabetes
Eleftheria Zeggini;Michael N Weedon;Cecilia M Lindgren;Timothy M Frayling.
Science (2007)
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes
E Zeggini;L J Scott;R Saxena;B F Voight.
Nature Genetics (2008)
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
Josée Dupuis;Josée Dupuis;Claudia Langenberg;Inga Prokopenko;Richa Saxena;Richa Saxena.
Nature Genetics (2010)
Hundreds of variants clustered in genomic loci and biological pathways affect human height
Hana Lango Allen;Karol Estrada;Guillaume Lettre;Sonja I. Berndt.
Nature (2010)
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
Benjamin F. Voight;Benjamin F. Voight;Laura J. Scott;Valgerdur Steinthorsdottir;Andrew P. Morris.
Nature Genetics (2010)
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk
Georg B. Ehret;Georg B. Ehret;Georg B. Ehret;Patricia B. Munroe;Kenneth M. Rice;Murielle Bochud.
Nature (2011)
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation
Cristen J. Willer;Elizabeth K. Speliotes;Elizabeth K. Speliotes;Ruth J. F. Loos;Shengxu Li.
Nature Genetics (2009)
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