Thomas Wirth

Overview

Best Publications

• NF-κB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression

  Margit A. Huber;Ninel Azoitei;Bernd Baumann;Stefan Grünert

  1207
  Citations

• NF-kappaB is activated and promotes cell death in focal cerebral ischemia.

  Armin Schneider;Ana Martin-Villalba;Falk Weih;Johannes Vogel

  860
  Citations

• A lymphoid-specific protein binding to the octamer motif of immunoglobulin genes.

  Louis M. Staudt;Harinder Singh;Ranjan Sen;Thomas Wirth

  746
  Citations

• Hodgkin and Reed-Sternberg cells represent an expansion of a single clone originating from a germinal center B-cell with functional immunoglobulin gene rearrangements but defective immunoglobulin transcription

  Theresa Marafioti;Michael Hummel;Michael Hummel;Hans-Dieter Foss;Hans-Dieter Foss;Helmut Laumen;Helmut Laumen

  665
  Citations

• History of gene therapy

  Thomas Wirth;Nigel Parker;Seppo Ylä-Herttuala

  649
  Citations

• MYC stimulates EZH2 expression by repression of its negative regulator miR-26a.

  Sandrine Sander;Lars Bullinger;Kay Klapproth;Katja Fiedler

  472
  Citations

• An octamer oligonucleotide upstream of a TATA motif is sufficient for lymphoid-specific promoter activity.

  Thomas Wirth;Louis Staudt;David Baltimore

  434
  Citations

• Suppression of NF-κB activity by sulfasalazine is mediated by direct inhibition of IκB kinases α and β

  Christoph K. Weber;Susanne Liptay;Thomas Wirth;Guido Adler

  392
  Citations

• Bruton's Tyrosine Kinase Is a Toll/Interleukin-1 Receptor Domain-binding Protein That Participates in Nuclear Factor κB Activation by Toll-like Receptor 4

  Caroline A. Jefferies;Sarah Doyle;Cornelia Brunner;Aisling Dunne

  391
  Citations

• Down-regulation of BOB.1/OBF.1 and Oct2 in classical Hodgkin disease but not in lymphocyte predominant Hodgkin disease correlates with immunoglobulin transcription.

  Harald Stein;Theresa Marafioti;Hans-Dieter Foss;Helmut Laumen

  354
  Citations

• NF-κB controls the global pro-inflammatory response in endothelial cells: evidence for the regulation of a pro-atherogenic program

  Sybille Kempe;Hans Kestler;Andrea Lasar;Thomas Wirth

  350
  Citations

• Inhibition of Nuclear Factor κB Activation Attenuates Apoptosis Resistance in Lymphoid Cells

  I. Jeremias;C. Kupatt;B. Baumann;I. Herr

  325
  Citations

• TNFα promotes osteogenic differentiation of human mesenchymal stem cells by triggering the NF-κB signaling pathway

  Katrin Hess;Alexey Ushmorov;Jörg Fiedler;Rolf E. Brenner

  316
  Citations

• High mobility group protein 2 functionally interacts with the POU domains of octamer transcription factors.

  S Zwilling;H König;T Wirth

  315
  Citations

• Sulforaphane targets pancreatic tumour-initiating cells by NF-κB-induced antiapoptotic signalling

  Georgios Kallifatidis;Vanessa Rausch;Bernd Baumann;Anja Apel

  315
  Citations

• IKK mediates ischemia-induced neuronal death.

  Oliver Herrmann;Bernd Baumann;Rossana de Lorenzi;Sajjad Muhammad

  314
  Citations

• A role for nuclear NF-kappaB in B-cell-specific demethylation of the Igkappa locus.

  Andrei Kirillov;Barbara Kistler;Raul Mostoslavsky;Howard Cedar

  301
  Citations

• NF-κB promotes epithelial–mesenchymal transition, migration and invasion of pancreatic carcinoma cells

  Harald J. Maier;Uta Schmidt-Straßburger;Margit A. Huber;Margit A. Huber;Eva M. Wiedemann

  276
  Citations

• Activation of NF-κB via the IκB Kinase Complex Is Both Essential and Sufficient for Proinflammatory Gene Expression in Primary Endothelial Cells

  Andrea Denk;Matthias Goebeler;Sybille Schmid;Ingolf Berberich

  269
  Citations

• GSE12278: MYC stimulates EZH2 expression by repression of its negative regulator miR-26a.

  Lars Bullinger;Sandrine Sander;Kay Klapproth;Katja Fiedler

  0
  Citations