His primary scientific interests are in Postsynaptic density, Neuroscience, Cell biology, SHANK2 and Postsynaptic potential. His work deals with themes such as Dendritic spine, Synapse, Cytoskeleton and Synaptogenesis, which intersect with Postsynaptic density. His research in Neuroscience intersects with topics in Synaptic plasticity, Immunology, Neurotransmission and Presynaptic active zone.
His Cell biology research is multidisciplinary, incorporating perspectives in Calcium-activated potassium channel, Active zone, Synaptic vesicle and Actin cytoskeleton. The various areas that Tobias M. Boeckers examines in his SHANK2 study include Biophysics, Scaffold protein, PDZ domain, Autism and Cortactin. His study in Autism is interdisciplinary in nature, drawing from both Genetics and 22q13 deletion syndrome.
The scientist’s investigation covers issues in Cell biology, Neuroscience, Postsynaptic density, Postsynaptic potential and SHANK2. His Cell biology study integrates concerns from other disciplines, such as Glutamatergic, Actin cytoskeleton, Cytoskeleton and Induced pluripotent stem cell. The concepts of his Neuroscience study are interwoven with issues in Phenotype, Amyotrophic lateral sclerosis, Autism and Neurotransmission.
Tobias M. Boeckers has included themes like Dendritic spine, Synapse and Scaffold protein in his Postsynaptic density study. His Postsynaptic potential research includes themes of Active zone, Biophysics and Synaptogenesis. He combines subjects such as NMDA receptor and Long-term potentiation with his study of Synaptic plasticity.
Tobias M. Boeckers spends much of his time researching Neuroscience, Cell biology, Amyotrophic lateral sclerosis, Autism and Postsynaptic potential. His work in Forebrain, Postsynaptic density, Dendritic spine, Hippocampal formation and Central nervous system are all subfields of Neuroscience research. His Postsynaptic density study necessitates a more in-depth grasp of Neurotransmission.
His Cell biology research integrates issues from Glutamate receptor, TANK-binding kinase 1 and Voltage-dependent calcium channel. His Autism study combines topics from a wide range of disciplines, such as Synaptic plasticity, Phenotype, Haploinsufficiency, Knockout mouse and SHANK2. His biological study spans a wide range of topics, including Synapse, Myogenesis, Skeletal muscle and Acetylcholine receptor.
Tobias M. Boeckers spends much of his time researching Cell biology, Amyotrophic lateral sclerosis, Postsynaptic potential, Autism and HOMER1. His Cell biology research is mostly focused on the topic PI3K/AKT/mTOR pathway. His studies deal with areas such as Myogenesis, Skeletal muscle, Motor neuron, Neuromuscular junction and Acetylcholine receptor as well as Amyotrophic lateral sclerosis.
His Postsynaptic potential study combines topics in areas such as Neuroscience and ETS transcription factor family. His Autism research incorporates elements of Microbiome, Epithelium, Phenotype, Lipopolysaccharide and Ankyrin repeat. The study incorporates disciplines such as Mutation, Synapse, Induced pluripotent stem cell and Synaptogenesis in addition to HOMER1.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders.
Christelle M Durand;Catalina Betancur;Tobias M Boeckers;Juergen Bockmann.
Nature Genetics (2007)
Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia
Axel Freischmidt;Thomas Wieland;Benjamin Richter;Wolfgang Ruf.
Nature Neuroscience (2015)
Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2
Michael J. Schmeisser;Elodie Ey;Stephanie Wegener;Juergen Bockmann.
Genetic and Functional Analyses of SHANK2 Mutations Suggest a Multiple Hit Model of Autism Spectrum Disorders
Claire S. Leblond;Jutta Heinrich;Richard Delorme;Christian Proepper.
PLOS Genetics (2012)
Meta-analysis of SHANK Mutations in Autism Spectrum Disorders: A Gradient of Severity in Cognitive Impairments
Claire S. Leblond;Caroline Nava;Anne Polge;Julie Gauthier.
PLOS Genetics (2014)
ProSAP/Shank proteins - a family of higher order organizing molecules of the postsynaptic density with an emerging role in human neurological disease.
Tobias M. Boeckers;Jürgen Bockmann;Michael R. Kreutz;Eckart D. Gundelfinger.
Journal of Neurochemistry (2002)
An architectural framework that may lie at the core of the postsynaptic density.
Marisa K. Baron;Tobias M. Boeckers;Bianca Vaida;Salem Faham.
The postsynaptic density.
T. M. Boeckers.
Cell and Tissue Research (2006)
Proline-Rich Synapse-Associated Protein-1/Cortactin Binding Protein 1 (ProSAP1/CortBP1) Is a PDZ-Domain Protein Highly Enriched in the Postsynaptic Density
Tobias M. Boeckers;Michael R. Kreutz;Carsten Winter;Werner Zuschratter.
The Journal of Neuroscience (1999)
Functional inactivation of a fraction of excitatory synapses in mice deficient for the active zone protein bassoon.
Wilko D. Altrock;Susanne tom Dieck;Susanne tom Dieck;Maxim Sokolov;Alexander C. Meyer.
If you think any of the details on this page are incorrect, let us know.
We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below: