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Tobias M. Boeckers

Tobias M. Boeckers

D-Index & Metrics

Biology and Biochemistry

D-Index
83
Citations
23841
World Ranking
3516
National Ranking
267

Overview

Tobias M. Boeckers is affiliated with the University of Ulm in Germany and contributes extensively to research at the intersection of medicine, biochemistry, genetics, and neuroscience. Their work spans multiple subfields including neurology, molecular biology, genetics, cognitive neuroscience, and cellular and molecular neuroscience.

Their research topics cover a wide range of areas such as genetics and neurodevelopmental disorders, amyotrophic lateral sclerosis (ALS) research, autism spectrum disorder, neurogenetic and muscular disorders, neuroinflammation and neurodegeneration mechanisms, traumatic brain injury and neurovascular disturbances, as well as broader neuroscience and neuropharmacology research.

Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular Psychiatry
  • Nature Communications
  • Frontiers in Molecular Neuroscience
  • BMC Biology

Notable recent papers authored or co-authored by Tobias M. Boeckers are:

  • "IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition in vitro," 2021, Nature Communications
  • "Comparison of SHANK3 deficiency in animal models: phenotypes, treatment strategies, and translational implications," 2021, Journal of Neurodevelopmental Disorders
  • "Autism-associated SHANK3 mutations impair maturation of neuromuscular junctions and striated muscles," 2020, Science Translational Medicine
  • "Interleukin-13 and its receptor are synaptic proteins involved in plasticity and neuroprotection," 2023, Nature Communications
  • "Phelan-McDermid syndrome: a classification system after 30 years of experience," 2022, Orphanet Journal of Rare Diseases

Frequent collaborators in their research include:

  • Francesco Roselli
  • Albert C. Ludolph
  • Alberto Catanese
  • Florian olde Heuvel
  • Chiara Verpelli

Their publication record reflects a sustained contribution to the understanding of neurodevelopmental and neurodegenerative mechanisms, particularly focusing on genetic contributions to disease phenotypes and molecular pathways involved in neuroprotection and muscle development.

Best Publications

  • Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders.

    Christelle M Durand;Catalina Betancur;Tobias M Boeckers;Juergen Bockmann

  • Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia

    Axel Freischmidt;Thomas Wieland;Benjamin Richter;Wolfgang Ruf

  • Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2

    Michael J. Schmeisser;Elodie Ey;Stephanie Wegener;Juergen Bockmann

  • Meta-analysis of SHANK Mutations in Autism Spectrum Disorders: A Gradient of Severity in Cognitive Impairments

    Claire S. Leblond;Caroline Nava;Anne Polge;Julie Gauthier

  • Kainate-induced seizures alter protein composition and N-methyl-d-aspartate receptor function of rat forebrain postsynaptic densities

    U Wyneken;K.-H Smalla;K.-H Smalla;J.J Marengo;D Soto

  • Genetic and Functional Analyses of SHANK2 Mutations Suggest a Multiple Hit Model of Autism Spectrum Disorders

    Claire S. Leblond;Jutta Heinrich;Richard Delorme;Christian Proepper

  • ProSAP/Shank proteins - a family of higher order organizing molecules of the postsynaptic density with an emerging role in human neurological disease.

    Tobias M. Boeckers;Jürgen Bockmann;Michael R. Kreutz;Eckart D. Gundelfinger

  • An architectural framework that may lie at the core of the postsynaptic density.

    Marisa K. Baron;Tobias M. Boeckers;Tobias M. Boeckers;Tobias M. Boeckers;Bianca Vaida;Bianca Vaida;Bianca Vaida;Salem Faham;Salem Faham;Salem Faham

  • Proline-rich synapse-associated protein-1/cortactin binding protein 1 (ProSAP1/CortBP1) is a PDZ-domain protein highly enriched in the postsynaptic density.

    Tobias M. Boeckers;Michael R. Kreutz;Carsten Winter;Werner Zuschratter

  • Brevican-deficient mice display impaired hippocampal CA1 long-term potentiation but show no obvious deficits in learning and memory

    Cord Brakebusch;Constanze I. Seidenbecher;Fredrik Asztely;Uwe Rauch

  • The postsynaptic density.

    T. M. Boeckers

  • Functional inactivation of a fraction of excitatory synapses in mice deficient for the active zone protein bassoon.

    Wilko D. Altrock;Susanne tom Dieck;Susanne tom Dieck;Maxim Sokolov;Alexander C. Meyer

  • Proline-rich synapse-associated proteins ProSAP1 and ProSAP2 interact with synaptic proteins of the SAPAP/GKAP family.

    Tobias M. Boeckers;Carsten Winter;Karl-Heinz Smalla;Michael R. Kreutz

  • Concerted action of zinc and ProSAP/Shank in synaptogenesis and synapse maturation

    Andreas M Grabrucker;Andreas M Grabrucker;Mary J Knight;Christian Proepper;Juergen Bockmann

  • Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation

    Marcel Naumann;Arun Pal;Anand Goswami;Xenia Lojewski

  • Dysfunctional cerebellar Purkinje cells contribute to autism-like behaviour in Shank2-deficient mice.

    Saša Peter;Michiel M. Ten Brinke;Jeffrey Stedehouder;Claudia M. Reinelt

  • Postsynaptic ProSAP/Shank scaffolds in the cross-hair of synaptopathies.

    Andreas M. Grabrucker;Michael J. Schmeisser;Michael Schoen;Tobias M. Boeckers

  • Neurocan is dispensable for brain development

    Xiao-Hong Zhou;Cord Brakebusch;Henry Matthies;Toshitaka Oohashi

  • Importance of Shank3 Protein in Regulating Metabotropic Glutamate Receptor 5 (mGluR5) Expression and Signaling at Synapses

    Chiara Verpelli;Elena Dvoretskova;Cinzia Vicidomini;Francesca Rossi

  • Local sharing as a predominant determinant of synaptic matrix molecular dynamics

    Shlomo Tsuriel;Ran Geva;Pedro Zamorano;Thomas Dresbach

Frequent Co-Authors

Albert C. Ludolph
Albert C. Ludolph University of Ulm
Eckart D. Gundelfinger
Eckart D. Gundelfinger Leibniz Institute for Neurobiology
Craig C. Garner
Craig C. Garner Charité - University Medicine Berlin
Michael R. Kreutz
Michael R. Kreutz Leibniz Institute for Neurobiology
Thomas Bourgeron
Thomas Bourgeron Université Paris Cité
Maria Angela Vandelli
Maria Angela Vandelli University of Modena and Reggio Emilia
Carlo Sala
Carlo Sala University of Milan
Jan Kassubek
Jan Kassubek University of Ulm
Markus Huber-Lang
Markus Huber-Lang University of Ulm
Constanze I. Seidenbecher
Constanze I. Seidenbecher Leibniz Institute for Neurobiology

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