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Guoping Feng

Guoping Feng

D-Index & Metrics

Neuroscience

D-Index
102
Citations
42469
World Ranking
703
National Ranking
394

Overview

Guoping Feng is a researcher affiliated with MIT in the United States, with a significant body of work spanning biochemistry, genetics, molecular biology, and neuroscience. Their research focuses on several specialized areas, including molecular biology, cellular and molecular neuroscience, cognitive neuroscience, genetics, and biophysics.

The main topics of their research encompass single-cell and spatial transcriptomics, neuroscience and neuropharmacology research, neural dynamics and brain function, neuroinflammation and neurodegeneration mechanisms, cell image analysis techniques, CRISPR and genetic engineering, and neurogenesis and neuroplasticity mechanisms.

Guoping Feng has published extensively, with notable papers in leading journals. Some of the recent publications include:

  • A multimodal cell census and atlas of the mammalian primary motor cortex, 2021, Nature
  • Multi-animal pose estimation, identification and tracking with DeepLabCut, 2022, Nature Methods
  • AAV capsid variants with brain-wide transgene expression and decreased liver targeting after intravenous delivery in mouse and marmoset, 2021, Nature Neuroscience
  • Innovations present in the primate interneuron repertoire, 2020, Nature
  • Viral manipulation of functionally distinct interneurons in mice, non-human primates and humans, 2020, Nature Neuroscience

Their research has been disseminated through several publication venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature
  • Zenodo (CERN European Organization for Nuclear Research)
  • Nature Neuroscience
  • Neuron

Frequent collaborators in their research include:

  • Qiangge Zhang
  • Fenna M. Krienen
  • Steven A. McCarroll
  • William Menegas
  • Ricardo C.H. del Rosario

The combination of these research fields, topics, and collaborations highlights a broad interdisciplinary approach with a focus on advancing understanding in molecular and cellular mechanisms underlying neuroscience, genetic engineering, and brain function.

Best Publications

  • Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP.

    Guoping Feng;Rebecca H. Mellor;Michael Bernstein;Cynthia Keller-Peck

  • Long-term in vivo imaging of experience-dependent synaptic plasticity in adult cortex

    Joshua T. Trachtenberg;Brian E. Chen;Graham W. Knott;Guoping Feng

  • CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling

    Randall J. Platt;Sidi Chen;Yang Zhou;Michael J. Yim

  • Shank3 mutant mice display autistic-like behaviours and striatal dysfunction

    João Peça;Cátia Feliciano;Jonathan T. Ting;Wenting Wang

  • Next-Generation Optical Technologies for Illuminating Genetically Targeted Brain Circuits

    Karl Deisseroth;Guoping Feng;Ania K. Majewska;Gero Miesenböck

  • SynGO : An Evidence-Based, Expert-Curated Knowledge Base for the Synapse

    Frank Koopmans;Pim van Nierop;Maria Andres-Alonso;Andrea Byrnes

  • Cortico-striatal synaptic defects and OCD-like behaviours in Sapap3 -mutant mice

    Jeffrey M. Welch;Jing Lu;Ramona M. Rodriguiz;Nicholas C. Trotta

  • A transcription activator-like effector toolbox for genome engineering

    Neville E Sanjana;Le Cong;Le Cong;Le Cong;Yang Zhou;Yang Zhou;Margaret M Cunniff;Margaret M Cunniff

  • In Vivo Light-Induced Activation of Neural Circuitry in Transgenic Mice Expressing Channelrhodopsin-2

    Benjamin R. Arenkiel;Joao Peca;Joao Peca;Ian G. Davison;Ian G. Davison;Catia Feliciano

  • Sustained axon regeneration induced by co-deletion of PTEN and SOCS3

    Fang Sun;Kevin K. Park;Stephane Belin;Dongqing Wang

  • Flow of Cortical Activity Underlying a Tactile Decision in Mice

    Zengcai V. Guo;Nuo Li;Daniel Huber;Eran Ophir

  • Comparative cellular analysis of motor cortex in human, marmoset and mouse

    Trygve E. Bakken;Nikolas L. Jorstad;Qiwen Hu;Blue B. Lake

  • Cell type-specific channelrhodopsin-2 transgenic mice for optogenetic dissection of neural circuitry function

    Shengli Zhao;Jonathan T Ting;Jonathan T Ting;Hisham E Atallah;Li Qiu

  • Acute Brain Slice Methods for Adult and Aging Animals: Application of Targeted Patch Clamp Analysis and Optogenetics

    Jonathan T. Ting;Tanya L. Daigle;Tanya L. Daigle;Qian Chen;Guoping Feng

  • SHANK proteins: roles at the synapse and in autism spectrum disorder

    Patricia Monteiro;Guoping Feng

  • Fast modulation of visual perception by basal forebrain cholinergic neurons

    Lucas Pinto;Michael J Goard;Michael J Goard;Daniel Estandian;Min Xu

  • A viral strategy for targeting and manipulating interneurons across vertebrate species

    Jordane Dimidschstein;Jordane Dimidschstein;Qian Chen;Robin Tremblay;Stephanie L. Rogers

  • Dual requirement for gephyrin in glycine receptor clustering and molybdoenzyme activity.

    Guoping Feng;Hartmut Tintrup;Joachim Kirsch;Mia C. Nichol

  • High-speed mapping of synaptic connectivity using photostimulation in Channelrhodopsin-2 transgenic mice

    H. Wang;J. Peca;M. Matsuzaki;K. Matsuzaki

  • Optogenetic Stimulation of Lateral Orbitofronto-Striatal Pathway Suppresses Compulsive Behaviors

    Eric Burguière;Patrícia Monteiro;Guoping Feng;Ann M. Graybiel

  • Neurotechnique Imaging Neuronal Subsets in Transgenic Mice Expressing Multiple Spectral Variants of GFP

    Guoping Feng;Rebecca H. Mellor;Michael Bernstein;Cynthia Keller-Peck

Frequent Co-Authors

Jonathan T. Ting
Jonathan T. Ting Allen Institute for Brain Science
Joshua R. Sanes
Joshua R. Sanes Harvard University
Karl Deisseroth
Karl Deisseroth Stanford University
Gord Fishell
Gord Fishell Harvard Medical School
Steven A. McCarroll
Steven A. McCarroll Harvard University
Jeff W. Lichtman
Jeff W. Lichtman Harvard University

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