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Neuroscience

D-Index
86
Citations
57829
World Ranking
1267
National Ranking
643

Overview

Ed S. Lein is affiliated with the University of Washington in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Neuroscience. Within these domains, they have contributed extensively to Molecular Biology, Neurology, Biophysics, Cognitive Neuroscience, and Cellular and Molecular Neuroscience.

The main topics covered in their work include Single-cell and spatial transcriptomics, Neuroinflammation and Neurodegeneration Mechanisms, Cell Image Analysis Techniques, Neural dynamics and brain function, Neuroscience and Neuropharmacology Research, RNA Research and Splicing, and Bioinformatics and Genomic Networks.

They have collaborated frequently with a number of researchers, including:

  • Rebecca D. Hodge
  • Trygve E. Bakken
  • Jeremy A. Miller
  • Kimberly A. Smith
  • Boaz P. Levi

Ed S. Lein has published numerous papers in a variety of respected venues. Frequent publication outlets include bioRxiv (Cold Spring Harbor Laboratory), Science, Alzheimer's & Dementia, Cell Reports, and Nature Communications.

Some of their recent publications are:

  • Transcriptomic diversity of cell types across the adult human brain, 2023, Science
  • A multimodal cell census and atlas of the mammalian primary motor cortex, 2021, Nature
  • Integrated Morphoelectric and Transcriptomic Classification of Cortical GABAergic Cells, 2020, Cell
  • Expansion sequencing: Spatially precise in situ transcriptomics in intact biological systems, 2021, Science
  • Local connectivity and synaptic dynamics in mouse and human neocortex, 2022, Science

Best Publications

  • A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

    Linda Madisen;Theresa A Zwingman;Susan M Sunkin;Seung Wook Oh

  • Genome-wide atlas of gene expression in the adult mouse brain

    Ed S. Lein;Michael J. Hawrylycz;Nancy Ao;Mikael Ayres

  • An anatomically comprehensive atlas of the adult human brain transcriptome

    Michael J. Hawrylycz;Ed S. Lein;Angela L. Guillozet-Bongaarts;Elaine H. Shen

  • The complete genome sequence of a Neanderthal from the Altai Mountains

    Kay Prüfer;Fernando Racimo;Nick Patterson;Flora Jay

  • Shared and distinct transcriptomic cell types across neocortical areas

    Bosiljka Tasic;Zizhen Yao;Lucas T. Graybuck;Kimberly A. Smith

  • Wnt signalling regulates adult hippocampal neurogenesis

    Dieter Chichung Lie;Sophia A. Colamarino;Hong Jun Song;Hong Jun Song;Laurent Désiré

  • Functional organization of the hippocampal longitudinal axis

    Bryan A. Strange;Menno P. Witter;Ed S. Lein;Edvard I. Moser

  • Conserved cell types with divergent features in human versus mouse cortex.

    Rebecca D. Hodge;Trygve E. Bakken;Jeremy A. Miller;Kimberly A. Smith

  • The Human Cell Atlas

    Aviv Regev;Aviv Regev;Aviv Regev;Sarah A Teichmann;Sarah A Teichmann;Sarah A Teichmann;Eric S Lander;Eric S Lander;Eric S Lander;Ido Amit

  • Transcriptional landscape of the prenatal human brain

    Jeremy A. Miller;Song Lin Ding;Susan M. Sunkin;Kimberly A. Smith

  • Coexpression Networks Implicate Human Midfetal Deep Cortical Projection Neurons in the Pathogenesis of Autism

    A. Jeremy Willsey;A. Jeremy Willsey;Stephan J. Sanders;Stephan J. Sanders;Mingfeng Li;Shan Dong;Shan Dong

  • Functional identification of an aggression locus in the mouse hypothalamus

    Dayu Lin;Maureen P. Boyle;Piotr Dollar;Hyosang Lee

  • Disruptive CHD8 Mutations Define a Subtype of Autism Early in Development

    Raphael Bernier;Christelle Golzio;Bo Xiong;Holly A. Stessman

  • GENETIC IDENTIFICATION OF BRAIN CELL TYPES UNDERLYING SCHIZOPHRENIA

    Nathan G. Skene;Nathan G. Skene;Julien Bryois;Trygve E. Bakken;Gerome Breen;Gerome Breen

  • Integrative functional genomic analysis of human brain development and neuropsychiatric risks

    Mingfeng Li;Gabriel Santpere;Yuka Imamura Kawasawa;Yuka Imamura Kawasawa;Oleg V Evgrafov

  • Patches of Disorganization in the Neocortex of Children with Autism

    Rich Stoner;Maggie L. Chow;Maureen P. Boyle;Susan M. Sunkin

  • Comparative cellular analysis of motor cortex in human, marmoset and mouse

    Trygve E. Bakken;Nikolas L. Jorstad;Qiwen Hu;Blue B. Lake

  • Transcriptomic diversity of cell types across the adult human brain

    Unknown

  • Canonical Genetic Signatures of the Adult Human Brain

    Michael Hawrylycz;Jeremy A. Miller;Vilas Menon;David Feng

  • An anatomic transcriptional atlas of human glioblastoma

    Ralph B. Puchalski;Nameeta Shah;Jeremy Miller;Rachel Dalley

  • Single-nucleus and single-cell transcriptomes compared in matched cortical cell types.

    Trygve E. Bakken;Rebecca D. Hodge;Jeremy A. Miller;Zizhen Yao

  • Adolescent mental health—Opportunity and obligation

    Francis S. Lee;Hakon Heimer;Jay N. Giedd;Edward S Lein

  • Differential connectivity and response dynamics of excitatory and inhibitory neurons in visual cortex.

    Sonja B Hofer;Ho Ko;Bruno Pichler;Bruno Pichler;Joshua T Vogelstein

Frequent Co-Authors

Michael Hawrylycz
Michael Hawrylycz Allen Institute for Brain Science
Hongkui Zeng
Hongkui Zeng Allen Institute for Brain Science
Jonathan T. Ting
Jonathan T. Ting Allen Institute for Brain Science
Amy Bernard
Amy Bernard Kavli Foundation
Christof Koch
Christof Koch Allen Institute for Brain Science
Lydia Ng
Lydia Ng Allen Institute for Brain Science
Jeffrey G. Ojemann
Jeffrey G. Ojemann University of Washington
Zizhen Yao
Zizhen Yao Allen Institute for Brain Science
Ryder P. Gwinn
Ryder P. Gwinn Evergreen Health Medical Center
Aviv Regev
Aviv Regev Genentech

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