D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Neuroscience D-index 108 Citations 56,246 178 World Ranking 197 National Ranking 123

Research.com Recognitions

Awards & Achievements

2015 - Member of the National Academy of Sciences

2015 - The Brain Prize, Lundbeck Foundation For invention, refinement and use of two-photon microscopy to provide detailed, dynamic images of activity in individual nerve cells, dendrites and synapses, thereby transforming the study of development, plasticity and functional circuitry of the brain

Overview

What is he best known for?

The fields of study he is best known for:

  • Neuroscience
  • Neuron
  • Gene

His scientific interests lie mostly in Neuroscience, Anatomy, Dendritic spine, Barrel cortex and Cerebral cortex. He focuses mostly in the field of Neuroscience, narrowing it down to topics relating to Synaptic plasticity and, in certain cases, Long-term potentiation. The various areas that he examines in his Anatomy study include Neocortex, Biophysics, Sensory system and GCaMP, Calcium imaging.

His work deals with themes such as Neuroplasticity and In vivo, which intersect with Neocortex. In the field of Dendritic spine, his study on Dendritic filopodia overlaps with subjects such as Time constant. The Cerebral cortex study combines topics in areas such as Electrophysiology, Photostimulation and Somatosensory system.

His most cited work include:

  • Ultrasensitive fluorescent proteins for imaging neuronal activity. (3526 citations)
  • Long-term in vivo imaging of experience-dependent synaptic plasticity in adult cortex (1561 citations)
  • Direct observation of kinesin stepping by optical trapping interferometry (1513 citations)

What are the main themes of his work throughout his whole career to date?

Karel Svoboda mainly focuses on Neuroscience, Barrel cortex, Dendritic spine, Anatomy and Biophysics. In most of his Neuroscience studies, his work intersects topics such as Synaptic plasticity. His Barrel cortex study integrates concerns from other disciplines, such as Photostimulation, Neocortex, Cerebral cortex, Excitatory postsynaptic potential and Neuroplasticity.

He works mostly in the field of Excitatory postsynaptic potential, limiting it down to topics relating to Postsynaptic potential and, in certain cases, Neuron and Synapse, as a part of the same area of interest. His Dendritic spine research includes elements of Long-term potentiation, Calcium channel, Spine and Cell biology. In his study, Microscopy is inextricably linked to Fluorescence, which falls within the broad field of Biophysics.

He most often published in these fields:

  • Neuroscience (63.87%)
  • Barrel cortex (23.36%)
  • Dendritic spine (19.71%)

What were the highlights of his more recent work (between 2018-2021)?

  • Neuroscience (63.87%)
  • Biological neural network (10.58%)
  • Motor cortex (12.41%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in Neuroscience, Biological neural network, Motor cortex, Optogenetics and Sensory system. His work on Electrophysiology, Neural activity and Excitatory postsynaptic potential as part of general Neuroscience study is frequently linked to Dynamics and Attractor, therefore connecting diverse disciplines of science. His work focuses on many connections between Electrophysiology and other disciplines, such as Calcium imaging, that overlap with his field of interest in Soma, Dendrite, Pyramidal cell and Dendritic spine.

His work in Biological neural network addresses issues such as Photostimulation, which are connected to fields such as Neocortex and Inhibitory postsynaptic potential. He interconnects Cluster analysis and Thalamus in the investigation of issues within Motor cortex. His Sensory system research is multidisciplinary, relying on both Somatosensory system, Perception and Cortex.

Between 2018 and 2021, his most popular works were:

  • High-performance calcium sensors for imaging activity in neuronal populations and microcompartments (230 citations)
  • Bright and photostable chemigenetic indicators for extended in vivo voltage imaging. (149 citations)
  • Reconstruction of 1,000 Projection Neurons Reveals New Cell Types and Organization of Long-Range Connectivity in the Mouse Brain (115 citations)

In his most recent research, the most cited papers focused on:

  • Neuroscience
  • Neuron
  • Gene

His primary areas of investigation include Neuroscience, Optogenetics, Biological neural network, Calcium imaging and Motor cortex. His studies in Frontal cortex, Sensory system, Excitatory postsynaptic potential, Inhibitory postsynaptic potential and GABAergic are all subfields of Neuroscience research. He combines subjects such as Temporal resolution, Fluorescence, Förster resonance energy transfer, Premovement neuronal activity and Zebrafish with his study of Optogenetics.

His Biological neural network research incorporates themes from Neural activity, Resolution and Volumetric imaging. His Calcium imaging research is multidisciplinary, incorporating elements of Preclinical imaging, Neuron and Green fluorescent protein. His research in Motor cortex tackles topics such as Electrophysiology which are related to areas like Soma, Cluster analysis, Dendrite, Pyramidal cell and Dendritic spine.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Ultrasensitive fluorescent proteins for imaging neuronal activity.

Tsai-Wen Chen;Trevor J. Wardill;Trevor J. Wardill;Yi Sun;Stefan R. Pulver.
Nature (2013)

4087 Citations

Biological applications of optical forces

Karel Svoboda;Steven M. Block.
Annual Review of Biophysics and Biomolecular Structure (1994)

2304 Citations

Direct observation of kinesin stepping by optical trapping interferometry

Karel Svoboda;Christoph F. Schmidt;Christoph F. Schmidt;Bruce J. Schnapp;Steven M. Block.
Nature (1993)

2303 Citations

Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators

Lin Tian;S Andrew Hires;Tianyi Mao;Daniel Huber.
Nature Methods (2009)

2058 Citations

Long-term in vivo imaging of experience-dependent synaptic plasticity in adult cortex

Joshua T. Trachtenberg;Brian E. Chen;Graham W. Knott;Guoping Feng.
Nature (2002)

2037 Citations

Experience-dependent structural synaptic plasticity in the mammalian brain.

Anthony Holtmaat;Karel Svoboda.
Nature Reviews Neuroscience (2009)

1690 Citations

Rapid Spine Delivery and Redistribution of AMPA Receptors After Synaptic NMDA Receptor Activation

Song-Hai Shi;Yasunori Hayashi;Ronald S. Petralia;Shahid H. Zaman.
Science (1999)

1508 Citations

Rapid Dendritic Morphogenesis in CA1 Hippocampal Dendrites Induced by Synaptic Activity

M. Maletic-Savatic;R. Malinow;K. Svoboda.
Science (1999)

1398 Citations

Structure and function of dendritic spines.

Esther A Nimchinsky;Bernardo L Sabatini;Karel Svoboda.
Annual Review of Physiology (2002)

1291 Citations

Optimization of a GCaMP calcium indicator for neural activity imaging.

Jasper Akerboom;Tsai Wen Chen;Trevor J. Wardill;Lin Tian;Lin Tian.
The Journal of Neuroscience (2012)

1147 Citations

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