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Bernardo L. Sabatini

Bernardo L. Sabatini

D-Index & Metrics

Neuroscience

D-Index
100
Citations
38887
World Ranking
758
National Ranking
420

Research.com Recognitions

  • 2019 - Member of the National Academy of Sciences
  • 2017 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2014 - Fellow of the American Academy of Arts and Sciences

Overview

Bernardo L. Sabatini is affiliated with Harvard Medical School in the United States. Their research activity spans several interconnected fields, primarily focusing on Neuroscience with significant overlap into Biochemistry, Genetics, and Molecular Biology.

Their work is concentrated at the intersection of Cellular and Molecular Neuroscience, Molecular Biology, and Cognitive Neuroscience, incorporating elements of Biophysics and Endocrinology, Diabetes, and Metabolism. Key topics in Sabatini's research include Neuroscience and Neuropharmacology Research, Neural dynamics and brain function, Photoreceptor and optogenetics research, Receptor Mechanisms and Signaling, Neuroscience and Neural Engineering, Advanced Fluorescence Microscopy Techniques, and Neurotransmitter Receptor Influence on Behavior.

Recent notable papers authored or co-authored by Sabatini include:

  • "Viral manipulation of functionally distinct interneurons in mice, non-human primates and humans," 2020, Nature Neuroscience
  • "Caveolae in CNS arterioles mediate neurovascular coupling," 2020, Nature
  • "Spontaneous behaviour is structured by reinforcement without explicit reward," 2023, Nature
  • "Imaging Neurotransmitter and Neuromodulator Dynamics In Vivo with Genetically Encoded Indicators," 2020, Neuron
  • "Anatomically segregated basal ganglia pathways allow parallel behavioral modulation," 2020, Nature Neuroscience

Sabatini has collaborated frequently with several co-authors, including Wengang Wang, Filippo Pisano, Ferruccio Pisanello, Barbara Spagnolo, and Marco Pisanello. These collaborations reflect sustained research efforts in related areas of neuroscience and molecular biology.

Their research outputs have appeared in a range of scientific journals and platforms, with a high volume of publications in bioRxiv (Cold Spring Harbor Laboratory). Other frequent publication venues include Nature, eLife, Zenodo (CERN European Organization for Nuclear Research), and Neuron.

Their scholarly work and contributions to the scientific community have been recognized through several awards and honors. These include election as a Member of the National Academy of Sciences in 2019, Fellowship of the American Association for the Advancement of Science (AAAS) in 2017, and Fellowship of the American Academy of Arts and Sciences in 2014.

Best Publications

  • Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory.

    Ganesh M Shankar;Shaomin Li;Tapan H Mehta;Amaya Garcia-Munoz

  • Natural Oligomers of the Alzheimer Amyloid-β Protein Induce Reversible Synapse Loss by Modulating an NMDA-Type Glutamate Receptor-Dependent Signaling Pathway

    Ganesh M. Shankar;Brenda L. Bloodgood;Matthew Townsend;Dominic M. Walsh

  • Structure and function of dendritic spines.

    Esther A Nimchinsky;Bernardo L Sabatini;Karel Svoboda

  • All-optical electrophysiology in mammalian neurons using engineered microbial rhodopsins

    Daniel R Hochbaum;Yongxin Zhao;Samouil L Farhi;Nathan Klapoetke

  • The Life Cycle of Ca2+ Ions in Dendritic Spines

    Bernardo L. Sabatini;Thomas G. Oertner;Karel Svoboda

  • Dopaminergic Modulation of Synaptic Transmission in Cortex and Striatum

    Nicolas X. Tritsch;Bernardo L. Sabatini

  • Efficient and accurate extraction of in vivo calcium signals from microendoscopic video data

    Pengcheng Zhou;Shanna L Resendez;Jose Rodriguez-Romaguera;Jessica C Jimenez

  • Anatomical and physiological plasticity of dendritic spines.

    Veronica A. Alvarez;Bernardo L. Sabatini

  • Dopaminergic neurons inhibit striatal output through non-canonical release of GABA

    Nicolas X. Tritsch;Jun B. Ding;Jun B. Ding;Bernardo L. Sabatini

  • Calcium control of transmitter release at a cerebellar synapse

    I.M. Mintz;B.L. Sabatini;W.G. Regehr

  • Regulation of neuronal morphology and function by the tumor suppressors Tsc1 and Tsc2

    Sohail F Tavazoie;Veronica A Alvarez;Dennis A Ridenour;David J Kwiatkowski

  • Timing of neurotransmission at fast synapses in the mammalian brain.

    Bernardo L. Sabatini;Wade G. Regehr

  • Single-cell analysis of experience-dependent transcriptomic states in the mouse visual cortex.

    Sinisa Hrvatin;Daniel R. Hochbaum;Daniel R. Hochbaum;M. Aurel Nagy;Marcelo Cicconet

  • SK channels and NMDA receptors form a Ca2+-mediated feedback loop in dendritic spines.

    Thu Jennifer Ngo-Anh;Brenda L Bloodgood;Michael Lin;Bernardo L Sabatini

  • Synapses and Alzheimer’s Disease

    Morgan Sheng;Bernardo L. Sabatini;Thomas C. Südhof

  • Estimating intracellular calcium concentrations and buffering without wavelength ratioing.

    M. Maravall;Z.F. Mainen;B.L. Sabatini;K. Svoboda

  • The Striatum Organizes 3D Behavior via Moment-to-Moment Action Selection

    Jeffrey E. Markowitz;Jeffrey E. Markowitz;Winthrop F. Gillis;Celia C. Beron;Celia C. Beron;Shay Q. Neufeld;Shay Q. Neufeld

  • Glutamate induces de novo growth of functional spines in developing cortex

    Hyung Bae Kwon;Bernardo L. Sabatini

  • Neuronal activity regulates diffusion across the neck of dendritic spines.

    Brenda L. Bloodgood;Bernardo L. Sabatini

  • State-Dependent Calcium Signaling in Dendritic Spines of Striatal Medium Spiny Neurons

    Adam G. Carter;Bernardo L. Sabatini

  • All-optical electrophysiology in mammalian neurons using engineered microbial rhodopsins

    Daniel R Hochbaum;Yongxin Zhao;Samouil L Farhi;Christopher A Werley

Frequent Co-Authors

Massimo De Vittorio
Massimo De Vittorio University of Salento
Karel Svoboda
Karel Svoboda Allen Institute
Michael J. Higley
Michael J. Higley Yale University
Chenghua Gu
Chenghua Gu Harvard University
Wade G. Regehr
Wade G. Regehr Harvard Medical School
John A. Assad
John A. Assad Harvard University
Bradford B. Lowell
Bradford B. Lowell Beth Israel Deaconess Medical Center
Veronica A. Alvarez
Veronica A. Alvarez National Institutes of Health
Morgan Sheng
Morgan Sheng Broad Institute

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