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D-Index & Metrics

Neuroscience

D-Index
44
Citations
10956
World Ranking
7065
National Ranking
3055

Research.com Recognitions

  • 2014 - National Institutes of Health Director's Pioneer Award
  • 2008 - Fellow of Alfred P. Sloan Foundation

Overview

Chenghua Gu is affiliated with Harvard University in the United States and has contributed extensively to the fields of neuroscience, biochemistry, genetics, molecular biology, and medicine. Their research primarily focuses on barrier structure and function studies, caveolin-1 and cellular processes, neuroscience and neuropharmacology research, traumatic brain injury and neurovascular disturbances, mitochondrial function and pathology, receptor mechanisms and signaling, and cell adhesion molecules research.

Gu's frequent publication venues include bioRxiv (Cold Spring Harbor Laboratory), Nature, Physiology, Nature Reviews. Neuroscience, and eLife.

  • Neuronal regulation of the blood-brain barrier and neurovascular coupling, 2020, Nature Reviews. Neuroscience
  • Caveolae in CNS arterioles mediate neurovascular coupling, 2020, Nature
  • Cortical ChAT+ neurons co-transmit acetylcholine and GABA in a target- and brain-region-specific manner, 2020, eLife
  • Pericyte-to-endothelial cell signaling via vitronectin-integrin regulates blood-CNS barrier, 2022, Neuron
  • The Neurovasculome: Key Roles in Brain Health and Cognitive Impairment: A Scientific Statement From the American Heart Association/American Stroke Association, 2023, Stroke

Frequent coauthors collaborating with Gu include:

  • Luke Kaplan
  • Brian Wai Chow
  • Vicente Nuñez
  • Adam Granger
  • Karina Bistrong

The main fields of study associated with Gu's work are neuroscience, biochemistry, genetics and molecular biology, and medicine. Their research spans several subfields, including neurology, molecular biology, cellular and molecular neuroscience, cell biology, and radiology, nuclear medicine and imaging.

Chenghua Gu has been recognized with awards such as the National Institutes of Health Director's Pioneer Award in 2014 and was named a Fellow of the Alfred P. Sloan Foundation in 2008.

Best Publications

  • Mfsd2a is critical for the formation and function of the blood–brain barrier

    Ayal Ben-Zvi;Baptiste Lacoste;Esther Kur;Benjamin J. Andreone

  • Neuropilin-1 Conveys Semaphorin and VEGF Signaling during Neural and Cardiovascular Development

    Chenghua Gu;E. Rene Rodriguez;Dorothy V. Reimert;Tianzhi Shu

  • Semaphorin 3E and plexin-D1 control vascular pattern independently of neuropilins.

    Chenghua Gu;Yutaka Yoshida;Jean Livet;Dorothy V. Reimert

  • Blood-Brain Barrier Permeability Is Regulated by Lipid Transport-Dependent Suppression of Caveolae-Mediated Transcytosis.

    Benjamin J. Andreone;Brian Wai Chow;Aleksandra Tata;Baptiste Lacoste

  • Development and Cell Biology of the Blood-Brain Barrier.

    Urs H Langen;Swathi Ayloo;Chenghua Gu

  • The molecular constituents of the blood-brain barrier.

    Brian Wai Chow;Chenghua Gu

  • Neuronal regulation of the blood–brain barrier and neurovascular coupling

    Luke Kaplan;Brian W. Chow;Chenghua Gu

  • Semaphorin 3E–Plexin-D1 signaling regulates VEGF function in developmental angiogenesis via a feedback mechanism

    Jiha Kim;Won Jong Oh;Nicholas Gaiano;Yutaka Yoshida

  • Characterization of neuropilin-1 structural features that confer binding to semaphorin 3A and vascular endothelial growth factor 165

    Chenghua Gu;Brian J. Limberg;G. Brian Whitaker;Ben Perman

  • Distinct Roles for Secreted Semaphorin Signaling in Spinal Motor Axon Guidance

    Andrea B. Huber;Artur Kania;Tracy S. Tran;Chenghua Gu

  • Peripheral nerve-derived VEGF promotes arterial differentiation via neuropilin 1-mediated positive feedback

    Yoh-suke Mukouyama;Hans-Peter Gerber;Napoleone Ferrara;Chenghua Gu;Chenghua Gu

  • Bridging barriers: a comparative look at the blood-brain barrier across organisms.

    Natasha M. O'Brown;Sarah J. Pfau;Chenghua Gu

  • Neuronal and vascular interactions.

    Benjamin J. Andreone;Baptiste Lacoste;Chenghua Gu

  • Transcytosis at the blood-brain barrier.

    Swathi Ayloo;Chenghua Gu

  • Guidance of trunk neural crest migration requires neuropilin 2/semaphorin 3F signaling.

    Laura S. Gammill;Constanza Gonzalez;Chenghua Gu;Marianne Bronner-Fraser

  • Caveolae in CNS arterioles mediate neurovascular coupling

    Brian W. Chow;Vicente Nuñez;Luke Kaplan;Adam J. Granger;Adam J. Granger

  • Midbrain dopamine neurons sustain inhibitory transmission using plasma membrane uptake of GABA, not synthesis

    Nicolas X Tritsch;Won-Jong Oh;Chenghua Gu;Bernardo L Sabatini

  • Oligodendrocyte Apoptosis Mediated by Caspase Activation

    Chenghua Gu;Patrizia Casaccia-Bonnefil;Anu Srinivasan;Moses V. Chao

  • Vascular endothelial growth factor controls neuronal migration and cooperates with Sema3A to pattern distinct compartments of the facial nerve.

    Quenten Schwarz;Chenghua Gu;Hajime Fujisawa;Kimberly Sabelko

  • Neuroligin-1-dependent competition regulates cortical synaptogenesis and synapse number

    Hyung Bae Kwon;Yevgenia Kozorovitskiy;Won Jong Oh;Rui T. Peixoto

Frequent Co-Authors

Bernardo L. Sabatini
Bernardo L. Sabatini Harvard Medical School
David D. Ginty
David D. Ginty Howard Hughes Medical Institute
Alex L. Kolodkin
Alex L. Kolodkin Johns Hopkins University School of Medicine
Moses V. Chao
Moses V. Chao New York University
Linda J. Richards
Linda J. Richards Washington University in St. Louis
Thomas M. Jessell
Thomas M. Jessell Columbia University
Yutaka Yoshida
Yutaka Yoshida Cornell University
Christopher E. Henderson
Christopher E. Henderson Biogen (United States)
Cenk Ayata
Cenk Ayata Harvard University
Marianne Bronner-Fraser
Marianne Bronner-Fraser California Institute of Technology

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Exploring these online options can help neuroscience graduates find fulfilling roles across healthcare, education, and community services while maximizing career growth and minimizing student debt.

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