World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
85
Citations
27821
World Ranking
1310
National Ranking
677

Medicine

D-Index
85
Citations
27831
World Ranking
14557
National Ranking
7369

Overview

Luciano Adorini is affiliated with Intercept Pharmaceuticals in the United States and has made significant contributions to the field of medicine, particularly focusing on hepatology and related subfields. Their work encompasses aspects of oncology, surgery, epidemiology, molecular biology, and multiple areas within liver disease research.

Their research covers specific areas such as drug transport and resistance mechanisms, liver disease diagnosis and treatment, immunity related to liver diseases, liver disease and transplantation, Helicobacter pylori-associated gastroenterology, organ transplantation techniques and outcomes, and pediatric hepatobiliary diseases and treatments.

Adorini has published extensively in prominent journals, with frequent publication venues including:

  • Journal of Hepatology
  • American Journal of Physiology-Gastrointestinal and Liver Physiology
  • Digestive and Liver Disease
  • Gastroenterology
  • Liver International

Recent notable papers authored or coauthored by Luciano Adorini comprise:

  • FXR agonists in NASH treatment, 2023, Journal of Hepatology
  • Obeticholic acid and INT-767 modulate collagen deposition in a NASH in vitro model, 2020, Scientific Reports
  • The role of FXR and TGR5 in reversing and preventing progression of Western diet-induced hepatic steatosis, inflammation, and fibrosis in mice, 2022, Journal of Biological Chemistry
  • An integrated analysis of fecal microbiome and metabolomic features distinguish non-cirrhotic NASH from healthy control populations, 2023, Hepatology
  • FXR agonists INT-787 and OCA increase RECK and inhibit liver steatosis and inflammation in diet-induced ob/ob mouse model of NASH, 2023, Liver International

Throughout their research career, Adorini has collaborated frequently with several coauthors, including:

  • G. Palladini
  • Andrea Ferrigno
  • Mariapia Vairetti
  • Laura Giuseppina Di Pasqua
  • Marta Cagna

The main disciplines of study covered by Luciano Adorini's publications are highly concentrated in medicine, with a total of 72 publications, and subfields such as:

  • Oncology (19 publications)
  • Surgery (16 publications)
  • Epidemiology (15 publications)
  • Hepatology (13 publications)
  • Molecular Biology (7 publications)

Luciano Adorini's work especially addresses liver diseases with a focus on nonalcoholic steatohepatitis (NASH) and the role of farnesoid X receptor (FXR) agonists, investigating both molecular mechanisms and therapeutic interventions.

Best Publications

  • 1α,25-Dihydroxyvitamin D3 Inhibits Differentiation, Maturation, Activation, and Survival of Dendritic Cells Leading to Impaired Alloreactive T Cell Activation

    Giuseppe Penna;Luciano Adorini

  • THE INTERLEUKIN-12/INTERLEUKIN-12-RECEPTOR SYSTEM: Role in Normal and Pathologic Immune Responses

    Maurice K. Gately;Louis M. Renzetti;Jeanne Magram;Alvin S. Stern

  • Maturation Stages of Mouse Dendritic Cells in Growth Factor–dependent Long-Term Cultures

    Claudia Winzler;Patrizia Rovere;Maria Rescigno;Francesca Granucci

  • Regulatory T Cells Induced by 1α,25-Dihydroxyvitamin D3 and Mycophenolate Mofetil Treatment Mediate Transplantation Tolerance

    Silvia Gregori;Mara Casorati;Susana Amuchastegui;Simona Smiroldo

  • The coming of age of 1,25-dihydroxyvitamin D3 analogs as immunomodulatory agents

    Chantal Mathieu;Luciano Adorini

  • A 1α,25-Dihydroxyvitamin D3 Analog Enhances Regulatory T-Cells and Arrests Autoimmune Diabetes in NOD Mice

    Silvia Gregori;Nadia Giarratana;Simona Smiroldo;Milan Uskokovic

  • Cardiomyocytes induce endothelial cells to trans-differentiate into cardiac muscle: Implications for myocardium regeneration

    G. Condorelli;U. Borello;L. De Angelis;M. Latronico

  • Interleukin 12 administration induces T helper type 1 cells and accelerates autoimmune diabetes in NOD mice.

    S Trembleau;G Penna;E Bosi;A Mortara

  • Regulation of T-cell responses by CNS antigen-presenting cells: different roles for microglia and astrocytes.

    Francesca Aloisi;Francesco Ria;Luciano Adorini

  • Expression of the inhibitory receptor ILT3 on dendritic cells is dispensable for induction of CD4+Foxp3+ regulatory T cells by 1,25-dihydroxyvitamin D3.

    Giuseppe Penna;Andrea Roncari;Susana Amuchastegui;Kenn C. Daniel

  • 1,25-Dihydroxyvitamin D3 selectively modulates tolerogenic properties in myeloid but not plasmacytoid dendritic cells.

    Giuseppe Penna;Susana Amuchastegui;Nadia Giarratana;Kenn C. Daniel

  • The role of IL-12 in the induction of organ-specific autoimmune diseases

    Sylvie Trembleau;Luciano Adorini;Tieno Germann;Maurice K. Gately

  • Cutting Edge: Selective Usage of Chemokine Receptors by Plasmacytoid Dendritic Cells

    Giuseppe Penna;Silvano Sozzani;Luciano Adorini

  • Seminal Plasma Cytokines and Chemokines in Prostate Inflammation: Interleukin 8 as a Predictive Biomarker in Chronic Prostatitis/Chronic Pelvic Pain Syndrome and Benign Prostatic Hyperplasia

    Giuseppe Penna;Nicola Mondaini;Susana Amuchastegui;Selene Degli Innocenti

  • The Role of Stat4 in Species-Specific Regulation of Th Cell Development by Type I IFNs

    Lars Rogge;Daniele D’Ambrosio;Mauro Biffi;Giuseppe Penna

  • The control of T cell responses by dendritic cell subsets.

    Steven D Reid;Giuseppe Penna;Luciano Adorini

  • Restructuring of the Gut Microbiome by Intermittent Fasting Prevents Retinopathy and Prolongs Survival in db/db Mice.

    Eleni Beli;Yuanqing Yan;Leni Moldovan;Cristiano P. Vieira

  • Leukocyte recruitment in the cerebrospinal fluid of mice with experimental meningitis is inhibited by an antibody to junctional adhesion molecule (JAM).

    Aldo Del Maschio;Ada De Luigi;Ines Martin-Padura;Manfred Brockhaus

  • Inhibition of Th1 development and treatment of chronic-relapsing experimental allergic encephalomyelitis by a non-hypercalcemic analogue of 1,25-dihydroxyvitamin D3

    Frank Mattner;Simona Smiroldo;Francesca Galbiati;Marc Muller

  • Microglia Are More Efficient Than Astrocytes in Antigen Processing and in Th1 But Not Th2 Cell Activation

    Francesca Aloisi;Francesco Ria;Giuseppe Penna;Luciano Adorini

  • Interleukin 12 Administration Induces T Helper Type 1 Cells and Accelerates Autoimmune Diabetes in NOD Mice By Sylvie Trembleau,* Giuseppe Penna,* Emanuele Bosi,~

    Anna Mortara;Maurice K. Gately;Luciano Adorini

Frequent Co-Authors

Giuseppe Penna
Giuseppe Penna European Institute of Oncology
Milan R. Uskokovic
Milan R. Uskokovic Roche (Switzerland)
Silvia Gregori
Silvia Gregori Vita-Salute San Raffaele University
Jean-Charles Guéry
Jean-Charles Guéry Federal University of Toulouse Midi-Pyrénées
Mario Maggi
Mario Maggi University of Florence
Linda Vignozzi
Linda Vignozzi University of Florence
Ettore Appella
Ettore Appella National Institutes of Health
Gianvito Martino
Gianvito Martino Vita-Salute San Raffaele University
Francesca Aloisi
Francesca Aloisi Istituto Superiore di Sanità
Pietro Luigi Poliani
Pietro Luigi Poliani University of Brescia

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