World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
109
Citations
41492
World Ranking
521
National Ranking
317

Medicine

D-Index
109
Citations
41647
World Ranking
5810
National Ranking
3117

Research.com Recognitions

  • 2007 - Fellow of the Royal Society of Edinburgh

Overview

Angus W. Thomson is affiliated with the University of Pittsburgh in the United States. Their research focuses primarily on medicine and immunology and microbiology, producing a significant body of work that spans immunology, surgery, transplantation, oncology, and hepatology. The scientist's publications encompass topics such as immunotherapy and immune responses, immune cell function and interaction, T-cell and B-cell immunology, organ transplantation techniques and outcomes, renal transplantation outcomes and treatments, broader transplantation methods and outcomes, and neuroinflammation and neurodegeneration mechanisms.

Thomson has frequently published in several academic journals, with notable recurring venues including Transplantation, American Journal of Transplantation, Frontiers in Immunology, Kidney International, and Immunity. The scientist's frequent coauthors reflect collaborations with peers like Alan F. Zahorchak, Fadi G. Lakkis, Diana Metes, Mohamed Ezzelarab, and Abhinav Humar.

Key recent papers authored or coauthored by Thomson are:

  • "Treg cell-derived osteopontin promotes microglia-mediated white matter repair after ischemic stroke" (2021, Immunity)
  • "Understanding, predicting and achieving liver transplant tolerance: from bench to bedside" (2020, Nature Reviews Gastroenterology & Hepatology)
  • "In situ recruitment of regulatory T cells promotes donor-specific tolerance in vascularized composite allotransplantation" (2020, Science Advances)
  • "Neuroprotection against ischemic stroke requires a specific class of early responder T cells in mice" (2022, Journal of Clinical Investigation)
  • "Donor-derived regulatory dendritic cell infusion results in host cell cross-dressing and T cell subset changes in prospective living donor liver transplant recipients" (2020, American Journal of Transplantation)

The researcher's contributions are recognized within their professional community, including an award as a Fellow of the Royal Society of Edinburgh in 2007.

Best Publications

  • Tolerogenic dendritic cells and the quest for transplant tolerance.

    Adrian E. Morelli;Angus W. Thomson

  • Endocytosis, intracellular sorting, and processing of exosomes by dendritic cells.

    Adrian E. Morelli;Adriana T. Larregina;William J. Shufesky;Mara L. G. Sullivan

  • Antigen-presenting cell function in the tolerogenic liver environment.

    Angus W Thomson;Percy A Knolle

  • Immunoregulatory functions of mTOR inhibition

    Angus W. Thomson;Hēth R. Turnquist;Giorgio Raimondi

  • Dendritic cells: emerging pharmacological targets of immunosuppressive drugs.

    Holger Hackstein;Angus W. Thomson

  • Rapamycin-conditioned dendritic cells are poor stimulators of allogeneic CD4+ T cells, but enrich for antigen-specific Foxp3+ T regulatory cells and promote organ transplant tolerance.

    Hēth R. Turnquist;Giorgio Raimondi;Alan F. Zahorchak;Ryan T. Fischer

  • Organ transplantation—how much of the promise has been realized?

    Robert I Lechler;Megan Sykes;Angus W Thomson;Laurence A Turka

  • Rapamycin inhibits IL-4—induced dendritic cell maturation in vitro and dendritic cell mobilization and function in vivo

    Holger Hackstein;Timucin Taner;Alan F. Zahorchak;Adrian E. Morelli

  • Mode of action of tacrolimus (FK506): molecular and cellular mechanisms.

    A W Thomson;C A Bonham;A Zeevi

  • Evidence for a Role of IL-17 in Organ Allograft Rejection: IL-17 Promotes the Functional Differentiation of Dendritic Cell Progenitors

    Mary A. Antonysamy;William C. Fanslow;Fumin Fu;Wei Li

  • Costimulatory Molecule-Deficient Dendritic Cell Progenitors (MHC Class II+, CD80dim, CD86-) Prolong Cardiac Allograft Survival in Nonimmunosuppressed Recipients

    Fumin Fu;Youping Li;Shiguang Qian;Lina Lu

  • Spermatogonial Stem Cell Transplantation into Rhesus Testes Regenerates Spermatogenesis Producing Functional Sperm

    Brian Peter Hermann;Meena Sukhwani;Felicity Winkler;Julia N. Pascarella

  • Dendritic cells: regulators of alloimmunity and opportunities for tolerance induction.

    Adrian E. Morelli;Angus W. Thomson

  • Internalization of circulating apoptotic cells by splenic marginal zone dendritic cells: dependence on complement receptors and effect on cytokine production

    Adrian E. Morelli;Adriana T. Larregina;William J. Shufesky;Alan F. Zahorchak

  • Bone marrow-derived dendritic cell progenitors (NLDC 145+, MHC class II+, B7-1dim, B7-2-) induce alloantigen-specific hyporesponsiveness in murine T lymphocytes.

    Lina Lu;Delbert McCaslin;Thomas E. Starzl;Angus W. Thomson

  • Treg cell-derived osteopontin promotes microglia-mediated white matter repair after ischemic stroke

    Ligen Shi;Zeyu Sun;Wei Su;Fei Xu;Fei Xu

  • Consensus document: therapeutic monitoring of tacrolimus (FK-506).

    William J. Jusko;Angus W. Thomson;John Fung;Paul McMaster

  • Propagation of Dendritic Cell Progenitors from Normal Mouse Liver Using Granulocyte/Macrophage Colony-stimulating Factor and Their Maturational Development in the Presence of Type-1 Collagen

    L. Lu;J. Woo;A. S. Rao;Youping Li

  • Apoptosis within spontaneously accepted mouse liver allografts: evidence for deletion of cytotoxic T cells and implications for tolerance induction.

    Shiguang Qian;Lina Lu;Fumin Fu;Youping Li

  • Fas ligand (CD95L) and B7 expression on dendritic cells provide counter-regulatory signals for T cell survival and proliferation.

    Lina Lu;Shiguang Qian;Pamela A. Hershberger;William A. Rudert

  • Rapamycin-Treated, Alloantigen-Pulsed Host Dendritic Cells Induce Ag-Specific T Cell Regulation and Prolong Graft Survival

    Timuçin Taner;Holger Hackstein;Zhiliang Wang;Adrian E. Morelli

Frequent Co-Authors

Lina Lu
Lina Lu Cleveland Clinic Lerner College of Medicine
John J. Fung
John J. Fung University of Chicago
Shiguang Qian
Shiguang Qian Cleveland Clinic Lerner College of Medicine
Adrian E. Morelli
Adrian E. Morelli University of Pittsburgh
Thomas E. Starzl
Thomas E. Starzl University of Pittsburgh
Noriko Murase
Noriko Murase University of Pittsburgh
Anthony J. Demetris
Anthony J. Demetris University of Pittsburgh
George V. Mazariegos
George V. Mazariegos Children's Hospital of Pittsburgh
David A. Geller
David A. Geller University of Pittsburgh
Paul D. Robbins
Paul D. Robbins University of Minnesota

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