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Immunology

D-Index
59
Citations
18137
World Ranking
3386
National Ranking
1567

Overview

Adrian E. Morelli is affiliated with the University of Pittsburgh in the United States and has a research focus primarily in immunology, microbiology, and medicine. Their work explores various intersecting fields including biochemistry, genetics, molecular biology, obstetrics and gynecology, dermatology, and cellular and molecular neuroscience.

The main subjects of Morelli's research include extracellular vesicles in disease, reproductive system and pregnancy, pregnancy and preeclampsia studies, the impact of COVID-19 on reproduction, neuropeptides and animal physiology, immune cell function and interaction, and contact dermatitis and allergies.

Frequent publication venues where Morelli's work has appeared include:

  • The Journal of Immunology
  • Cell Reports
  • Journal of Investigative Dermatology
  • American Journal of Transplantation
  • Science Translational Medicine

Notable recent papers by Adrian E. Morelli include:

  • "Graft-derived extracellular vesicles transported across subcapsular sinus macrophages elicit B cell alloimmunity after transplantation," 2021, Science Translational Medicine
  • "Neurokinin-1 Receptor Signaling Is Required for Efficient Ca2+ Flux in T-Cell-Receptor-Activated T Cells," 2020, Cell Reports
  • "Placental small extracellular vesicles: Current questions and investigative opportunities," 2020, Placenta
  • "Extracellular vesicles and immune response during pregnancy: A balancing act," 2022, Immunological Reviews
  • "Skin codelivery of contact sensitizers and neurokinin-1 receptor antagonists integrated in microneedle arrays suppresses allergic contact dermatitis," 2022, Journal of Allergy and Clinical Immunology

Adrian E. Morelli has collaborated frequently with several coauthors, including:

  • William J. Shufesky
  • Adriana T. Larregina
  • Mohna Bandyopadhyay
  • О. Н. Ткачева
  • Géza Erdös

Best Publications

  • Regulation of immune responses by extracellular vesicles

    Paul D. Robbins;Adrian E. Morelli

  • Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes

    Angela Montecalvo;Adriana T. Larregina;William J. Shufesky;Donna Beer Stolz

  • Tolerogenic dendritic cells and the quest for transplant tolerance.

    Adrian E. Morelli;Angus W. Thomson

  • Endocytosis, intracellular sorting, and processing of exosomes by dendritic cells.

    Adrian E. Morelli;Adriana T. Larregina;William J. Shufesky;Mara L. G. Sullivan

  • Rapamycin inhibits IL-4—induced dendritic cell maturation in vitro and dendritic cell mobilization and function in vivo

    Holger Hackstein;Timucin Taner;Alan F. Zahorchak;Adrian E. Morelli

  • Human placental trophoblasts confer viral resistance to recipient cells

    Elizabeth Delorme-Axford;Rogier B. Donker;Jean-Francois Mouillet;Tianjiao Chu

  • Dendritic cells: regulators of alloimmunity and opportunities for tolerance induction.

    Adrian E. Morelli;Angus W. Thomson

  • Internalization of circulating apoptotic cells by splenic marginal zone dendritic cells: dependence on complement receptors and effect on cytokine production

    Adrian E. Morelli;Adriana T. Larregina;William J. Shufesky;Alan F. Zahorchak

  • The expression profile of C19MC microRNAs in primary human trophoblast cells and exosomes

    R.B. Donker;J.F. Mouillet;T. Chu;C.A. Hubel

  • Rapamycin-Treated, Alloantigen-Pulsed Host Dendritic Cells Induce Ag-Specific T Cell Regulation and Prolong Graft Survival

    Timuçin Taner;Holger Hackstein;Zhiliang Wang;Adrian E. Morelli

  • Cytokine production by mouse myeloid dendritic cells in relation to differentiation and terminal maturation induced by lipopolysaccharide or CD40 ligation

    Adrian E. Morelli;Alan F. Zahorchak;Adriana T. Larregina;Bridget L. Colvin

  • Exosomes As a Short-Range Mechanism to Spread Alloantigen between Dendritic Cells during T Cell Allorecognition

    Angela Montecalvo;William J. Shufesky;Donna Beer Stolz;Mara G. Sullivan

  • Recombinant Adenovirus Induces Maturation of Dendritic Cells via an NF-κB-Dependent Pathway

    Adrian E. Morelli;Adriana T. Larregina;Raymond W. Ganster;Alan F. Zahorchak

  • Donor dendritic cell–derived exosomes promote allograft-targeting immune response

    Quan Liu;Quan Liu;Darling M. Rojas-Canales;Sherrie J. Divito;William J. Shufesky

  • Dermal-resident CD14+ cells differentiate into Langerhans cells.

    Adriana T. Larregina;Adrian E. Morelli;Lori A. Spencer;Alison J. Logar

  • Effects of Liver-Derived Dendritic Cell Progenitors on Th1- and Th2-Like Cytokine Responses In Vitro and In Vivo

    Ajai Khanna;Adrian E. Morelli;Cuiping Zhong;Takuya Takayama

  • Exosomes derived from genetically modified DC expressing FasL are anti-inflammatory and immunosuppressive.

    Seon Hee Kim;Nicole Bianco;Rajasree Menon;Eric R. Lechman

  • Effective Treatment of Inflammatory Disease Models with Exosomes Derived from Dendritic Cells Genetically Modified to Express IL-4

    Seon Hee Kim;Nicole R. Bianco;William J. Shufesky;Adrian E. Morelli

  • Aspirin Inhibits In Vitro Maturation and In Vivo Immunostimulatory Function of Murine Myeloid Dendritic Cells

    Holger Hackstein;Adrian E. Morelli;Adriana T. Larregina;Raymond W. Ganster

  • Neuronal and glial cell type-specific promoters within adenovirus recombinants restrict the expression of the apoptosis-inducing molecule Fas ligand to predetermined brain cell types, and abolish peripheral liver toxicity.

    Adrian E. Morelli;Adriana T. Larregina;Joseph Smith-Arica;Ricardo A. Dewey

Frequent Co-Authors

Angus W. Thomson
Angus W. Thomson University of Pittsburgh
Louis D. Falo
Louis D. Falo University of Pittsburgh
Paul D. Robbins
Paul D. Robbins University of Minnesota
Simon C. Watkins
Simon C. Watkins University of Pittsburgh
Donna B. Stolz
Donna B. Stolz University of Pittsburgh
Lina Lu
Lina Lu Cleveland Clinic Lerner College of Medicine
David K. C. Cooper
David K. C. Cooper University of Pittsburgh
Timothy R. Billiar
Timothy R. Billiar University of Pittsburgh
Yoel Sadovsky
Yoel Sadovsky University of Pittsburgh
Fadi G. Lakkis
Fadi G. Lakkis University of Pittsburgh

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