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Hong C. Shen

D-Index & Metrics

Chemistry

D-Index
41
Citations
6587
World Ranking
17747
National Ranking
295

Hong C. Shen publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where Hong C. Shen sits on this spectrum.

61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61 publications 1,295+

This scientist: 133 publications — 9th percentile

9% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

Hong C. Shen D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Hong C. Shen sits on this spectrum.

40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40 D-Index 159+

This scientist: 41 D-Index — 2nd percentile

2% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

Overview

Hong C. Shen is affiliated with Roche (Switzerland) and has contributed extensively to research in medicine and chemistry. Their work spans multiple areas including organic chemistry, molecular biology, oncology, epidemiology, and immunology.

Their research topics notably cover:

  • Synthesis and Catalytic Reactions
  • Catalytic C-H Functionalization Methods
  • Hepatitis B Virus Studies
  • Hepatitis C virus research
  • Cytokine Signaling Pathways and Interactions
  • Interferon and Immune Responses
  • Sulfur-Based Synthesis Techniques

Shen has published in several scientific journals, with frequent contributions to:

  • Journal of Medicinal Chemistry (6 publications)
  • Bioorganic & Medicinal Chemistry Letters (4 publications)
  • SSRN Electronic Journal (3 publications)
  • Cell (1 publication)
  • Cell Reports (1 publication)

Recent selected publications include:

  • Phase Separation of Disease-Associated SHP2 Mutants Underlies MAPK Hyperactivation, 2020, Cell
  • Small Molecule Dysregulation of TEAD Lipidation Induces a Dominant-Negative Inhibition of Hippo Pathway Signaling, 2020, Cell Reports
  • Discovery of Pyrido[2,3-b]indole Derivatives with Gram-Negative Activity Targeting Both DNA Gyrase and Topoisomerase IV, 2020, Journal of Medicinal Chemistry
  • A synthetic STING agonist inhibits the replication of human parainfluenza virus 3 and rhinovirus 16 through distinct mechanisms, 2020, Antiviral Research
  • Small molecule approaches to treat autoimmune and inflammatory diseases (Part III): Targeting cytokines and cytokine receptor complexes, 2021, Bioorganic & Medicinal Chemistry Letters

Collaborations form an important part of Shen's work. Frequent co-authors include:

  • Xuefei Tan
  • Wei Zhu
  • Jun Wu
  • Xiao Ding
  • Fabian Dey

Overall, Hong C. Shen's expertise spans foundational and applied aspects within organic chemistry and medicine, with an emphasis on viral infections, immune signaling, and synthetic methods relevant to drug discovery and development.

Best Publications

  • Recent advances in syntheses of heterocycles and carbocycles via homogeneous gold catalysis. Part 1: Heteroatom addition and hydroarylation reactions of alkynes, allenes, and alkenes

    Hong C. Shen

  • Recent advances in syntheses of carbocycles and heterocycles via homogeneous gold catalysis. Part 2: Cyclizations and cycloadditions

    Hong C. Shen

  • Discovery of inhibitors of soluble epoxide hydrolase: a target with multiple potential therapeutic indications.

    Hong C. Shen;Bruce D. Hammock

  • Ruthenium-Catalyzed Intramolecular [5 + 2] Cycloadditions

    Barry M. Trost;and F. Dean Toste;Hong Shen

  • Asymmetric synthesis of chiral chromans

    Hong C. Shen

  • Synthesis of chiral chromans by the Pd-catalyzed asymmetric allylic alkylation (AAA): scope, mechanism, and applications.

    Barry M Trost;Hong C Shen;Li Dong;Jean-Philippe Surivet

  • Palladium-Catalyzed Suzuki−Miyaura Coupling of Pyridyl-2-boronic Esters with Aryl Halides Using Highly Active and Air-Stable Phosphine Chloride and Oxide Ligands

    David X. Yang;Steven L. Colletti;Kevin Wu;Maoying Song

  • Syntheses of Seven-Membered Rings: Ruthenium-Catalyzed Intramolecular [5+2] Cycloadditions

    Barry M. Trost;Hong C. Shen;Daniel B. Horne;F. Dean Toste

  • Small Molecule Dysregulation of TEAD Lipidation Induces a Dominant-Negative Inhibition of Hippo Pathway Signaling.

    Jeffrey K. Holden;James J. Crawford;Cameron L. Noland;Stephen Schmidt

  • Unusual Effects in the Pd-Catalyzed Asymmetric Allylic Alkylations: Synthesis of Chiral Chromans

    Barry M. Trost;Hong C. Shen;Li Dong;Jean-Philippe Surivet

  • Heteroaryldihydropyrimidine (HAP) and Sulfamoylbenzamide (SBA) Inhibit Hepatitis B Virus Replication by Different Molecular Mechanisms.

    Zheng Zhou;Taishan Hu;Xue Zhou;Steffen Wildum

  • 6-bridged heteroaryldihydropyrimidines for the treatment and prophylaxis of hepatitis B virus infection

    Lei Guo;Taishan Hu;Yimin Hu;Buelent Kocer

  • Constructing Tricyclic Compounds Containing a Seven‐Membered Ring by Ruthenium‐Catalyzed Intramolecular [5+2] Cycloaddition

    Barry M. Trost;Hong C. Shen

  • Biomimetic enantioselective total synthesis of (-)-siccanin via the Pd-catalyzed asymmetric allylic alkylation (AAA) and sequential radical cyclizations.

    Barry M. Trost;Hong C. Shen;Jean-Philippe Surivet

  • An Enantioselective Biomimetic Total Synthesis of (−)-Siccanin

    Barry M. Trost;Hong C. Shen;Jean-Philippe Surivet

  • Soluble epoxide hydrolase inhibitors: a patent review.

    Hong C Shen

  • Discovery of Imidazopyridine Derivatives as Highly Potent Respiratory Syncytial Virus Fusion Inhibitors

    Song Feng;Di Hong;Baoxia Wang;Xiufang Zheng

  • Sequential 1,2-Addition−Electrocyclic Ring Closures Involving Acyclic α,β-Unsaturated Iminiums: A Formal [3 + 3] Cycloaddition Strategy to Unique Pyranyl Spirocycles

    Richard P. Hsung;Hong C. Shen;Christopher J. Douglas;Christopher D. Morgan

  • A Formal [3 + 3] Cycloaddition Reaction. Improved Reactivity Using α,β-Unsaturated Iminium Salts and Evidence for Reversibility of 6π-Electron Electrocyclic Ring Closure of 1-Oxatrienes

    Hong C. Shen;Jiashi Wang;Kevin P. Cole;Michael J. McLaughlin

  • On the regioselectivity of the Ru-catalyzed intramolecular [5 + 2] cycloaddition.

    Barry M. Trost;Hong C. Shen

  • Gold(I)-Catalyzed Regioselective Cyclizations of Silyl Ketene Amides and Carbamates with Alkynes

    Ellen C. Minnihan;Steven L. Colletti;F. Dean Toste;Hong C. Shen

Frequent Co-Authors

Barry M. Trost
Barry M. Trost Stanford University
Richard P. Hsung
Richard P. Hsung University of Wisconsin–Madison
Andrei S. Batsanov
Andrei S. Batsanov Durham University
Andrew Whiting
Andrew Whiting Durham University
Xuhong Qian
Xuhong Qian East China University of Science and Technology
F. Dean Toste
F. Dean Toste University of California, Berkeley
Sophie Roy
Sophie Roy MSD (United States)
Jeffrey J. Hale
Jeffrey J. Hale MSD (United States)
Yu-Cheng Gu
Yu-Cheng Gu Syngenta (Switzerland)
Sheo B. Singh
Sheo B. Singh MSD (United States)

External Links

Personal website of Hong C. Shen

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Best Scientists Citing Hong C. Shen

Bruce D. Hammock

Bruce D. Hammock

University of California, Davis

Publications: 83

A. Stephen K. Hashmi

A. Stephen K. Hashmi

Heidelberg University

Publications: 55

Christophe Morisseau

Christophe Morisseau

University of California, Davis

Publications: 44

Richard P. Hsung

Richard P. Hsung

University of Wisconsin–Madison

Publications: 39

Barry M. Trost

Barry M. Trost

Stanford University

Publications: 25

Véronique Michelet

Véronique Michelet

Centre national de la recherche scientifique, CNRS

Publications: 22

F. Dean Toste

F. Dean Toste

University of California, Berkeley

Publications: 21

Frank Rominger

Frank Rominger

Heidelberg University

Publications: 21

Matthias Rudolph

Matthias Rudolph

Heidelberg University

Publications: 16

Ben Shen

Ben Shen

Scripps Research Institute

Publications: 15

Marco Bandini

Marco Bandini

University of Bologna

Publications: 15

Junliang Zhang

Junliang Zhang

Fudan University

Publications: 15

Weiping Tang

Weiping Tang

University of Wisconsin–Madison

Publications: 15

Norbert Krause

Norbert Krause

TU Dortmund University

Publications: 15

Erik V. Van der Eycken

Erik V. Van der Eycken

KU Leuven

Publications: 15

Stefan Offermanns

Stefan Offermanns

Max Planck Society

Publications: 15

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