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Carolyn B. Coyne

Carolyn B. Coyne

D-Index & Metrics

Microbiology

D-Index
65
Citations
24636
World Ranking
2462
National Ranking
996

Overview

Carolyn B. Coyne is affiliated with Duke University in the United States. Their research primarily spans the fields of Medicine and Immunology and Microbiology, with notable emphasis on several subfields including Epidemiology, Immunology, Obstetrics and Gynecology, Infectious Diseases, and Cardiology and Cardiovascular Medicine.

Their research work covers a range of topics, particularly centered on infections and immune responses related to pregnancy and viral pathogens. Key topics addressed by Coyne include:

  • Cytomegalovirus and herpesvirus research
  • Reproductive System and Pregnancy
  • Pregnancy and preeclampsia studies
  • Viral Infections and Immunology Research
  • Viral gastroenteritis research and epidemiology
  • Respiratory viral infections research
  • Interferon and immune responses

Coyne has contributed to numerous scientific papers, some of which have garnered significant citations. Selected publications include:

  • "Infections at the maternal-fetal interface: an overview of pathogenesis and defence", 2021, Nature Reviews Microbiology
  • "Innate immune signaling in trophoblast and decidua organoids defines differential antiviral defenses at the maternal-fetal interface", 2022, eLife
  • "Evolution and antiviral activity of a human protein of retroviral origin", 2022, Science
  • "A standardized definition of placental infection by SARS-CoV-2, a consensus statement from the National Institutes of Health/Eunice Kennedy Shriver National Institute of Child Health and Human Development SARS-CoV-2 Placental Infection Workshop", 2021, American Journal of Obstetrics and Gynecology
  • "Dengue Virus Targets Nrf2 for NS2B3-Mediated Degradation Leading to Enhanced Oxidative Stress and Viral Replication", 2020, Journal of Virology

Frequent collaborators in their work include Liheng Yang, Alexandra I. Wells, Christina Megli, Eleanor C. Semmes, and Anne Caldwell.

Coyne's research has been published across multiple venues, with a strong presence in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • eLife
  • Journal of Virology
  • Journal of Cell Science
  • The Journal of Experimental Medicine

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • PAMPs and DAMPs: Signal 0s that Spur Autophagy and Immunity

    Daolin Tang;Rui Kang;Carolyn B. Coyne;Herbert J. Zeh

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Virus-induced Abl and Fyn kinase signals permit coxsackievirus entry through epithelial tight junctions

    Carolyn B. Coyne;Carolyn B. Coyne;Jeffrey M. Bergelson;Jeffrey M. Bergelson

  • Immune responses at the maternal-fetal interface.

    Stephanie E. Ander;Michael S. Diamond;Carolyn B. Coyne

  • Type III Interferons Produced by Human Placental Trophoblasts Confer Protection against Zika Virus Infection

    Avraham Bayer;Nicholas J. Lennemann;Yingshi Ouyang;John C. Bramley

  • Human placental trophoblasts confer viral resistance to recipient cells

    Elizabeth Delorme-Axford;Rogier B. Donker;Jean-Francois Mouillet;Tianjiao Chu

  • Tight junction proteins claudin-1 and occludin control hepatitis C virus entry and are downregulated during infection to prevent superinfection.

    Shufeng Liu;Wei Yang;Le Shen;Jerrold R. Turner

  • Microbial Vertical Transmission During Human Pregnancy

    Nitin Arora;Yoel Sadovsky;Terence S. Dermody;Carolyn B. Coyne;Carolyn B. Coyne

  • Infections at the maternal-fetal interface: an overview of pathogenesis and defence.

    Christina J. Megli;Carolyn B. Coyne

  • Zika virus - reigniting the TORCH.

    Carolyn B. Coyne;Helen M. Lazear

  • Regulation of Airway Tight Junctions by Proinflammatory Cytokines

    Carolyn B. Coyne;Miriam K. Vanhook;Todd M. Gambling;Johnny L. Carson

  • Role of claudin interactions in airway tight junctional permeability.

    Carolyn B. Coyne;Todd M. Gambling;Richard C. Boucher;Johnny L. Carson

  • The Coxsackievirus B 3Cpro Protease Cleaves MAVS and TRIF to Attenuate Host Type I Interferon and Apoptotic Signaling

    Amitava Mukherjee;Stefanie A. Morosky;Elizabeth Delorme-Axford;Naomi Dybdahl-Sissoko

  • CAR: A virus receptor within the tight junction

    Carolyn B Coyne;Jeffrey M Bergelson

  • Coxsackievirus entry across epithelial tight junctions requires occludin and the small GTPases Rab34 and Rab5.

    Carolyn B. Coyne;Le Shen;Jerrold R. Turner;Jeffrey M. Bergelson;Jeffrey M. Bergelson

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Antiviral Activity of Human OASL Protein Is Mediated by Enhancing Signaling of the RIG-I RNA Sensor

    Jianzhong Zhu;Yugen Zhang;Arundhati Ghosh;Rolando A. Cuevas

  • Type I interferons instigate fetal demise after Zika virus infection

    Laura J. Yockey;Kellie A. Jurado;Nitin Arora;Alon Millet

  • Review: placenta-specific microRNAs in exosomes - good things come in nano-packages.

    Yingshi Ouyang;Jean-Francois Mouillet;Carolyn B. Coyne;Yoel Sadovsky

  • Dengue and Zika viruses subvert reticulophagy by NS2B3-mediated cleavage of FAM134B.

    Nicholas J. Lennemann;Carolyn B. Coyne

  • Mechanisms of MAVS regulation at the mitochondrial membrane.

    Jana L. Jacobs;Carolyn B. Coyne

Frequent Co-Authors

Yoel Sadovsky
Yoel Sadovsky University of Pittsburgh
Sara Cherry
Sara Cherry University of Pennsylvania
Evelina Gatti
Evelina Gatti Aix-Marseille University
Michael S. Diamond
Michael S. Diamond Washington University in St. Louis
Kwang Sik Kim
Kwang Sik Kim Johns Hopkins University School of Medicine
Shazib Pervaiz
Shazib Pervaiz National University of Singapore
Jeffrey M. Bergelson
Jeffrey M. Bergelson Children's Hospital of Philadelphia
Yee-Joo Tan
Yee-Joo Tan National University of Singapore
Veit Hornung
Veit Hornung Ludwig-Maximilians-Universität München
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center

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