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Biology and Biochemistry

D-Index
75
Citations
42463
World Ranking
5182
National Ranking
18

Overview

Shazib Pervaiz is affiliated with the National University of Singapore in Singapore. Their research activity spans multiple core areas within biochemistry, genetics, molecular biology, and medicine, focusing extensively on molecular biology and oncology.

Their work has been published across a variety of scientific journals and venues, including:

  • Cancer Research
  • Redox Biology
  • Theranostics
  • RSC Advances
  • Cell Death and Disease

Key topics addressed in their research include:

  • Mitochondrial Function and Pathology
  • Cell death mechanisms and regulation
  • Autophagy in Disease and Therapy
  • Cancer therapeutics and mechanisms
  • Telomeres, Telomerase, and Senescence
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Cancer, Hypoxia, and Metabolism

The scientist collaborates frequently with several coauthors, notably:

  • Jayshree L. Hirpara
  • Stephen Jun Fei Chong
  • Deepika Raman
  • Kartini Iskandar
  • Jolin Xiao Hui Lai

Several recent papers by Shazib Pervaiz illustrate their research focus and contributions:

  • "Mitochondria-mediated oxidative stress during viral infection," 2022, published in Trends in Microbiology
  • "Noncanonical Cell Fate Regulation by Bcl-2 Proteins," 2020, published in Trends in Cell Biology
  • "Targeting Mitochondrial Apoptosis to Overcome Treatment Resistance in Cancer," 2020, published in Cancers
  • "The redox-senescence axis and its therapeutic targeting," 2021, published in Redox Biology
  • "Serine-70 phosphorylated Bcl-2 prevents oxidative stress-induced DNA damage by modulating the mitochondrial redox metabolism," 2020, published in Nucleic Acids Research

The concentration of publications in cancer research, redox biology, and molecular mechanisms related to cell death and mitochondrial function aligns with their focus on understanding disease mechanisms and therapeutic approaches across cancer and cellular pathology.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

    Lorenzo Galluzzi;Ilio Vitale;Stuart A. Aaronson;John M. Abrams

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Chemopreventive Agent Resveratrol, a Natural Product Derived From Grapes, Triggers CD95 Signaling-Dependent Apoptosis in Human Tumor Cells

    Marie-Véronique Clément;Jayshreekumari L. Hirpara;Sanaul-Haq Chawdhury;Shazib Pervaiz

  • Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes

    L. Galluzzi;L. Galluzzi;L. Galluzzi;S. A. Aaronson;J. Abrams;E. S. Alnemri

  • Resveratrol: from grapevines to mammalian biology

    Shazib Pervaiz

  • Recent advances in apoptosis, mitochondria and drug resistance in cancer cells.

    Inthrani R. Indran;Grégory Tufo;Grégory Tufo;Shazib Pervaiz;Catherine Brenner;Catherine Brenner

  • Annexin 1: the new face of an old molecule

    Lina H. K. Lim;Shazib Pervaiz

  • Resveratrol: its biologic targets and functional activity.

    Shazib Pervaiz;Andrea Lisa Holme

  • Reactive oxygen species and the mitochondrial signaling pathway of cell death

    M. Le Bras;M.V. Clément;S. Pervaiz;C. Brenner

  • TNF receptor superfamily-induced cell death: redox-dependent execution

    Han-Ming Shen;Shazib Pervaiz

  • Cancer stem cell: target for anti-cancer therapy

    Carol Tang;Beng T. Ang;Shazib Pervaiz

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • hTERT overexpression alleviates intracellular ROS production, improves mitochondrial function, and inhibits ROS-mediated apoptosis in cancer cells

    Inthrani R. Indran;Manoor P. Hande;Shazib Pervaiz

  • Do STAT3 inhibitors have potential in the future for cancer therapy

    Andrea L.A. Wong;Jayshree L. Hirpara;Shazib Pervaiz;Jie-Qing Eu

  • Apoptosis induced by hydrogen peroxide is mediated by decreased superoxide anion concentration and reduction of intracellular milieu

    Marie-Véronique Clément;Andre Ponton;Shazib Pervaiz

  • Simultaneous Induction of Non-Canonical Autophagy and Apoptosis in Cancer Cells by ROS-Dependent ERK and JNK Activation

    Chew Hooi Wong;Kartini Bte Iskandar;Sanjiv Kumar Yadav;Jayshree L. Hirpara

  • Redox Regulation of p53, Redox Effectors Regulated by p53: A Subtle Balance

    Agnès Maillet;Shazib Pervaiz

  • Redox regulation of cancer cell migration and invasion.

    Lalchhandami Tochhawng;Shuo Deng;Shazib Pervaiz;Celestial T. Yap

Frequent Co-Authors

Catherine Brenner
Catherine Brenner Université Paris Cité
Alan Prem Kumar
Alan Prem Kumar National University of Singapore
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center
Gerry Melino
Gerry Melino University of Rome Tor Vergata
Boris Zhivotovsky
Boris Zhivotovsky Karolinska Institute
Guido Kroemer
Guido Kroemer Université Paris Cité
Lorenzo Galluzzi
Lorenzo Galluzzi Cornell University
Simone Fulda
Simone Fulda Goethe University Frankfurt
Evelina Gatti
Evelina Gatti Aix-Marseille University
Oliver Kepp
Oliver Kepp Institut Gustave Roussy

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