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Biology and Biochemistry

D-Index
59
Citations
16313
World Ranking
12353
National Ranking
247

Overview

Laura Senovilla is affiliated with the University of Valladolid in Spain. Their research interests primarily span the fields of Biochemistry, Genetics and Molecular Biology, with a considerable focus on Medicine. They have contributed extensively to subfields such as Molecular Biology, Cancer Research, Oncology, Cell Biology, and Pulmonary and Respiratory Medicine.

Their work frequently addresses topics including Cancer Immunotherapy and Biomarkers, Endoplasmic Reticulum Stress and Disease, Cancer Genomics and Diagnostics, Cancer, Lipids, and Metabolism, DNA Repair Mechanisms, Ferroptosis and Cancer Prognosis, and the relationship between Cancer, Stress, Anesthesia, and Immune Response.

Laura Senovilla has published multiple papers in several scientific journals, with recurring appearances in the International Journal of Molecular Sciences, Methods in Molecular Biology, Nature Communications, Cell Death and Disease, and Frontiers in Oncology.

  • Immunoprophylactic and immunotherapeutic control of hormone receptor-positive breast cancer, 2020, Nature Communications
  • ACBP/DBI protein neutralization confers autophagy-dependent organ protection through inhibition of cell loss, inflammation, and fibrosis, 2022, Proceedings of the National Academy of Sciences
  • Involvement of Bcl-2 Family Proteins in Tetraploidization-Related Senescence, 2023, International Journal of Molecular Sciences
  • Obesity-Associated Colorectal Cancer, 2024, International Journal of Molecular Sciences
  • Everolimus and plicamycin specifically target chemoresistant colorectal cancer cells of the CMS4 subtype, 2021, Cell Death and Disease

Collaborations have been a notable aspect of Senovilla's research activity. Frequent co-authors include Guido Kroemer, Juliette Humeau, Omar Motiño, Daniel Barriuso, and Lucia Alvarez-Frutos. These collaborations reflect a network within cancer biology and molecular medicine research communities.

Laura Senovilla's research outputs reflect an integration of molecular biology techniques and approaches to study complex mechanisms underlying cancer biology, cellular stress responses, and therapeutic interventions. Their publications highlight investigations into immunotherapy, autophagy, cellular senescence, metabolic influences on cancer, and mechanisms of drug resistance.

Best Publications

  • Molecular mechanisms of cisplatin resistance

    L Galluzzi;L Senovilla;L Senovilla;L Senovilla;I Vitale;I Vitale;I Vitale;J Michels;J Michels;J Michels

  • Consensus guidelines for the detection of immunogenic cell death

    Oliver Kepp;Laura Senovilla;Ilio Vitale;Erika Vacchelli

  • The secret ally: immunostimulation by anticancer drugs

    Lorenzo Galluzzi;Laura Senovilla;Laura Senovilla;Laurence Zitvogel;Guido Kroemer

  • Classification of current anticancer immunotherapies

    Lorenzo Galluzzi;Erika Vacchelli;José Manuel Bravo-San Pedro;Aitziber Buqué

  • Caloric Restriction Mimetics Enhance Anticancer Immunosurveillance

    Federico Pietrocola;Federico Pietrocola;Jonathan Pol;Erika Vacchelli;Erika Vacchelli;Shuan Rao

  • Regulation of Autophagy by Cytosolic Acetyl-Coenzyme A

    Guillermo Mariño;Federico Pietrocola;Tobias Eisenberg;Yongli Kong

  • An immunosurveillance mechanism controls cancer cell ploidy

    Laura Senovilla;Laura Senovilla;Laura Senovilla;Ilio Vitale;Ilio Vitale;Ilio Vitale;Isabelle Martins;Isabelle Martins;Isabelle Martins;Maximilien Tailler;Maximilien Tailler;Maximilien Tailler

  • Immunogenic Tumor Cell Death for Optimal Anticancer Therapy: The Calreticulin Exposure Pathway

    Laurence Zitvogel;Oliver Kepp;Laura Senovilla;Laurie Menger

  • The IKK complex contributes to the induction of autophagy

    Alfredo Criollo;Laura Senovilla;Laura Senovilla;Laura Senovilla;Hélène Authier;Maria Chiara Maiuri

  • miR-181a and miR-630 Regulate Cisplatin-Induced Cancer Cell Death

    Lorenzo Galluzzi;Eugenia Morselli;Ilio Vitale;Oliver Kepp

  • Trial watch: Prognostic and predictive value of the immune infiltrate in cancer.

    Laura Senovilla;Erika Vacchelli;Jerome Galon;Sandy Adjemian

  • Chemotherapy induces ATP release from tumor cells.

    Isabelle Martins;Antoine Tesniere;Oliver Kepp;Mickael Michaud

  • Crizotinib-induced immunogenic cell death in non-small cell lung cancer

    Peng Liu;Liwei Zhao;Jonathan Pol;Sarah Levesque

  • Natural and therapy-induced immunosurveillance in breast cancer

    Guido Kroemer;Laura Senovilla;Lorenzo Galluzzi;Fabrice André;Fabrice André

  • Cytoplasmic STAT3 represses autophagy by inhibiting PKR activity.

    Shensi Shen;Mireia Niso-Santano;Mireia Niso-Santano;Mireia Niso-Santano;Sandy Adjemian;Sandy Adjemian;Sandy Adjemian;Tetsuo Takehara

  • Hierarchical involvement of Bak, VDAC1 and Bax in cisplatin-induced cell death.

    N Tajeddine;L. Galluzzi;L. Galluzzi;L. Galluzzi;O Kepp;O Kepp;O Kepp;E Hangen;E Hangen;E Hangen

  • Trial watch: Chemotherapy with immunogenic cell death inducers.

    Erika Vacchelli;Laura Senovilla;Alexander Eggermont;Wolf Hervé Fridman

  • Immunogenic cell death modalities and their impact on cancer treatment.

    Oliver Kepp;Antoine Tesniere;Antoine Tesniere;Antoine Tesniere;Frederic Schlemmer;Frederic Schlemmer;Frederic Schlemmer;Mickael Michaud;Mickael Michaud;Mickael Michaud

  • Crosstalk between ER stress and immunogenic cell death.

    Oliver Kepp;Laurie Menger;Laurie Menger;Laurie Menger;Erika Vacchelli;Erika Vacchelli;Erika Vacchelli;Clara Locher;Clara Locher

  • Trial watch: Dendritic cell-based interventions for cancer therapy.

    Erika Vacchelli;Ilio Vitale;Alexander Eggermont;Wolf Hervé Fridman

Frequent Co-Authors

Guido Kroemer
Guido Kroemer Université Paris Cité
Oliver Kepp
Oliver Kepp Institut Gustave Roussy
Lorenzo Galluzzi
Lorenzo Galluzzi Cornell University
Maria Castedo
Maria Castedo Université Paris Cité
Ilio Vitale
Ilio Vitale University of Rome Tor Vergata
Isabelle Martins
Isabelle Martins Inserm : Institut national de la santé et de la recherche médicale
Erika Vacchelli
Erika Vacchelli Université Paris Cité
Laurence Zitvogel
Laurence Zitvogel University of Paris-Saclay
Guillermo Mariño
Guillermo Mariño University of Oviedo
Alfredo Criollo
Alfredo Criollo University of Chile

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