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Neuroscience

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Overview

Jari Tiihonen is affiliated with the Karolinska Institute in Sweden and has a substantial body of research in the field of medicine, with a focus on psychiatry and mental health. Their work encompasses clinical psychology, pharmacology, social psychology, and genetics, contributing to a broad understanding of mental health disorders and treatment strategies.

The scientist's research prominently addresses schizophrenia, with a significant emphasis on schizophrenia research and treatment. Other notable topics include bipolar disorder and treatment, electroconvulsive therapy studies, treatment of major depression, mental health treatment and access, mental health and psychiatry, and tryptophan and brain disorders.

Jari Tiihonen's recent publications illustrate their sustained engagement in schizophrenia and psychiatric research. Key papers include:

  • Mortality in people with schizophrenia: a systematic review and meta-analysis of relative risk and aggravating or attenuating factors, 2022, World Psychiatry
  • 20-year follow-up study of physical morbidity and mortality in relationship to antipsychotic treatment in a nationwide cohort of 62,250 patients with schizophrenia (FIN20), 2020, World Psychiatry
  • Half a century of research on antipsychotics and schizophrenia: A scientometric study of hotspots, nodes, bursts, and trends, 2022, Neuroscience & Biobehavioral Reviews
  • The clinical course of schizophrenia in women and men-a nation-wide cohort study, 2020, Schizophrenia
  • Antipsychotic use and risk of breast cancer in women with schizophrenia: a nationwide nested case-control study in Finland, 2021, The Lancet Psychiatry

The scientist frequently collaborates with researchers such as Heidi Taipale, Markku Lähteenvuo, Antti Tanskanen, Ellenor Mittendorfer-Rutz, and Christoph U. Correll.

Jari Tiihonen has published extensively in a range of academic journals, including:

  • Schizophrenia Bulletin
  • The Lancet Psychiatry
  • European Neuropsychopharmacology
  • Acta Psychiatrica Scandinavica
  • bioRxiv (Cold Spring Harbor Laboratory)

Best Publications

  • 11-year follow-up of mortality in patients with schizophrenia: a population-based cohort study (FIN11 study).

    Jari Tiihonen;Jari Tiihonen;Jouko Lönnqvist;Kristian Wahlbeck;Timo Klaukka

  • A Nationwide Cohort Study of Oral and Depot Antipsychotics After First Hospitalization for Schizophrenia

    Jari Tiihonen;Jari Haukka;Mark Taylor;Peter M. Haddad

  • Mortality in people with schizophrenia: a systematic review and meta‐analysis of relative risk and aggravating or attenuating factors

    Unknown

  • Real-World Effectiveness of Antipsychotic Treatments in a Nationwide Cohort of 29 823 Patients With Schizophrenia

    Jari Tiihonen;Ellenor Mittendorfer-Rutz;Maila Majak;Juha Mehtälä

  • Specific major mental disorders and criminality: a 26-year prospective study of the 1966 northern Finland birth cohort.

    Jari Tiihonen;Matti Isohanni;Pirkko Räsänen;Markku Koiranen

  • Mental Disorders and Homicidal Behavior in Finland

    Markku Eronen;Panu Hakola;Jari Tiihonen

  • Quantitative MRI of the hippocampus and amygdala in severe depression.

    E. Mervaala;J. Föhr;M. Könönen;M. Valkonen-Korhonen

  • Effectiveness of antipsychotic treatments in a nationwide cohort of patients in community care after first hospitalisation due to schizophrenia and schizoaffective disorder: observational follow-up study.

    Jari Tiihonen;Kristian Wahlbeck;Jouko Lönnqvist;Timo Klaukka

  • 20-year follow-up study of physical morbidity and mortality in relationship to antipsychotic treatment in a nationwide cohort of 62,250 patients with schizophrenia (FIN20).

    Heidi Taipale;Heidi Taipale;Antti Tanskanen;Antti Tanskanen;Antti Tanskanen;Juha Mehtälä;Pia Vattulainen

  • Dopamine reuptake site densities in patients with social phobia.

    Jari Tiihonen;Jyrki Kuikka;Kim Bergström;Ulla Lepola

  • Schizophrenia and Homicidal Behavior

    Markku Eronen;Jari Tiihonen;Panu Hakola

  • Antidepressants and the risk of suicide, attempted suicide, and overall mortality in a nationwide cohort.

    Jari Tiihonen;Jouko Lönnqvist;Kristian Wahlbeck;Timo Klaukka

  • Psychopathy and the posterior hippocampus.

    Mikko P. Laakso;Olli Vaurio;Esa Koivisto;Liisa Savolainen

  • Association between low activity serotonin transporter promoter genotype and early onset alcoholism with habitual impulsive violent behavior.

    T. Hallikainen;T. Saito;H. M. Lachman;Jan Volavka

  • Schizophrenia, Alcohol Abuse, and Violent Behavior: A 26-Year Followup Study of an Unselected Birth Cohort

    Pirkko Räsänen;Jari Tiihonen;Matti Isohanni;Paula Rantakallio

  • Polypharmacy with antipsychotics, antidepressants, or benzodiazepines and mortality in schizophrenia.

    Jari Tiihonen;Jaana T. Suokas;Jaana M. Suvisaari;Jari Haukka

  • Antipsychotic Treatment and Mortality in Schizophrenia

    Minna Torniainen;Ellenor Mittendorfer-Rutz;Antti Tanskanen;Charlotte Björkenstam

  • Association of Antipsychotic Polypharmacy vs Monotherapy With Psychiatric Rehospitalization Among Adults With Schizophrenia

    Jari Tiihonen;Jari Tiihonen;Heidi Taipale;Heidi Taipale;Juha Mehtälä;Pia Vattulainen

  • Long-term use of benzodiazepines: Definitions, prevalence and usage patterns – a systematic review of register-based studies

    T.A.T. Kurko;T.A.T. Kurko;L.K. Saastamoinen;S. Tähkäpää;A. Tuulio-Henriksson

  • Antipsychotics and mortality in a nationwide cohort of 29,823 patients with schizophrenia

    Heidi Taipale;Ellenor Mittendorfer-Rutz;Kristina Alexanderson;Maila Majak

  • Maternal smoking during pregnancy and risk of criminal behavior among adult male offspring in the Northern Finland 1966 Birth Cohort.

    Pirkko Räsänen;Helinä Hakko;Matti Isohanni;Sheilagh Hodgins

  • Altered striatal dopamine re-uptake site densities in habitually violent and non-violent alcoholics.

    Jari Tiihonen;Jyrki Kuikka;Jyrki Kuikka;Kim Bergström;Kim Bergström;Panu Hakola;Panu Hakola

  • Association Between the Functional Variant of the catechol-O-methyltransferase (COMT) Gene and Type 1 Alcoholism

    Tiihonen J;Hallikainen T;Lachman H;Saito T

  • Amygdala-orbitofrontal structural and functional connectivity in females with anxiety disorders, with and without a history of conduct disorder.

    Philip Lindner;Pär Flodin;Peter Larm;Meenal Budhiraja

Frequent Co-Authors

Jari Haukka
Jari Haukka University of Helsinki
Tiina Paunio
Tiina Paunio University of Helsinki
Sheilagh Hodgins
Sheilagh Hodgins University of Montreal
Jouko Lönnqvist
Jouko Lönnqvist Finnish Institute for Health and Welfare (THL)
Matti Virkkunen
Matti Virkkunen University of Helsinki
Jarmo Hietala
Jarmo Hietala Turku University Hospital
Jari Karhu
Jari Karhu Nexstim (Finland)
Johannes Lehtonen
Johannes Lehtonen University of Eastern Finland
Jaana Suvisaari
Jaana Suvisaari Finnish Institute for Health and Welfare (THL)
Heimo Viinamäki
Heimo Viinamäki University of Eastern Finland

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