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Biology and Biochemistry

D-Index
46
Citations
10136
World Ranking
18870
National Ranking
7710

Overview

Dimitri S. Monos is affiliated with the Children's Hospital of Philadelphia in the United States. Their research spans several areas within medicine and immunology, focusing on the cellular and molecular underpinnings of immune response and transplantation outcomes.

Their primary fields of study include Medicine and Immunology and Microbiology, with a significant focus on the subfields of Immunology, Hematology, Molecular Biology, Transplantation, and Genetics.

Core topics of their research cover:

  • T-cell and B-cell Immunology
  • Immune Cell Function and Interaction
  • Renal Transplantation Outcomes and Treatments
  • Hematopoietic Stem Cell Transplantation
  • Dermatology and Skin Diseases
  • Immunodeficiency and Autoimmune Disorders
  • CAR-T cell therapy research

Monos has contributed to multiple peer-reviewed journals, with frequent publications appearing in venues such as:

  • Human Immunology
  • Transplantation and Cellular Therapy
  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Journal of Immunology
  • Blood

Recent papers authored or co-authored by Monos include:

  • Next-generation sequencing technologies: An overview, 2021, Human Immunology
  • Lifetime and Stability of Silicon Nitride Nanopores and Nanopore Arrays for Ionic Measurements, 2020, ACS Nano
  • Severe delayed hypersensitivity reactions to IL-1 and IL-6 inhibitors link to common HLA-DRB1*15 alleles, 2021, Annals of the Rheumatic Diseases
  • Utilizing nanopore sequencing technology for the rapid and comprehensive characterization of eleven HLA loci; addressing the need for deceased donor expedited HLA typing, 2020, Human Immunology
  • Accurate long-read sequencing allows assembly of the duplicated RHD and RHCE genes harboring variants relevant to blood transfusion, 2021, The American Journal of Human Genetics

Collaborative work is a notable aspect of Monos's career, with frequent co-authors including:

  • Jamie L. Duke
  • Timothy L. Mosbruger
  • Deborah Ferriola
  • Tristan J. Hayeck
  • Nancy Bunin

The scope of Monos's research reflects integration of advanced sequencing technologies and immunogenetics to address clinical challenges such as transplantation and immune hypersensitivity reactions. Their work on long-read sequencing approaches and HLA locus characterization contributes to the broader understanding of immune compatibility and blood transfusion genetics.

Best Publications

  • A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene

    Hakon Hakonarson;Struan F A Grant;Jonathan P. Bradfield;Luc Marchand

  • Common variants at five new loci associated with early-onset inflammatory bowel disease.

    Marcin Imielinski;Robert N. Baldassano;Anne Griffiths;Richard K. Russell

  • Next-generation sequencing technologies: An overview.

    Taishan Hu;Nilesh Chitnis;Dimitri Monos;Dimitri Monos;Anh Dinh;Anh Dinh

  • Personalized cancer vaccine effectively mobilizes antitumor T cell immunity in ovarian cancer

    Janos L. Tanyi;Sara Bobisse;Eran Ophir;Sandra Tuyaerts

  • Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease

    Subra Kugathasan;Robert N Baldassano;Jonathan P Bradfield;Patrick M A Sleiman

  • HLA-DRB1*1101: A Significant Risk Factor for Sarcoidosis in Blacks and Whites

    Milton D. Rossman;Bruce Thompson;Margaret Frederick;Mary Maliarik

  • A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci.

    Jonathan P. Bradfield;Hui Qi Qu;Kai Wang;Haitao Zhang

  • Structural basis for major histocompatibility complex (MHC)-linked susceptibility to autoimmunity: charged residues of a single MHC binding pocket confer selective presentation of self-peptides in pemphigus vulgaris.

    K W Wucherpfennig;B Yu;K Bhol;D S Monos

  • Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases

    Yun R Li;Jin Li;Sihai D Zhao;Sihai D Zhao;Jonathan P Bradfield

  • From disease association to risk assessment: an optimistic view from genome-wide association studies on type 1 diabetes.

    Zhi Wei;Kai Wang;Hui Qi Qu;Haitao Zhang

  • Human TCR-gamma+/delta+, CD8+ T lymphocytes recognize tetanus toxoid in an MHC-restricted fashion.

    D Kozbor;G Trinchieri;D S Monos;M Isobe

  • Comparative genetic analysis of inflammatory bowel disease and type 1 diabetes implicates multiple loci with opposite effects.

    Kai Wang;Robert Baldassano;Haitao Zhang;Hui Qi Qu

  • Next-generation sequencing: the solution for high-resolution, unambiguous human leukocyte antigen typing

    C. Lind;D. Ferriola;K. Mackiewicz;S. Heron

  • Follow up analysis of genome-wide association data identifies novel loci for type 1 diabetes

    Struan F.A. Grant;Hui-Qi Qu;Jonathan P. Bradfield;Luc Marchand

  • Human leukocyte antigen Class II amino acid epitopes: susceptibility and progression markers for beryllium hypersensitivity.

    Milton D. Rossman;Jose Stubbs;Chung Wha Lee;Elias Argyris

  • A novel susceptibility locus for type 1 diabetes on Chr12q13 identified by a genome-wide association study

    Hakon Hakonarson;Hui Qi Qu;Jonathan P. Bradfield;Luc Marchand

  • Sensitive and frequent identification of high avidity neo-epitope specific CD8 + T cells in immunotherapy-naive ovarian cancer.

    Sara Bobisse;Raphael Genolet;Annalisa Roberti;Janos L. Tanyi

  • Microtubule actin crosslinking factor 1 regulates the Balbiani body and animal-vegetal polarity of the zebrafish oocyte.

    Tripti Gupta;Florence L. Marlow;Deborah Ferriola;Deborah Ferriola;Katarzyna Mackiewicz;Katarzyna Mackiewicz

  • A multi-site study using high-resolution HLA genotyping by next generation sequencing.

    C. L. Holcomb;B. Höglund;M. W. Anderson;L. A. Blake

  • Insulin dependent diabetes mellitus as an autoimmune disease.

    Monos Ds;Zmijewski Cm

Frequent Co-Authors

Malek Kamoun
Malek Kamoun University of Pennsylvania
Hakon Hakonarson
Hakon Hakonarson Children's Hospital of Philadelphia
Jonathan P. Bradfield
Jonathan P. Bradfield Children's Hospital of Philadelphia
Struan F.A. Grant
Struan F.A. Grant University of Pennsylvania
Joseph T. Glessner
Joseph T. Glessner Children's Hospital of Philadelphia
Rosetta M. Chiavacci
Rosetta M. Chiavacci Children's Hospital of Philadelphia
Constantin Polychronakos
Constantin Polychronakos McGill University Health Centre
Robert N. Baldassano
Robert N. Baldassano Children's Hospital of Philadelphia
Stephan A. Grupp
Stephan A. Grupp Children's Hospital of Philadelphia
David M. Barrett
David M. Barrett Children's Hospital of Philadelphia

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